CITRININ
- CAS No.
- 518-75-2
- Chemical Name:
- CITRININ
- Synonyms
- CIT;ANTIMYCIN;CTRO;NSC 186;CITRININ;KIAA0949;Cltrinin;Citriain;CITRININE;Cytrinine
- CBNumber:
- CB3190931
- Molecular Formula:
- C13H14O5
- Molecular Weight:
- 250.25
- MOL File:
- 518-75-2.mol
- Modify Date:
- 2024/3/25 15:20:08
| Melting point | 175°C (dec.) |
|---|---|
| alpha | D18 -37.4° (c = 1.15 in alc.) |
| Boiling point | 313.38°C (rough estimate) |
| Density | 1.37 |
| refractive index | 1.4560 (estimate) |
| Flash point | 2℃ |
| storage temp. | 2-8°C |
| solubility | ≤2mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide |
| pka | 1.52±0.60(Predicted) |
| form | Crystalline Powder or Flakes |
| color | Yellow |
| Merck | 13,2351 |
| BRN | 5282243 |
| Stability | Hygroscopic |
| CAS DataBase Reference | 518-75-2(CAS DataBase Reference) |
| IARC | 3 (Vol. 40, Sup 7) 1987 |
| EPA Substance Registry System | Citrinin (518-75-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H351 | |||||||||
| Precautionary statements | P202-P261-P280-P301+P310-P302+P352+P312-P304+P340+P311 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 23/24/25-40-36/37/38 | |||||||||
| Safety Statements | 26-36/37/39-45-22-7/9 | |||||||||
| RIDADR | UN 3462 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DJ2275000 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29419090 | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 35, 67 i.p. (Ambrose, De Eds) | |||||||||
| NFPA 704 |
|
CITRININ price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C1017 | Citrinin from Penicillium citrinum, ≥98% (HPLC) | 518-75-2 | 5MG | ₹19365.93 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SAB4500213 | Anti-CTRO antibody produced in rabbit affinity isolated antibody | 518-75-2 | 100μG | ₹50560.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C1017 | Citrinin from Penicillium citrinum, ≥98% (HPLC) | 518-75-2 | 25MG | ₹75526.03 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 35410 | Citrinin solution ~100?μg/mL in acetonitrile, analytical standard | 518-75-2 | 1ML | ₹58799.3 | 2022-06-14 | Buy |
CITRININ Chemical Properties,Uses,Production
Chemical Properties
yellow crystalline powder or flakes
Uses
Citrinin is a quinonemethine mycotoxin produced by diverse fungi including Aspergillus and Penicillium. Citrinin has been extensively investigate, and is a potent nephrotoxin with hepatoxic and teratogenic activity. Citrinin is the causative agent of Balkan nephropathy and yellow rice fever in humans. At the molecular level, citrinin exhibits a range of effects including free radical damage to DNA and disruption of mitochondrial membrane-bound enzymic activities and structural integrity. Specifically, citrinin is an inhibitor of NADH dehydrogenase in the mitochondrial electron transport chain and this action is responsible for recent reports of citrinin's apoptotic activity.
General Description
Citrinin is a hepato-nephrotoxic mycotoxin. It can be produced by several filamentous fungi genera of Monauscus, Aspergillus, and Penicillium, which is commonly found as a contaminant in stored grains, foods, feedstuffs and also in biological fluids.
Potential Exposure
Specific uses for antimycin A were not found, however, antimycin A1, and antimycin A3 are reported to be antibiotic substances produced by streptomyces for use as a fungicide, possible insecticide and miticide. Registered as a pesticide in the U.S.
Shipping
UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
CITRININ Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Madhu Chemicals | 08048970542 | Mumbai, India | 150 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12447 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5873 | 58 | Inquiry |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | China | 973 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21667 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
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