EPOXOMICIN

CAS No.: 134381-21-8

Chemical Name:: EPOXOMICIN

Synonyms: CS-1626;BU-4061T;EPOXOMICIN;Aids010837;Aids-010837;Epoxomicin, 99.5%;BU-4061T,Aids010837;Epoxomicin(BU-4061T);EPOXOMICIN, SYNTHETIC;EPOXOMICIN;BU4061T;BU-4061T

CBNumber:: CB3198331

Molecular Formula:: C28H50N4O7

Molecular Weight:: 554.72

MOL File:: 134381-21-8.mol

MSDS File:: SDS

Modify Date:: 2023/7/12 17:25:21

Request For Quotation

EPOXOMICIN Properties

Melting point	107-109°
alpha	D24.5 -66.1 ± 0.4° (c = 0.5 in MeOH)
Boiling point	795.7±60.0 °C(Predicted)
Density	1.117±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO (up to 10 mg/ml).
pka	13.02±0.46(Predicted)
form	solid
color	White
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChIKey	DOGIDQKFVLKMLQ-JTHVHQAWSA-N

SAFETY

Risk and Safety Statements

WGK Germany	3
HS Code	29299090

EPOXOMICIN price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	E3652	Epoxomicin ≥95% (HPLC), solid	134381-21-8	50μG	₹31533.23	2022-06-14	Buy

Product number	Packaging	Price	Buy
E3652	50μG	₹31533.23	Buy

EPOXOMICIN Chemical Properties,Uses,Production

Uses

Epoxomicin has been used:

as an ubiquitin–proteosome system (UPS) inhibitor in pheochromocytoma PC12 cells
as a proteasome inhibitor in mammary epithelial MCF-10A cells
as a proteasome inhibitor in chymotryptic assay in cardiomyocytes

Definition

ChEBI: A tripeptide consisting of an Ile-Ile-Thr-NH2 sequence N-substituted on the threonamide amidic nitrogen with a (2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl group and with acetyl and meth l groups on the nitrogen of the isoleucine residue distal to the threonamide; a naturally occurring selective proteasome inhibitor with anti-inflammatory activity.

General Description

Epoxomicin is a linear peptide consisting of a threonine or serine residue with α′, β′-epoxyketone?derived from leucine or a γ,δ-dehydroleucine. It is a natural product isolated from?Actinomyces?sp., and is a cell-permeable, potent, selective and irreversible proteasome inhibitor.

EPOXOMICIN Preparation Products And Raw materials

Raw materials

Preparation Products

EPOXOMICIN Suppliers

Global( 105)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Alpha Biopharmaceuticals Co., Ltd	+86-15542445688	China	888	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	China	9240	55	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32835	60	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49403	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29820	58	Inquiry
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	China	9316	58	Inquiry
BOC Sciences	16314854226; +16314854226	United States	19743	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry

Supplier	Advantage
Alpha Biopharmaceuticals Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Hangzhou FandaChem Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
Baoji Guokang Bio-Technology Co., Ltd.	58
BOC Sciences	58
Nextpeptide Inc	58
InvivoChem	58

EPOXOMICIN Spectrum

EPOXOMICIN(134381-21-8)MS

134381-21-8(EPOXOMICIN)Related Search:

1,6-BIS(CYCLOHEXYLOXIMINOCARBONYLAMINO)HEXANE PF-622 Zafirlukast Ginkgolide B EPOXOMICIN MICROBIAL

EPOXOMICIN

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BU-4061T EPOXOMICIN, SYNTHETIC EPOXOMICIN (2R)-2-[ACETYL-(N-METHYL-L-ISOLEUCYL)-L-ISOLEUCYL-L-THREONYL-L-LEUCYL]-2-METHYLOXIRANE n-acetyl-n-methyl-l-isoleucyl-l-isoleucyl-n-[(1s)-3-methyl-1-[[(2r)-2-methyloxiranyl]carbonyl]butyl]-l-threoninamide Aids010837 Aids-010837 L-Threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]- (2S,3S)-2-[[(2S,3S)-2-[acetyl(Methyl)aMino]-3-Methylpentanoyl]aMino]-N-[(2S,3R)-3-hydroxy-2-[[(2S)-4-Methyl-1-[(2R)-2-Methyloxiran-2-yl]-1-oxopentan-2-yl]aMino]butanoyl]-3-MethylpentanaMide N-Acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-threoninamide Epoxomicin, 99.5% CS-1626 Epoxomicin(BU-4061T) EPOXOMICIN;BU4061T;BU-4061T Epoxomicin, 97%, a selective proteasome inhibitor BU-4061T,Aids010837 L-Threoninamide, N-acetyl-N-methyl-L-isoleucyl-L-isoleucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]- 134381-21-8 supplier in China 134381-21-8 C28H50N4O7 Enzymes, Inhibitors, and Substrates Proteasomes Proteasome, Calpain and Lysosomal Proteases Inhibitors BioChemical Biochemicals and Reagents Application Index Cell Signaling Enzymes peptides ProteasomeInhibitors