에폭시마이신
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에폭시마이신 속성
- 녹는점
- 107-109°
- 알파
- D24.5 -66.1 ± 0.4° (c = 0.5 in MeOH)
- 끓는 점
- 795.7±60.0 °C(Predicted)
- 밀도
- 1.117±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- DMSO에 용해됩니다(최대 10mg/ml).
- 산도 계수 (pKa)
- 13.02±0.46(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 하얀색
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO의 솔루션은 -20°에서 최대 2개월 동안 보관할 수 있습니다.
- InChIKey
- DOGIDQKFVLKMLQ-JTHVHQAWSA-N
안전
| WGK 독일 | 3 | ||
|---|---|---|---|
| HS 번호 | 29299090 |
에폭시마이신 C화학적 특성, 용도, 생산
용도
Epoxomicin has been used:- as an ubiquitin–proteosome system (UPS) inhibitor in pheochromocytoma PC12 cells
- as a proteasome inhibitor in mammary epithelial MCF-10A cells
- as a proteasome inhibitor in chymotryptic assay in cardiomyocytes
정의
ChEBI: A tripeptide consisting of an Ile-Ile-Thr-NH2 sequence N-substituted on the threonamide amidic nitrogen with a (2S)-4-methyl-1-[(2R)-2-methyloxiran-2-yl]-1-oxopentan-2-yl group and with acetyl and meth l groups on the nitrogen of the isoleucine residue distal to the threonamide; a naturally occurring selective proteasome inhibitor with anti-inflammatory activity.일반 설명
Epoxomicin is a linear peptide consisting of a threonine or serine residue with α′, β′-epoxyketone?derived from leucine or a γ,δ-dehydroleucine. It is a natural product isolated from?Actinomyces?sp., and is a cell-permeable, potent, selective and irreversible proteasome inhibitor.에폭시마이신 준비 용품 및 원자재
원자재
준비 용품
에폭시마이신 공급 업체
글로벌( 104)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 |
sales@alabiochem.com | China | 888 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9338 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32715 | 60 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 |
sales@chemwish.com | CHINA | 10828 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
| Baoji Guokang Bio-Technology Co., Ltd. | 0917-3909592 13892490616 |
gksales1@gk-bio.com | China | 9327 | 58 |
| BOC Sciences | 16314854226; +16314854226 |
inquiry@bocsci.com | United States | 19743 | 58 |