U-57908;Rg 80267;RHC-80267;RXSVYGIGWRDVQC-UHFFFAOYSA-N;RHC-80267 - CAS 83654-05-1 - Calbiochem;1,6-bis(cyclohexyloximinocarbonyl)hexane;1,6-BIS(CYCLOHEXYLOXIMINOCARBONYLAMINO)HEXANE;1,6-Di(o-(carbamoyl)cyclohexanone oxime)hexane;1,6-bis(Cyclohexyloximinocarbonylamino)hexane, U 57908;O,O'-[1,6-Hexanediylbis(iminocarbonyl)]dioximecyclohexanone
눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
1,6-BIS(CYCLOHEXYLOXIMINOCARBONYLAMINO)헥산 C화학적 특성, 용도, 생산
용도
RHC-80267 is a selective inhibitor of DAG lipase, which plays an important role in the production of arachidonic acid.
일반 설명
Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells. Also inhibits glucose- and carbachol-induced insulin release from intact islets. An inhibitor of Angiotensin II (Cat. No. 05-23-0101) and ATP-induced synthesis of 6-keto-prostaglandin F1α.
생물학적 활성
Inhibitor of diacylglycerol lipase (IC 50 values are 1.1 and 4 μ M in rat cardiac myocytes and canine platelets respectively). Weakly inhibits phospholipases C and A 2 . Potentiates acetylcholine evoked relaxation in mesenteric arteries by the inhibition of cholinesterase activity (IC 50 = 4 μ M).
1,6-BIS(CYCLOHEXYLOXIMINOCARBONYLAMINO)헥산 준비 용품 및 원자재
