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TRIMIDOX

TRIMIDOX Structure
CAS No.
95933-74-7
Chemical Name:
TRIMIDOX
Synonyms
VF 233;TRIMIDOX;Trimidox Exclusive;MSLJYSGFUMYUDX-UHFFFAOYSA-N;N,3,4,5-TETRAHYDROXY-BENZENECARBOXIMIDAMIDE;Benzenecarboximidamide, N,3,4,5-tetrahydroxy-;4-[amino-(hydroxyamino)methylidene]-2,6-dihydroxycyclohexa-2,5-dien-1-one
CBNumber:
CB32446894
Molecular Formula:
C7H8N2O4
Molecular Weight:
184.15
MOL File:
95933-74-7.mol
Modify Date:
2023/5/21 10:59:17
Request For Quotation

TRIMIDOX Properties

storage temp. Store at -20°C
solubility ≤20mg/ml in DMSO;20mg/ml in dimethyl formamide
form crystalline solid

TRIMIDOX Chemical Properties,Uses,Production

Description

Ribonucleotide reductase, the rate-limiting enzyme for de novo DNA synthesis, is a common target for chemotherapy. Its increased activity in cancer cells is associated with malignant transformation and proliferation. Trimidox is a specific ribonucleotide reductase inhibitor that reduces levels of dGTP and dCTP in HL-60 cells, inducing apoptosis via activation of caspases without altering the cell cycle distribution. Trimidox inhibits growth of human promyelocytic leukemia HL-60 cells with an IC50 value of 35 μM.

Uses

Trimidox is a specific ribonucleotide reductase inhibitor.

TRIMIDOX Preparation Products And Raw materials

Raw materials

Preparation Products

TRIMIDOX Suppliers

Global( 16)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8736 58 Inquiry
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 China 8141 58 Inquiry
ApexBio Technology + 1-832-696-8203 United States 6254 58 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Shanghai Weiwei Biological Technology Co., Ltd. 021-55669583 18616258598 CHINA 4398 58 Inquiry
Shenzhen Xinbosheng Biological Technology Co., Ltd. 0755-26755892 CHINA 6164 58 Inquiry
Beijing Shengke Boyuan Biotechnology Co., Ltd. 010-62968438 CHINA 6011 58 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
Cayman Chemical Company 81
Shanghai Yifei Biotechnology Co. , Ltd. 58
MedBioPharmaceutical Technology Inc 58
ApexBio Technology 58
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Shanghai Weiwei Biological Technology Co., Ltd. 58
Shenzhen Xinbosheng Biological Technology Co., Ltd. 58
Beijing Shengke Boyuan Biotechnology Co., Ltd. 58

95933-74-7(TRIMIDOX)Related Search:

TRIMIDOX N-HYDROXY-3,4,5-TRIMETHOXY-BENZAMIDINE 4,N-DIHYDROXY-BENZAMIDINE
TRIMIDOX VF 233 Trimidox Exclusive MSLJYSGFUMYUDX-UHFFFAOYSA-N 4-[amino-(hydroxyamino)methylidene]-2,6-dihydroxycyclohexa-2,5-dien-1-one Benzenecarboximidamide, N,3,4,5-tetrahydroxy- N,3,4,5-TETRAHYDROXY-BENZENECARBOXIMIDAMIDE 95933-74-7