2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Structure
CAS No.
14665-75-9
Chemical Name:
2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE
Synonyms
Phenylephrine Impurity 26;2-AMino-3'-hydroxy-acetophenone HCl;2-amino-1-(3-hydroxy-phenyl)-ethanone;2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE;2-Amino-1-(3-hydroxyphenyl)ethanone Hydrochloride
CBNumber:
CB32467130
Molecular Formula:
C8H9NO2.ClH
Molecular Weight:
187.625
MOL File:
14665-75-9.mol
Modify Date:
2023/4/23 13:52:06

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Properties

Melting point 221–222°C
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form Solid
color Pale Beige to Brown

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Chemical Properties,Uses,Production

Preparation

Preparation by hydrolysis of m-(benzoyloxy)- a-amino-acetophenone hydrochloride (SM) (m.p. 202–205°) with refluxing 10% hydrochloric acid (quantitative yield), for 2 h (80%); ? with 37% hydrochloric acid in chlorobenzene at 90° for 3 h (90%). SM was obtained by reaction of hexamethylenetetramine with m-(benzoyloxy)- a-bromoacetophenone (m.p. 162°) in ethanol in the presence of 37% hydrochloric acid for 6 h at r.t. (75%).

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

2-AMINO-3'-HYDROXY-ACETOPHENONE HYDROCHLORIDE 2-AMino-3'-hydroxy-acetophenone HCl 2-Amino-1-(3-hydroxyphenyl)ethanone Hydrochloride 2-amino-1-(3-hydroxy-phenyl)-ethanone Phenylephrine Impurity 26 14665-75-9