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17- Phenyl Trinor Prostaglandin F2α Methyl Amide

17- Phenyl Trinor Prostaglandin F2α Methyl Amide Structure
CAS No.
155206-01-2
Chemical Name:
17- Phenyl Trinor Prostaglandin F2α Methyl Amide
Synonyms
Alvocidib Impurity 30;Bimatoprost Impurity 5;Bimatoprost Impurity E;Bimatoprost Methyl Amide;17-Phenyl Trinor Prostaglandin F2α Methyl Amide;17- Phenyl Trinor Prostaglandin F2α Methyl Amide;17-phenyl trinor Prostaglandin F2.alpha. methyl amide;17- Phenyl Trinor Prostaglandin F2α Methyl Amide (10mg/mL in Ethanol);(~{Z})-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide;5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-, (5Z)-
CBNumber:
CB32701218
Molecular Formula:
C24H35NO4
Molecular Weight:
401.54
MOL File:
155206-01-2.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:03:08

17- Phenyl Trinor Prostaglandin F2α Methyl Amide Properties

Boiling point 621.5±55.0 °C(Predicted)
Density 1.159±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO (Slightly), Ethanol
form Clear Colourless Solution
pka 14.25±0.20(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

17- Phenyl Trinor Prostaglandin F2α Methyl Amide Chemical Properties,Uses,Production

Description

17-phenyl trinor Prostaglandin F (17-phenyl trinor PGF) is a metabolically stable analog of PGF and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF. The ethyl amide of 17-phenyl trinor PGF bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor PGF methyl amide is an analog of bimatoprost. Its biological and toxicological properties have not been evaluated.

Uses

17-Phenyl Trinor Prostaglandin F2α-Methyl Amide is a stable analog of PGF2α and is a potent agonist of for the FP receptor. Analog of Bimatoprost (B386800), an antiglaucoma agent.

17- Phenyl Trinor Prostaglandin F2α Methyl Amide Preparation Products And Raw materials

Raw materials

Preparation Products

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17- Phenyl Trinor Prostaglandin F2α Methyl Amide 17-phenyl trinor Prostaglandin F2.alpha. methyl amide Bimatoprost Impurity 5 (~{Z})-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]-N-methylhept-5-enamide 17- Phenyl Trinor Prostaglandin F2α Methyl Amide (10mg/mL in Ethanol) 5-Heptenamide, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-, (5Z)- Bimatoprost Impurity E Bimatoprost Methyl Amide 17-Phenyl Trinor Prostaglandin F2α Methyl Amide Alvocidib Impurity 30 155206-01-2