(-)-Corey Lactone Diol

(-)-Corey Lactone Diol Structure
CAS No.
76704-05-7
Chemical Name:
(-)-Corey Lactone Diol
Synonyms
(3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxyMethyl)-hexahydrocyclopenta[b]furan-2-one;D-Corey lactone diol;Alvocidib Impurity 31;(+) COREY LACTONE DIOL;(+)-COREY LACTONE DIOL;Bimatoprost Impurity 8;Bimatoprost Impurity 2;Bimatoprost Impurity H;(-)-Corey lactone diol;(+) - Cortolactone diol
CBNumber:
CB0427364
Molecular Formula:
C8H12O4
Molecular Weight:
172.18
MOL File:
76704-05-7.mol
Modify Date:
2024/7/15 16:45:23

(-)-Corey Lactone Diol Properties

Melting point 114-118 °C(lit.)
alpha -44 º (C=1.4 IN MEOH)
Boiling point 406.6±25.0 °C(Predicted)
Density 1.365
storage temp. 2-8°C
pka 14.36±0.40(Predicted)
optical activity [α]20/D +44°, c = 2.3 in methanol
InChIKey VYTZWRCSPHQSFX-ZTYPAOSTSA-N
CAS DataBase Reference 76704-05-7

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  29322090

(-)-Corey Lactone Diol price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 453218 (3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one 98% 76704-05-7 250MG ₹17287.53 2022-06-14 Buy
Product number Packaging Price Buy
453218 250MG ₹17287.53 Buy

(-)-Corey Lactone Diol Chemical Properties,Uses,Production

Chemical Properties

Solid

Uses

(3aS,4R,5S,6aR)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one (Bimatoprost Impurity 8) is an impurity of Bimatoprost (B386800), an antiglaucoma agent. Bimatoprost is also a synthetic prostamide; structurally related to prostaglandin F2α.

(-)-Corey Lactone Diol Preparation Products And Raw materials

Raw materials

Preparation Products

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2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxymethyl)-,(3aS,4R,5S,6aR)- (3aS,4R,5S,6aR)-5-Hydroxy-4-(hydroxyMethyl)hexahydro-2H-cyclopenta[b]furan-2-one (3AS,4R,5S,6AR)-(+)-HEXAHYDRO-5-HYDROXY-4-(HYDROXYMETHYL)-2H-CYCLO-PENTA[B]FURAN-2-ONE (3as,4R,5S,6ar)-(+)-hexahydro-5-hydroxy-4-hoch2-2 (3AS,4R,5S,6AR)-(+)-HEXAHYDRO-5-HYDROXY- 4-HOCH2-2H-CYCLOPENTA(B)FURAN-2-ONE, 98% (3aR,5R,6R,6aS)-6-hydroxy-5-(hydroxymethyl)hexahydro-2H-cyclopenta[b]furan-2-one (3aS,4R,5S,6aR)-(+)-Hexahydro-5-hydroxy-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one 98% (3aS,4R,5S,6aR)-5-hydroxy-4-(hydroxymethyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-one (+)-COREY LACTONE DIOL 2H-Cyclopenta[b]furan-2-one,hexahydro-5-hydroxy-4-(hydroxylmethyl)-, (3aS,4R,5S,6aR)- (+) COREY LACTONE DIOL Bimatoprost Impurity 8 Bimatoprost Impurity 2 (+)-Corey lactone diol(For export only) Bimatoprost Impurity H (3aR,4S,5R,6aS)-5-hydroxy-4-(hydroxyMethyl)-hexahydrocyclopenta[b]furan-2-one D-Corey lactone diol Alvocidib Impurity 31 (+) - Cortolactone diol (-)-Corey lactone diol 76704-05-7 76704-08-7 33233-40-2 Asymmetric Synthesis Chiral Building Blocks Lactones Organic Building Blocks