VIRGINIAMYCIN M1

VIRGINIAMYCIN M1 Structure
CAS No.
21411-53-0
Chemical Name:
VIRGINIAMYCIN M1
Synonyms
Streptogramin A;C11299;PA 114A;Factor M;NSC 87432;NSC 244426;MIKAMYCIN A;Vernamycin A;STAPHYLOMYCIN;AVirginiaMyci
CBNumber:
CB3294594
Molecular Formula:
C28H35N3O7
Molecular Weight:
525.59
MOL File:
21411-53-0.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:04

VIRGINIAMYCIN M1 Properties

Melting point 165-167℃
alpha D20 -218° ( c = 0.34 in ethanol)
Boiling point 825.2±65.0 °C(Predicted)
Density 1.26±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility chloroform/methanol: soluble10mg/mL
form powder
pka 13.18±0.70(Predicted)
color yellow to tan
Stability Light Sensitive

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P280
WGK Germany  3
HS Code  29419090

VIRGINIAMYCIN M1 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) V2753 Virginiamycin M1 ≥95% (HPLC) 21411-53-0 5MG ₹48560.95 2022-06-14 Buy
Sigma-Aldrich(India) V2753 Virginiamycin M1 ≥95% (HPLC) 21411-53-0 10MG ₹56603.93 2022-06-14 Buy
Product number Packaging Price Buy
V2753 5MG ₹48560.95 Buy
V2753 10MG ₹56603.93 Buy

VIRGINIAMYCIN M1 Chemical Properties,Uses,Production

Chemical Properties

Light yellow powder

Uses

Ostreogrycin A (virginiamycin M1, streptogramin A) is the major component of the virginamycin complex. In the 1950s this complex was independently discovered so many times that the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts synergistically with the structurally unrelated cyclic depsipeptides, virginiamycin B (ostreogrycin B, streptogramin B) and virginiamycin S, to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A is highly active against Gram positive bacteria, particularly MRSA.

Definition

ChEBI: A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms includ ng methicillin-resistant Staphylococcus aureus.

Contact allergens

Like the other streptogramin, pristinamycin, virginiamycin is made of two subunits, virginiamycin S1 and virginiamycin M1. Dermatitis was quite common in people using the formerly available topical virginiamycin. Occupational dermatitis was observed in the pharmaceutical industry, in breeders, and in a surgeon who used topical virginiamycin on postoperative wounds (personal observation).

VIRGINIAMYCIN M1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826 China 25013 65 Inquiry
C11299 MikamycinA, Staphylomycin Antibiotic PA-114A1 Pristinamycin IIA Staphylomycin M1 Vernamycin A VirginiaMycin M1 DISCONTINUED MIKAMYCIN A STAPHYLOMYCIN VIRGINIAMYCINE VIRGINIAMYCIN M1 (3R,4R,5E,10E,12E,14S)- VirginiaMycin M1 (90%) AVirginiaMyci MikaMycin A, PristinaMycin IIA, StephyloMycin M1, StreptograMin A, Syncothrecin A, Synergistin A1, VirginiaMycin M1, VernaMycin A, 14752-2, E129A, PA 114A, 1745Z3A, 547C, Factor M Ostreogrycin A VirginiaMycin M1, froM StreptoMyces virginiae Antibiotic PA 114A Factor M Factor M (antibiotic) NSC 244426 NSC 87432 PA 114A Pristinamycin II Verginiamycin M1 Ostreogrycin A Antibiotic PA 114A NSC 244426 NSC 87432 Virginiamycin M1, 98%, from Streptomyces virginiae 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S)- Virginiamycin M1 Solution in Methanol,1000ug/ml Pristinamycin IIAQ: What is Pristinamycin IIA Q: What is the CAS Number of Pristinamycin IIA Q: What is the storage condition of Pristinamycin IIA Q: What are the applications of Pristinamycin IIA Streptogramin A Pristinamycin ⅡA Pristinamycin ⅡA Lepidophorin A Pristinamycin IIA|||Ostreogrycin A (12Z,6R,7R,8E,13E,15E,17S)-17-Hydroxy-6-isopropyl-7,15-dimethyl-32,33-dihydro-31H-5-oxa-11-aza-1(4,2)-oxazola-3(1,5)-pyrrolacycloicosaphane-8,13,15-triene-2,4,10,19-tetraone 21411-53-0 C28H35N3O7 Antibiotics A to Z Antibiotics Antibiotics T-Z BioChemical antibiotic Chiral Reagents Heterocycles Intermediates & Fine Chemicals Pharmaceuticals