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isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate

isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Structure
CAS No.
2053424-88-5
Chemical Name:
isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate
Synonyms
Tenofovir Alafenamide Impurity 16;isopropyl(((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate;isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate;isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate;isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate fumarate;D-Alanine, N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester
CBNumber:
CB33170369
Molecular Formula:
C21H29N6O5P
Molecular Weight:
476.47
MOL File:
2053424-88-5.mol
Modify Date:
2023/4/23 13:52:06
Request For Quotation

isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Properties

Melting point 134 - 138°C
Boiling point 640.4±65.0 °C(Predicted)
Density 1.39±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Methanol (Slightly, Sonicated)
pka 4.21±0.10(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic

isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Chemical Properties,Uses,Production

Uses

(R)-isopropyl 2-(((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate is an impurity of Tenofovir (T018500) which is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral.

isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Preparation Products And Raw materials

Raw materials

Preparation Products

isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Suppliers

Global( 33)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29888 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
China National Standard Pharmaceutical Corporation Limited +8615391658522 China 11927 58 Inquiry
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 18502726233; 18502726233 China 9808 58 Inquiry
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-010-52878169 15801002657 China 4921 58 Inquiry
Shandong WorldSun Biological Technology Co., Ltd. 0531-88723173 18596073690 China 4055 58 Inquiry
AF Biochem Co., Ltd. +86-028-60911900 13540204019 China 480 57 Inquiry
Cheng Du Micxy Chemical Co.,Ltd 028-85632863 18048500443 China 10476 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
Hubei Xinyang Medical Technology Co., Ltd 15347293736 15347293736 China 7888 58 Inquiry
Supplier Advantage
career henan chemical co 58
Chongqing Chemdad Co., Ltd 58
China National Standard Pharmaceutical Corporation Limited 58
Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd 58
Beijing Comparison Pharmaceutical Technology Co., Ltd 58
Shandong WorldSun Biological Technology Co., Ltd. 58
AF Biochem Co., Ltd. 57
Cheng Du Micxy Chemical Co.,Ltd 58
Nantong Hanfang Biotechnology Co. , Ltd. 58
Hubei Xinyang Medical Technology Co., Ltd 58

2053424-88-5(isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate)Related Search:

Diisopropyl Tenofovir FuMarate 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-[6-[[[[9-[(2R)-5-hydroxy-2,11-diMethyl-5-oxido-9-oxo-3,6,8,10-tetraoxa-5-phosphadodec-1-yl]-9H-purin-6-yl]aMino]Methyl]aMino]-9H-purin-9-yl]-1-Methylethoxy]Methyl]-, 1,9-bis(1-Methylethyl) ester, 5-ox P-[[(1S)-2-(6-AMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-phosphonic Acid Monoethyl Ester Tenofovir Alafenamide Impurity 30 Tenofovir Impurity H
(E)-9-(prop-1-en-1-yl)-9H-purin-6-amine Tenofovir Related Compound 6 TENOFOVIR-D6 Tenofovir Related Compound 1 (((((1-(6-aMino-9H-purin-9-yl)propan-2-yl)oxy)Methyl)phosphoryl)bis(oxy))bis(Methylene) isopropyl Methyl dicarbonate
isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir alafenamide hemifumarate Tenofovir Disopropyl Ethyl Diester Mono-POC Tenofovir FuMarate Salt ((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(((isopropoxycarbonyl)oxy)methoxy)phosphoryl)oxy)methyl dimethylcarbamate
Tenofovir disoproxil isopropyl ((R)-((((S)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate GS-7340 (fuMarate)
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isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate isopropyl (((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate Tenofovir Alafenamide Impurity 16 isopropyl ((R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate fumarate D-Alanine, N-[(R)-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester isopropyl(((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-D-alaninate 2053424-88-5