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PINOCEMBRIN

PINOCEMBRIN Structure
CAS No.
480-39-7
Chemical Name:
PINOCEMBRIN
Synonyms
Picembrin;PINOCEMBRIN;pinocemberin;dihydrochrysin;PINOCEMBRIN(RG);(+)-Pinocembrin;galanginflavanone;5,7-DIHYDROXYFLAVANONE;4H-1-BENZOPYRAN-4-ONE,2,3-DIH;5,7-DIHYDROXY-3'4'5'-FLAVANONE
CBNumber:
CB3378883
Molecular Formula:
C15H12O4
Molecular Weight:
256.25
MOL File:
480-39-7.mol
MSDS File:
SDS
Modify Date:
2023/5/25 18:01:06

PINOCEMBRIN Properties

Melting point 202 °C
Boiling point 511.1±50.0 °C(Predicted)
Density 1.386±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Soluble in ethanol and methan
form powder
pka 7.50±0.40(Predicted)
color White
LogP 3.225 (est)
EPA Substance Registry System 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2S)- (480-39-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Safety Statements  24/25
HS Code  29329990

PINOCEMBRIN Chemical Properties,Uses,Production

Description

Pinocembrin is a flavonoid that has been found in Eucalyptus, and has diverse biological activities. It induces apoptosis in, and inhibits the migration of, SKOV3 ovarian cancer cells when used at a concentration of 200 μM. Pinocembrin (5 mg/kg) reduces lesion volume, as well as brain microglial activation and production of IL-1β, IL-6, and TNF-α in a mouse model of collagenase-induced intracerebral hemorrhage (ICH). It prevents increases in plasma and kidney malondialdehyde (MDA) levels, glomeruli lobulation, mesangial expansion, and tubule vacuolization and occlusion, and it decreases hepatic cholesterol, triglyceride, and LDL levels in a rat model of diabetic nephropathy. Pinocembrin (20 and 50 mg/kg) reduces pulmonary edema, as well as neutrophil, lymphocyte, and macrophage infiltration in a mouse model of LPS-induced lung injury.

Chemical Properties

Solid

PINOCEMBRIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 219)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
Apeloa Pharmaceutical Co., Ltd. +86-0571-87635730 +8615858229168 China 1478 58 Inquiry

PINOCEMBRIN Spectrum

5,7-DIHYDROXYFLAVANONE 5,7-DIHYDROXY-3'4'5'-FLAVANONE 5,7-DIHYDROXY-2-PHENYL-CHROMAN-4-ONE PINOCEMBRIN (s)-2,3-dihydro-5,7-dihydroxy-2-phenyl-4h-1-benzopyran-4-one 3-dihydro-5,7-dihydroxy-2-phenyl-(s)-4h-1-benzopyran-4-on dihydrochrysin galanginflavanone PINOCEMBRIN(RG) 4H-1-BENZOPYRAN-4-ONE,2,3-DIH PinoceMbrin, froM Pinus cerebra (2S)-2-Phenyl-2,3-dihydro-5,7-dihydroxy-4H-1-benzopyran-4-one (2S)-2α-Phenyl-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one Picembrin (2S)-5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one 5,7-dihydroxy-2-phenyl-2,3-dihydro-4H-chromen-4-one Pinocembrin, 98%, from Pinus cerebra (2S)-5,7-Dihydroxy-2-phenylchroman-4-one 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-phenyl-, (2S)- (S)-5,7-Dihydroxy-2-Phenylchroman-4-One pinocemberin (+)-Pinocembrin Inhibitor,Bacterial,Autophagy,Reactive Oxygen Species,(+)-Pinocoembrin,inhibit,Pinocembrin 480-39-7 Inhibitors chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Flavanones