ChemicalBook > Product Catalog >API >Blood System Drugs >Anticoagulant and Antiplatelet Drugs >2-PHENYL-1,3-INDANDIONE
2-PHENYL-1,3-INDANDIONE
- CAS No.
- 83-12-5
- Chemical Name:
- 2-PHENYL-1,3-INDANDIONE
- Synonyms
- PHENINDIONE;PID;Indion;MTA2;Hedulin;2-Phenyl-1H-indene-1,3(2H)-dione;Indon;MTA1L1;Bindan;Indema
- CBNumber:
- CB3429480
- Molecular Formula:
- C15H10O2
- Molecular Weight:
- 222.24
- MOL File:
- 83-12-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/19 20:33:22
| Melting point | 144-148 °C(lit.) |
|---|---|
| Boiling point | 243.3 °C (0.3 mmHg) |
| Density | 1.1404 (rough estimate) |
| refractive index | 1.6600 (estimate) |
| Flash point | 208 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Very slightly soluble in water; slightly soluble in ethanol (96%) and in ether. Solutions are yellow to red. |
| form | powder to crystal |
| pka | pKa 4.09(H2O,t =25,I=0.1) (Uncertain) |
| color | White to Light yellow |
| Merck | 14,7234 |
| CAS DataBase Reference | 83-12-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H317 | |||||||||
| Precautionary statements | P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P310-P321-P330-P405-P501 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-43 | |||||||||
| Safety Statements | 36/37/39-45 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NK6125000 | |||||||||
| HS Code | 2914.39.9000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Hazardous Substances Data | 83-12-5(Hazardous Substances Data) | |||||||||
| NFPA 704 |
|
2-PHENYL-1,3-INDANDIONE Chemical Properties,Uses,Production
Description
Phenindione is an anticoagulant and vitamin K antagonist. It inhibits the reduction of vitamin K1 epoxide to vitamin K1 by vitamin K1 epoxide reductase in rat liver homogenates in a concentration-dependent manner. In vivo, phenindione (500 mg/kg) inhibits prothrombin synthesis and conversion of vitamin K1 epoxide to vitamin K1 in rats by 50 and 57%, respectively. Dietary administration of phenindione (4 mg/kg per day) inhibits aortic atherosclerosis or intracardial thrombosis in rat models of diet-induced atherosclerosis or intravascular thrombosis, respectively.
Chemical Properties
light yellow fluffy fine flakes
Uses
Oral anticoagulant (indanedione).
Purification Methods
Crystallise the dione from EtOH (m 156o) or CHCl3 (m 148-150o). [Beilstein 7 H 808, 7 III 4100, 7 IV 2570.]
2-PHENYL-1,3-INDANDIONE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 111)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
| Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | China | 8806 | 58 | Inquiry |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | China | 12832 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | China | 29793 | 60 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 32161 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34563 | 58 | Inquiry |
| Henan Alfa Chemical Co., Ltd | China | 11663 | 58 | Inquiry |
83-12-5(2-PHENYL-1,3-INDANDIONE)Related Search:
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AURORA KA-4422
2-PHENYL-1,3-INDANDIONE
Phenyline
Phenyllin
Pindione
Rectadione
Theradione
Thrombasal
Tromazal
Trombol
Phenindione (250 mg)
Phenindione(Rectadione)
ANTI-PID/MTA2(C-TERMINAL) antibody produced in rabbit
Metastasis-associated 1-like 1
Metastasis-associated protein MTA2
MTA1L1
2-PHENYL-1,3-INDANEDIONE
2-PHENYL-1,3-DIKETOHYDRINDENE
2-PHENYL-1H-INDEN-1,3(2H)-DIONE
PHENYLINDIONE
PHENINDONE
Phenylindandione
2-Phenyl-1H-inden-1,3(2H)-dione,99%
1,3(2H)-Indenedione, 2-phenyl-
1,3-Indandione, 2-phenyl-
1,3-Indandione,2-phenyl-
1H-Indene-1,3(2H)-dione, 2-phenyl-
1H-Indene-1,3(2H)-dione,2-phenyl-
2-fenyloindandion-1,3
2-phenyl-1h-indene-3(2h)-dione
2-phenyl-3-indandione
2-Phenyl-indan-1,3-dione
2-Phenylindan-1,3-dione
2-phenylindan-1-3-dione
2-Phenylindandione
Athrombon
Bindan
Cronodione
Danedion
Danilon
Danilone
Diadilan
Dindevan
Dineval
Diophindane
Emandion
Emandione
Eridione
Fenhydren
Fenilin
Fenindion
heducin
Hemolidione
Indema
Indon
Phenhydren
Phenillin
Phenindion