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ChemicalBook > Product Catalogue >API >Blood System Drugs >Anticoagulant and Antiplatelet Drugs >2-PHENYL-1,3-INDANDIONE

2-PHENYL-1,3-INDANDIONE

2-PHENYL-1,3-INDANDIONE Structure
  • ₹4600
  • Product name: 2-PHENYL-1,3-INDANDIONE
  • CAS: 83-12-5
  • MF: C15H10O2
  • MW: 222.24
  • EINECS:201-454-4
  • MDL Number:MFCD00003782
  • Synonyms:AURORA KA-4422;2-PHENYL-1,3-INDANDIONE;Phenyline;Phenyllin;Pindione;Rectadione;Theradione;Thrombasal
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Selected condition:

Brand

  • TCI Chemicals (India)

Package

  • 25G
  • ManufacturerTCI Chemicals (India)
  • Product numberP1029
  • Product description2-Phenyl-1,3-indandione min. 98.0 %
  • Packaging25G
  • Price₹4600
  • Updated2022-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) P1029 2-Phenyl-1,3-indandione min. 98.0 % 25G ₹4600 2022-05-26 Buy

Properties

Melting point :144-148 °C(lit.)
Boiling point :243.3 °C (0.3 mmHg)
Density :1.1404 (rough estimate)
refractive index :1.6600 (estimate)
Flash point :208 °C
storage temp. :Inert atmosphere,Room Temperature
solubility :Very slightly soluble in water; slightly soluble in ethanol (96%) and in ether. Solutions are yellow to red.
form :powder to crystal
pka :pKa 4.09(H2O,t =25,I=0.1) (Uncertain)
color :White to Light yellow
Merck :14,7234
CAS DataBase Reference :83-12-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Phenindione is an anticoagulant and vitamin K antagonist. It inhibits the reduction of vitamin K1 epoxide to vitamin K1 by vitamin K1 epoxide reductase in rat liver homogenates in a concentration-dependent manner. In vivo, phenindione (500 mg/kg) inhibits prothrombin synthesis and conversion of vitamin K1 epoxide to vitamin K1 in rats by 50 and 57%, respectively. Dietary administration of phenindione (4 mg/kg per day) inhibits aortic atherosclerosis or intracardial thrombosis in rat models of diet-induced atherosclerosis or intravascular thrombosis, respectively.

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