ChemicalBook > Product Catalog >Organic Chemistry >Organic fluorine compound >Fluorobenzonitrile series >5-Bromo-2-fluorobenzonitrile

5-Bromo-2-fluorobenzonitrile

CAS No.: 179897-89-3

Chemical Name:: 5-Bromo-2-fluorobenzonitrile

Synonyms: 2-Fluoro-5-bromobenzonitrile;Olapali impurity 6;Olapali impurity 17;2- fluorine-5-broMoxynil;5-BROMO-2-FLUOROBENZONITRILE;2-Flouro-5-bromobenzonitrile;2-Fliuoro-5-broMo Benzonitrile;Benzonitrile, 5-broMo-2-fluoro-;5-Bromo-2-fluorobenzonitrile98%;5-Bromo-2-fluorobenzonitrile >

CBNumber:: CB3431412

Molecular Formula:: C7H3BrFN

Molecular Weight:: 200.01

MOL File:: 179897-89-3.mol

MSDS File:: SDS

Modify Date:: 2024/10/28 16:48:35

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5-Bromo-2-fluorobenzonitrile Properties

Melting point	76-81 °C
Boiling point	220.4±20.0 °C(Predicted)
Density	1.7286 (rough estimate)
refractive index	1.5320 (estimate)
storage temp.	Sealed in dry,Room Temperature
solubility	soluble in Methanol
form	powder to crystal
color	White to Light yellow to Light orange
BRN	7701063
InChI	InChI=1S/C7H3BrFN/c8-6-1-2-7(9)5(3-6)4-10/h1-3H
InChIKey	GYCNHFWRPJXTSB-UHFFFAOYSA-N
SMILES	C(#N)C1=CC(Br)=CC=C1F
CAS DataBase Reference	179897-89-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338

Hazard Codes

Xn,T,Xi

Risk Statements

36/37/38-20/21/22

Safety Statements

36/37/39-26-22-36

RIDADR

3439

WGK Germany

Hazard Note

Toxic

HazardClass

6.1

PackingGroup

III

HS Code

29269090

NFPA 704

	1
2		0

5-Bromo-2-fluorobenzonitrile price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	465259	5-Bromo-2-fluorobenzonitrile 97%	179897-89-3	1G	₹1558.8	2022-06-14	Buy
Sigma-Aldrich(India)	465259	5-Bromo-2-fluorobenzonitrile 97%	179897-89-3	5G	₹3344.93	2022-06-14	Buy
TCI Chemicals (India)	B2425	5-Bromo-2-fluorobenzonitrile min. 98.0 %	179897-89-3	5G	₹2600	2022-05-26	Buy
TCI Chemicals (India)	B2425	5-Bromo-2-fluorobenzonitrile min. 98.0 %	179897-89-3	25G	₹8500	2022-05-26	Buy
ALFA India	ALF-A16113-14	5-Bromo-2-fluorobenzonitrile, 98%	179897-89-3	25g	₹10842	2022-05-26	Buy

Product number	Packaging	Price	Buy
465259	1G	₹1558.8	Buy
465259	5G	₹3344.93	Buy
B2425	5G	₹2600	Buy
B2425	25G	₹8500	Buy
ALF-A16113-14	25g	₹10842	Buy

5-Bromo-2-fluorobenzonitrile Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder or crystals

Uses

5-Bromo-2-fluorobenzonitrile may be used for the preparation of the following compounds:

(E)-5-(2-cyclopropylvinyl)-2-fluorobenzonitrile and methyl-3-amino-5-bromobenzo[b]thiophene-2-carboxylate
(S)-[2-[5-(3-cyano-4-fluoro-phenyl)-pyridin-3-yloxy]-1-(1H-indol-3-ylmethyl)-ethyl]-carbamic acid tert-butyl ester
4-fluoro-3-cyano-3′-tributyltinbenzhydrol
4-fluoro-3-cyano-3′-iodobenzhydrol

Synthesis

5-Bromo-2-fluorobenzonitrile is the key intermediate of the synthetic antigout drug Febuxostat. The synthesis method comprises the following steps: reacting o-fluorobenzoyl chloride with ammonia water to obtain o-fluorobenzamide; then generating o-fluorobenzonitrile under the action of a dehydration reagent; and finally, in 75-90% sulfuric acid, brominating with dibromohydantoin to obtain 5-bromo-2-fluorobenzonitrile. The synthesis method is simple and easy to implement, mild in conditions, low in production cost, and causes no wastewater discharge.

5-Bromo-2-fluorobenzonitrile Preparation Products And Raw materials

Raw materials

2-MERCAPTOPYRIMIDINE-4,6-DIOL

Preparation Products

3-Cyano-4-fluorobenzeneboronic acid 4-BROMO-2-HYDROXYBENZONITRILE Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate 2-(tetrahydro-2H-pyran-4-yloxy)-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)benzonitrile 2-FLUORO-5-METHOXYBENZONITRILE

5-BroMo-2-(pyrrolidin-1-yl)benzonitrile 3-(3-CYANO-4-FLUOROPHENYL)-1-PROPENE 5-(5-BroMo-2-fluorophenyl)-2H-tetrazole 5-broMo-2-(tetrahydro-2H-pyran-4-yloxy)benzonitrile 5-Bromo-2-mercapto-benzonitrile

1,7-DIBROMO-3-ISOQUINOLINAMINE 5-BroMo-2-(piperidin-1-yl)benzonitrile 5-BROMO-1H-INDAZOL-3-AMINE

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5-Bromo-2-fluorobenzonitrile Suppliers

Global( 381)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
BTC pharm India	+918790379245	AndhraPradesh, India	1262	58	Inquiry
GLR Innovations	+91 9891111994	New Delhi, India	4535	58	Inquiry
SURVIVAL TECHNOLOGIES LIMITED	+91 8108285261	Gujarat, India	294	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3753	58	Inquiry
Suven Pharmaceuticals Limited	+91-91-40-23541142 +91-4023541142	Telangana, India	218	58	Inquiry
Neogen Chemicals Ltd	+91-9619496467 +91-8657984687	Maharashtra, India	56	58	Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd.	+91-26463395 +91-7926462688	Gujarat, India	1615	58	Inquiry
BASR Fine Chemicals Pvt. Ltd.	+91-9848230391 +91-9848230391	Telangana, India	908	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6768	58	Inquiry
Alfa Aesar	1 800 209 7001	Maharashtra, India	6905	58	Inquiry

Supplier	Advantage
BTC pharm India	58
GLR Innovations	58
SURVIVAL TECHNOLOGIES LIMITED	58
JSK Chemicals	58
Suven Pharmaceuticals Limited	58
Neogen Chemicals Ltd	58
Rivashaa Agrotech Biopharma Pvt. Ltd.	58
BASR Fine Chemicals Pvt. Ltd.	58
TCI Chemicals (India) Pvt. Ltd.	58
Alfa Aesar	58

179897-89-3(5-Bromo-2-fluorobenzonitrile)Related Search:

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DBDCB Bromoxynil octanoate Transfluthrin 5-bromo-3-fluorobenzonitrile 2-Fluorobenzonitrile

4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one PIPERAZINE DIHYDROCHLORIDE 3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid

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Benzonitrile, 5-broMo-2-fluoro- 2- fluorine-5-broMoxynil 2-Fliuoro-5-broMo Benzonitrile 5-Bromo-2-fluorobenzonitrile,97% 5-BROMO-2-FLUOROBENZONITRILE 5-Bromo-2-fluorobenzonitrile 98% 5-Bromo-2-fluorobenzonitrile98% 5-Bromo-2-fluorobenzonitrile > 5-Bromo-2-fluorobenzonitrile (Olaparib Impurity) 2-Fluoro-5-bromobenzonitrile Olapali impurity 6 Olapali impurity 17 2-Flouro-5-bromobenzonitrile 179897-89-3 Cyanides/Nitriles Organic Building Blocks Nitrogen Compounds ARYL HALIDE Building Blocks C6 to C7 cyanide| alkyl bromide| alkyl Fluorine Fluorine series Febuxostat Aromatic Nitriles Nitrile Miscellaneous Bromine Compounds Fluorine Compounds Nitriles C6 to C7 Cyanides/Nitriles Nitrogen Compounds Fluorobenzene