Zaltoprofen
- CAS No.
- 89482-00-8
- Chemical Name:
- Zaltoprofen
- Synonyms
- Peon;CN-100;Soreton;Zaltoprofen;Zaltoprofene;Zaltoprofeno;Zaltoprofenum;Unii-H8635ng3py;Zaltoprofen USP/EP/BP;CN 100 (antiphlogistic)
- CBNumber:
- CB3441374
- Molecular Formula:
- C17H14O3S
- Molecular Weight:
- 298.36
- MOL File:
- 89482-00-8.mol
- Modify Date:
- 2024/3/19 15:37:50
Zaltoprofen Chemical Properties,Uses,Production
Description
Zaltoprofen is a potent non-steroidal antiinflammatory drug (NSAID) with analgesic activity. In rats and mice, zaltoprofen is reported to be equipotent or superior to other NSAlDs in bradykinin-induced pain, acetic acid-induced writhing, carrageenan-induced hyperalgesia, and in several other experimental models of analgesia. It acts by selectively suppressing the production of prostaglandins at the inflammatory site and not in other organs such as stomach and kidney, therefore, has remarkably low gastric side effects that are associated with conventional antiinflammatory agents.
Chemical Properties
Off-White to Pale Yellow Crystalline Solid
Uses
Anti-inflammatory activity resides in (S)-enantiomer
Synthesis
The cyclization of 5-(1- cyanoethyl)-2-(phenylthio)phenylacetic acid in presence of polyphosphoric acid at 120 ℃ gives 2-(10-oxo-10,11-dihydrodibenzo[b,f ]thiepin- 2-yl)propionitrile, which is then hydrolyzed with KOH in refluxing ethanol – water to zaltoprofen.
Zaltoprofen Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Veer Pharmachem | +91-02645661117 +91-9879471589 | Gujarat, India | 39 | 58 | Inquiry |
| Nivika Chemo Pharma Pvt Ltd | +91-9824176501 +91-9824176501 | Gujarat, India | 15 | 58 | Inquiry |
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
| Alfa Omega Pharma | +91-8050045945 +91-9972665399 | Maharashtra, India | 126 | 58 | Inquiry |
| Sibram Pharmaceutical | +91-8655777550 +91-8655777550 | Maharashtra, India | 244 | 58 | Inquiry |
| Apex Distributors | 08048372628Ext 317 | Mumbai, India | 14 | 58 | Inquiry |
| OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | China | 305 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29797 | 60 | Inquiry |
| Supplier | Advantage |
|---|---|
| Veer Pharmachem | 58 |
| Nivika Chemo Pharma Pvt Ltd | 58 |
| Hetero Drugs Limited | 58 |
| Ralington Pharma | 58 |
| Alfa Omega Pharma | 58 |
| Sibram Pharmaceutical | 58 |
| Apex Distributors | 58 |
| OCEAN TRADING CORPORATION | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | 58 |
| Capot Chemical Co.,Ltd. | 60 |