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Pipecuronium bromide

CAS No.: 52212-02-9

Chemical Name:: Pipecuronium bromide

Synonyms: Pipecuronium;Arduan;Ardtm;D00764;RGH-1106;Arduan (tn);PIPECURIUM BROMIDE;Pipecuriurn Brmnide;PIPECURINIUM BROMIDE;pipecuronium bromide

CBNumber:: CB1854855

Molecular Formula:: C35H62Br2N4O4

Molecular Weight:: 762.69918

MOL File:: 52212-02-9.mol

Modify Date:: 2024/4/9 13:47:46

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Pipecuronium bromide Properties

Melting point	262-264° (dec)
alpha	D25 +8.1° (c = 1 in water)
storage temp.	Store at -20°C
solubility	DMSO, Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Off-White
CAS DataBase Reference	52212-02-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H312-H331-H300
Precautionary statements	P264-P270-P301+P310-P321-P330-P405-P501-P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P311-P321-P403+P233-P405-P501
Toxicity	LD50 in mice, rats (mg/kg): 29.7, 172.6 i.v.; 70.6, 449.6 i.p.; 60.5, 455.8 s.c. (Kárpáti, Biro)

Pipecuronium bromide Chemical Properties,Uses,Production

Uses

Pipecuronium Bromide is a muscle relaxant and an anaesthesia used in patients undergoing coronary artery bypass graft surgery.

General Description

Pipecurium bromide, 4,4 -(3 ,17 -dihydroxy-5 -androstan-2 ,16 -ylene)bis(1,1-dimeth-ylpiperazinium)dibromide diacetate (Arduan), is anondepolarizing muscle relaxant similar, both chemicallyand clinically, to pancuronium bromide. It is a long-actingdrug indicated as an adjunct to anesthesia and in patients undergoingmechanical ventilation.

Pharmacology

Pipecuronium bromide, an analogue of pancuronium, was developed in Hungary in 1980 and is marketed in Eastern Europe and the United S tates. The intubating dose is 0.07 mg kg–1. The onset time and time to recovery from block are similar to those of pancuronium, and excretion of the drug through the kidneys is significant (66%). In contrast to pancuronium, pipecuronium produces marked cardiovascular stability, having no vagolytic or sympathomimetic effects. It may therefore be useful during major surgery in patients with cardiac disease.

Pipecuronium bromide Preparation Products And Raw materials

Raw materials

Erythromycin Estolate Perbenzoic acid Hexane Sodium borohydride Chloroform

Tetrahydrofuran Androstene-2-ene-17-one Magnesium sulfate Isopropenyl acetate

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Preparation Products

Pipecuronium bromide Suppliers

Global( 96)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd	+91-172-5066494	Haryana, India	6773	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	China	20374	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29797	60	Inquiry
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	China	21677	55	Inquiry
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	China	10246	58	Inquiry
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	China	6387	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
career henan chemical co	+86-0371-86658258 15093356674;	China	29826	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	United States	19892	58	Inquiry

Supplier	Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd	58
CLEARSYNTH LABS LTD.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
Shenzhen Nexconn Pharmatechs Ltd	58
Xiamen AmoyChem Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
TargetMol Chemicals Inc.	58

52212-02-9(Pipecuronium bromide)Related Search:

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pipecuronium bromide 4,4'-((2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetyloxy)androstane-2,16-diyl)bis(1,1-dimethyl-piperazinium) dibromide 4,4'-[(2beta,3alpha,5alpha,16beta,17beta)-3,17-bis(acetoxy)androstane-2,16-diyl]bis[1,1-dimethylpiperazinium] dibromide PIPECURIUM BROMIDE PIPECURINIUM BROMIDE 4，4’-[(2β，3α，5α，16β，17β)-3，17-Bis(acetoxy)andrc~tane-2，16-diyl]bis(1，1-dimethylpiperazinium)dibromide Ardtm Pipecuriurn Brmnide RGH-1106 [(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-17-acetyloxy-2,16-bis(4,4-dimethyl-2,3,5,6-tetrahydropyrazin-1-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate dibromide Androstane, piperazinium deriv. Piperazinium, 4,4'-[(2b,3a,5a,16b,17b.)-3,17-bis(acetyloxy)androstane-2,16-diyl]bis[1,1-dimethyl-, bromide (1:2) Arduan (tn) D00764 Pipecuronium bromide (usan/inn) Pipecuronium (Pipecurium)Bromide PipecuroniuM BroMide(RGH-1106) WGBNBQWFBCPQRF-UHFFFAOYSA-N Muscle relaxant Pipecuronium bromide /In stock CAS NO.52212-02-9 CAS NO.52212-02-9 acetic acid [17-acetyloxy-2,16-bis(4,4-dimethyl-1-piperazin-4-iumyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] ester dibromide Pipecuronium bromide USP/EP/BP 4,4'-((2beta,3alpha,5alpha,16beta,17beta)-3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1,1-dimethyl-piperazinium) dibromide Pipecuronium Arduan 4,4'-((2beta,3alpha,5alpha,16beta,17beta)-3,17-Bis(acetyloxy)androstane-2,16-diyl)bis(1,1-dimethyl-piperazinium) dibromide 52212-02-9