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Angiotensin II human acetate

CAS No.: 68521-88-0

Chemical Name:: Angiotensin II human acetate

Synonyms: HYPERTENSIN II;Ang II acetate;DRVYIHPF acetate;ANGIOTENSIN , HUMAN;Angiotensin Ⅱ, human;Angiotensin II xacetate;ANGIOTENSIN II ACETATE SALT;ANGIOTENSIN II ACETATE HUMAN;angiotensin ii human acetate;ANGIOTENSIN II, HUMAN, SYNTHETIC

CBNumber:: CB3454530

Molecular Formula:: C52H75N13O14

Molecular Weight:: 1106.25

MOL File:: 68521-88-0.mol

MSDS File:: SDS

Modify Date:: 2024/5/16 14:26:18

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Angiotensin II human acetate Properties

storage temp.	−20°C
solubility	H₂O: 25 mg/mL, clear, colorless
form	powder
color	orange

SAFETY

Risk and Safety Statements

WGK Germany	3
F	3-10

Angiotensin II human acetate Chemical Properties,Uses,Production

Uses

Angiotensin II human acetate (Angiotensin II acetate) is a vasoconstrictor that mainly acts on the AT1 receptor. It stimulates sympathetic nervous stimulation and increases aldosterone biosynthesis and renal actions. It also induces the growth of vascular smooth muscle cells. It increases collagen type I and III synthesis in fibroblasts, weakening the vascular wall, myocardium, and fibrosis. Angiotensin II human acetate also induces apoptosis.

in vitro

Most of the known actions of Angiotensin II (Ang II) human acetate are mediated by AT1 receptors; the AT2 receptor regulates blood pressure and renal function. Angiotensin II human acetate raises blood pressure (BP) through several actions, the most important ones being vasoconstriction, sympathetic nervous stimulation, increased aldosterone biosynthesis, and renal actions. Other Angiotensin II human acetate actions include induction of growth, cell migration, and mitosis of vascular smooth muscle cells, increased synthesis of collagen type I and III in fibroblasts, leading to thickening of the vascular wall and myocardium, and fibrosis. These actions are mediated by type 1 Ang II receptors (AT1). Angiotensin II (1 nM) induces the expression of LOX-1 and VEGF and enhances capillary formation from human coronary endothelial cells in Matrigel assay. Angiotensin II -mediated expression of LOX-1 and VEGF, capillary formation, intracellular reactive oxygen species generation, and phosphorylation of p38 as well as p44/42 mitogen-activated protein kinases were suppressed by anti-LOX-1 antibody, nicotinamide-adenine dinucleotide phosphate oxidase inhibitor apocynin and the Ang II type 1 receptor blocker Losartan, but not by the Ang II type 2 receptor blocker PD123319.

Angiotensin II human acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Angiotensin II human acetate Suppliers

Global( 91)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	China	12453	58	Inquiry
Dorne Chemical Technology co. LTD	+86-86-13583358881 +8618560316533	China	3146	58	Inquiry
Hebei Xinsheng New Material Technology Co., LTD.	+86-16632316109	China	1090	58	Inquiry
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	China	616	58	Inquiry
Shanghai Affida new material science and technology center	+undefined15081010295	China	114	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
SIMAGCHEM CORP	+86-13806087780	China	17367	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	24607	58	Inquiry

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Dorne Chemical Technology co. LTD	58
Hebei Xinsheng New Material Technology Co., LTD.	58
Nantong Guangyuan Chemicl Co,Ltd	58
Shanghai Affida new material science and technology center	58
ATK CHEMICAL COMPANY LIMITED	60
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
SIMAGCHEM CORP	58
Dideu Industries Group Limited	58

68521-88-0(Angiotensin II human acetate)Related Search:

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ANGIOTENSIN III, HUMAN Inositol ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT (2S)-1-[(2S)-2-Amino-3-(3H-imidazol-4-yl)propanoyl]pyrrolidine-2-carboxamide Angiotensin

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ANGIOTENSIN II ACETATE SALT ANGIOTENSIN II HUMAN ACETATE SALT ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT HYPERTENSIN II ANGIOTENSIN II ACETATE HUMAN ANGIOTENSIN II-FLUORESCEIN SYNTHETIC >81 % ANGIOTENSIN II, MASS SPEC STANDARD ANGIOTENSIN II, HUMAN, SYNTHETIC angiotensin ii human acetate ANGIOTENSIN , HUMAN Angiotensin Ⅱ, human angiotensin II, 5-L-isoleucine-, acetate (salt) 5-L-Isoleucineangiotensin II acetate Human angiotensin II acetate salt Angiotensin II huMan acetate hydrate ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACETATE SALT USP/EP/BP Angiotensin II xacetate Ang II acetate DRVYIHPF acetate Angiotensin Receptor,Inhibitor,Angiotensin II human,inhibit,Angiotensin II,Ang II,DRVYIHPF,Apoptosis,Angiotensin II human acetate (2S,5S,8S,11S,14S,17S)-2-((1H-Imidazol-5-yl)methyl)-17-amino-5-((S)-sec-butyl)-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-isopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid xacetic acid 68521-88-0 C52H75N13O14 C50H71N13O12xC2H4O2 Analytical Standards Application Index Biochemicals and Reagents Alphabetic Albumin and other protein conjugates Analytical Chromatography Product Catalog BioChemical Cell Signaling Enzymes Fluorescent Conjugates Fluorescent Probes, Labels, Particles and Stains Chymase and Related Products Enzymes, Inhibitors, and Substrates PON - PT SignalTransduction Peptide Receptors Peptide