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ANGIOTENSIN II, HUMAN

ANGIOTENSIN II, HUMAN Structure
CAS No.
4474-91-3
Chemical Name:
ANGIOTENSIN II, HUMAN
Synonyms
ANGIOTENSIN II;Ang II;DRVYIHPF;TY-10721;AngiotensinⅡ;ANGIOTENSIN-2;H-DRVYIHPF-OH;angiotensin renin;ANTI-ANGIOTENSIN II;ile(5)-angiotensini
CBNumber:
CB0338057
Molecular Formula:
C50H71N13O12
Molecular Weight:
1046.2
MOL File:
4474-91-3.mol
MSDS File:
SDS
Modify Date:
2024/6/5 17:10:12

ANGIOTENSIN II, HUMAN Properties

Boiling point 809.08°C (rough estimate)
Density 1.1257 (rough estimate)
refractive index 1.6700 (estimate)
RTECS BW2165000
storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility insoluble in DMSO; insoluble in EtOH; ≥100.2 mg/mL in H2O
form Powder
pka pK1: 10.37 (25°C)
color orange
Water Solubility Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml).
Sequence H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Stability Hygroscopic
InChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N

SAFETY

Risk and Safety Statements

WGK Germany  3

ANGIOTENSIN II, HUMAN price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A9525 Angiotensin II human ≥93% (HPLC), powder 4474-91-3 1MG ₹3897 2022-06-14 Buy
Sigma-Aldrich(India) A9525 Angiotensin II human ≥93% (HPLC), powder 4474-91-3 5MG ₹8129.58 2022-06-14 Buy
Sigma-Aldrich(India) A9525 Angiotensin II human ≥93% (HPLC), powder 4474-91-3 5X1MG ₹14289 2022-06-14 Buy
Sigma-Aldrich(India) A9525 Angiotensin II human ≥93% (HPLC), powder 4474-91-3 10MG ₹14960.15 2022-06-14 Buy
Sigma-Aldrich(India) A9525 Angiotensin II human ≥93% (HPLC), powder 4474-91-3 25MG ₹26856.83 2022-06-14 Buy
Product number Packaging Price Buy
A9525 1MG ₹3897 Buy
A9525 5MG ₹8129.58 Buy
A9525 5X1MG ₹14289 Buy
A9525 10MG ₹14960.15 Buy
A9525 25MG ₹26856.83 Buy

ANGIOTENSIN II, HUMAN Chemical Properties,Uses,Production

Description

It is known that tumor tissues including metastatic lymph nodes are composed of newly growing vessels which lack blood flow autoregulation and are influenced only secondarily by the responding somatic vessels. Human angiotensin II (AT II). a vasopressor, was introduced in Japan to improve the efficacy of systemic chemotherapy. In patients with various advanced cancers, i.v. infusion of AT II to achieve a mean blood pressure of 1.5 times of baseline (but not over 150 mm Hg) followed by a bolus injection of conventional cytotoxic agents increases blood flow 5-7 fold in tumor tissues and therefore, increases drug delivery to the target tissue resulting in enhanced chemotherapeutic effects. This induced-hypertension chemotherapy regimen can be performed safely with minimal side effects.

Uses

Cardiopulmonary resuscitation - not yet an approved application

General Description

Functions in blood pressure maintenance. Stimulates the release of aldosterone from the adrenal gland. Has strong vasoconstrictive effects. Increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase. Activates JAK2 in smooth muscle cells. Activates p125FAK and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. Also activates pp60c-src in vascular smooth muscle cells. Inhibits adenylate cyclase activity in spontaneously hypertensive rats.

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[ILE5]-ANGIOTENSIN 2 HYPERTENSION II HUMAN L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH FLUORESCEIN-NHCS-NH-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O ANGIOTENSIN II, HUMAN ANGIOTENSIN II (HUMAN) ACOH 4H2O ANGIOTENSIN II, [ASN1,VAL5] ANGIOTENSIN II, DES-ASP1-[ILE8] ANGIOTENSIN II - FLUORESCEIN RBIOPROBE(TM) ANTI-ANGIOTENSIN II ANTI-ANGIOTENSIN II, HUMAN 5-l-isoleucine-angiotensini 5-l-isoleucineangiotensinii angiotensinii(mouse) ile(5)-angiotensini ANGIOTENSIN-2 H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt ProteoMassTM Angiotensin II MALDI-MS Standard Angiotensin II-fluorescein human ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ACOH 4H2O ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE ANGIOTENSIN II, [SAR1,ALA8] ANGIOTENSIN II, [SAR1,ILE8] ANGIOTENSIN II, [SAR1,THR8] Vals-hypertensin-II-Asp-β-amide [Ile5]angiotensin II Angiotensin II【guinea pig】 Angiotensin II【rabbit】 TY-10721 Angiotensin 2 (Human Type) H-DRVYIHPF-OH ANGIOTENSIN II, HUMA HuMan angiotension Ⅱ Relative Molecular Weight Angiotensin II, 5-L-isoleucine- Angiotensin Acetate II Angiotensin II, Ang II ANGIOTENSIN II, HUMAN, OCTAPEPTIDE ANGIOTENSIN II, [VAL5] ProteoMass? Angiotensin II MALDI-MS Standard ANGIOTENSIN 2; ANGIOTENSIN RENIN; ANGIOTENSIN RECEPTOR; angiotensin renin HYPERTENSIN II;ANG II Angiotensin II trifluoroacetate salt H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH trifluoroacetate salt Angiotensin II, Human - CAS 4474-91-3 - Calbiochem ANGIOTENSIN II;HYPERTENSIN II;ANG II;DRVYIHPF Angiotensin?II impurity ANGIOTENSIN II, HUMAN USP/EP/BP 4474-91-3 ANGIOTENSIN II, HUMAN DRVYIHPF Ang II ANGIOTENSIN II (2S,5S,8S,11S,14S,17S)-2-((1H-Imidazol-5-yl)methyl)-17-amino-5-((S)-sec-butyl)-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-isopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid Angiotensin II human,Apoptosis,Angiotensin Receptor,Inhibitor,inhibit Rabbit Anti-Angiotensin II antibody Peptide Angiotensin 2 Andangiotensin II Human Acetate AngiotensinⅡ