ANGIOTENSIN II, HUMAN
![ANGIOTENSIN II, HUMAN Structure](CAS/GIF/4474-91-3.gif)
- CAS No.
- 4474-91-3
- Chemical Name:
- ANGIOTENSIN II, HUMAN
- Synonyms
- ANGIOTENSIN II;Ang II;DRVYIHPF;TY-10721;AngiotensinⅡ;ANGIOTENSIN-2;H-DRVYIHPF-OH;angiotensin renin;ANTI-ANGIOTENSIN II;ile(5)-angiotensini
- CBNumber:
- CB0338057
- Molecular Formula:
- C50H71N13O12
- Molecular Weight:
- 1046.2
- MOL File:
- 4474-91-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/5 17:10:12
Boiling point | 809.08°C (rough estimate) |
---|---|
Density | 1.1257 (rough estimate) |
refractive index | 1.6700 (estimate) |
RTECS | BW2165000 |
storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
solubility | insoluble in DMSO; insoluble in EtOH; ≥100.2 mg/mL in H2O |
form | Powder |
pka | pK1: 10.37 (25°C) |
color | orange |
Water Solubility | Soluble in Water (25 mg/ml), and 5% Acetic Acid (1 mg/ml). |
Sequence | H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH |
Stability | Hygroscopic |
InChIKey | CZGUSIXMZVURDU-JZXHSEFVSA-N |
ANGIOTENSIN II, HUMAN price More Price(9)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A9525 | Angiotensin II human ≥93% (HPLC), powder | 4474-91-3 | 1MG | ₹3897 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9525 | Angiotensin II human ≥93% (HPLC), powder | 4474-91-3 | 5MG | ₹8129.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9525 | Angiotensin II human ≥93% (HPLC), powder | 4474-91-3 | 5X1MG | ₹14289 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9525 | Angiotensin II human ≥93% (HPLC), powder | 4474-91-3 | 10MG | ₹14960.15 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | A9525 | Angiotensin II human ≥93% (HPLC), powder | 4474-91-3 | 25MG | ₹26856.83 | 2022-06-14 | Buy |
ANGIOTENSIN II, HUMAN Chemical Properties,Uses,Production
Description
It is known that tumor tissues including metastatic lymph nodes are composed of newly growing vessels which lack blood flow autoregulation and are influenced only secondarily by the responding somatic vessels. Human angiotensin II (AT II). a vasopressor, was introduced in Japan to improve the efficacy of systemic chemotherapy. In patients with various advanced cancers, i.v. infusion of AT II to achieve a mean blood pressure of 1.5 times of baseline (but not over 150 mm Hg) followed by a bolus injection of conventional cytotoxic agents increases blood flow 5-7 fold in tumor tissues and therefore, increases drug delivery to the target tissue resulting in enhanced chemotherapeutic effects. This induced-hypertension chemotherapy regimen can be performed safely with minimal side effects.
Uses
Cardiopulmonary resuscitation - not yet an approved application
General Description
Functions in blood pressure maintenance. Stimulates the release of aldosterone from the adrenal gland. Has strong vasoconstrictive effects. Increases the entry of Ca2+ in heart muscle via voltage-sensitive channels and activates myosin light chain kinase. Activates JAK2 in smooth muscle cells. Activates p125FAK and a cytosolic 115-120 kDa calcium-dependent tyrosine kinase in rat epithelial cells. Also activates pp60c-src in vascular smooth muscle cells. Inhibits adenylate cyclase activity in spontaneously hypertensive rats.
ANGIOTENSIN II, HUMAN Preparation Products And Raw materials
Raw materials
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Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | China | 10978 | 58 | Inquiry |
Shanghai Aosiris new Material Technology Co., LTD | 86-15139564871 +8615139564871 | China | 264 | 58 | Inquiry |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | China | 973 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29900 | 58 | Inquiry |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | China | 10260 | 58 | Inquiry |
BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
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