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FMOC-LYS(BOC)(ME)-OH

FMOC-LYS(BOC)(ME)-OH Structure
CAS No.
951695-85-5
Chemical Name:
FMOC-LYS(BOC)(ME)-OH
Synonyms
Fmoc-Lys(Me,Boc);FMOC-LYS(ME,BOC)-OH;FMOC-LYS(BOC)(ME)-OH;FMOC-L-LYS(BOC, ME)-OH;Boc-L-Lys(Fmoc)(Me)-OH;FMOC-LYSINE(BOC)(ME)-OH;Fmoc-Lys(Me,Boc)-OH,95%;Fmoc-Lys(Me,Boc)-OH, >=97%;FMOC-LYS(BOC)(ME)-OH USP/EP/BP;Fmoc-Lys(Me,Boc)-OH Novabiochem
CBNumber:
CB3465262
Molecular Formula:
C27H34N2O6
Molecular Weight:
482.57
MOL File:
951695-85-5.mol
Modify Date:
2025/1/27 9:38:02

FMOC-LYS(BOC)(ME)-OH Properties

Melting point 85-87℃
Boiling point 665.4±55.0 °C(Predicted)
Density 1.200
storage temp. -20°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
pka 3.88±0.21(Predicted)
color White to off-white
InChIKey JHMSFOFHTAYQLS-QHCPKHFHSA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
WGK Germany  WGK 2 water endangering
HS Code  2924 29 70

FMOC-LYS(BOC)(ME)-OH price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 8.52106 Fmoc-Lys(Me,Boc)-OH Novabiochem? 951695-85-5 500MG ₹29810.01 2022-06-14 Buy
Sigma-Aldrich(India) 8.52106 Fmoc-Lys(Me,Boc)-OH Novabiochem? 951695-85-5 1G ₹59660 2022-06-14 Buy
Sigma-Aldrich(India) 8.52106 Fmoc-Lys(Me,Boc)-OH Novabiochem? 951695-85-5 8521060005 ₹365680 2022-06-14 Buy
Product number Packaging Price Buy
8.52106 500MG ₹29810.01 Buy
8.52106 1G ₹59660 Buy
8.52106 8521060005 ₹365680 Buy

FMOC-LYS(BOC)(ME)-OH Chemical Properties,Uses,Production

Description

Fmoc-lys (BOC) (ME)-OH is a kind of protected form of lysine. Lysine is double-protected by butyloxycarbonyl (BOC) and 9H-fluoren-9-ylmethoxycarbon (FMOC). It is a derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. The Boc protecting group can be removed through the TFA-mediated cleavage reaction. As a kind of protected amino acid, it is an important intermediate in various fields such as peptide synthesis, asymmetric synthesis, medicinal chemistry as well as polymer chemistry.

Uses

  1. Heterochromatin protein 1 (HP1) depends on trimethylation of H3 Lys 9; aggregation of chromatines depends on Lys methylation
  2. Fmoc-Lys(Boc, Me)-OH is useful for preparing monomethylated histone fragments utilized in studying the regulatory roles of methylated histones. Fmoc-Lys(Boc,Me)-OH can be coupled using standard activating procedures. The Boc group on the side epsilon nitrogen atom is removed with TFA, usually at the same time as the peptide is cleaved from the resin.
  3. Fmoc-Lys(Boc, Me)-OH is a novel derivative for the introduction of monomethyl-lysine during Fmoc SPPS. Coupling can be carried out using any standard activation method. Removal of the Boc protecting group occurs during the course of the TFA-mediated cleavage reaction.

General Description

Fmoc protected N-methylated lysine

References

http://www.chempep.com/ChemPep_Products2_Fmoc-Amino-Acid_Fmoc-Lys_Boc_Me_-OH.htm
https://en.wikipedia.org/wiki/Peptide_synthesis
Tung, C. L., et al. "A fluorogenic probe for recognizing 5-hydroxylysine inspired by serine/threonine ligation. " Chemical Communications 50.40(2014):5298-300.

FMOC-LYS(BOC)(ME)-OH Preparation Products And Raw materials

Global( 139)Suppliers
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JSK Chemicals +919879767970 Gujarat, India 3756 58 Inquiry
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
Adachibio Inc. +8108027837258 China 992 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-+86-371-66670886 China 19843 58 Inquiry
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BOC Sciences +1-631-485-4226 United States 19552 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22855 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 +8617705817739 China 52849 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19908 58 Inquiry

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FMOC-LYS(BOC)(ME)-OH Spectrum

N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-TERT-BUTYLOXYCARBONYL-N-EPSILON-METHYL-L-LYSINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-T-BUTYL-OXYCARBONYL-N-EPSILON-METHYL-L-LYSINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-T-BUTOXYCARBONYL-N-EPSILON-METHYL-L-LYSINE N-ALPHA-FMOC-N-EPSILON,EPSILON-T-BOC-METHYL-L-LYSINE N-ALPHA-FMOC-N-EPSILON-METHYL-N-EPSILON-T-BOC-L-LYSINE FMOC-LYS(BOC)(ME)-OH FMOC-LYSINE(BOC)(ME)-OH FMOC-L-LYS(BOC, ME)-OH N'-[(1,1-Dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N'-methyl-L-lysine (S)-1-(9H-fluoren-9-yl)-10,13,13-trimethyl-3,11-dioxo-2,12-dioxa-4,10-diazatetradecane-5-carboxylic acid FMoc-N-epsilon-Methyl-N-epsilon-t-Boc-L-lysine Fmoc-Lys(Me,Boc)-OH, >=97% Nalpha-Fmoc-Nepsilon-methyl-Nepsilon-Boc-L-lysine Fmoc-Lys(Me,Boc)-OH Novabiochem (9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(Boc, Me)-OH Fmoc-Lys(Me,Boc)-OH N-Fmoc-N'-Boc-N'-Methyl-Lysine N6-[(tert-Butoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-methyl-L-Lysine, 97% L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-methyl- (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoicaci FMOC-LYS(BOC)(ME)-OH USP/EP/BP Boc-L-Lys(Fmoc)(Me)-OH N'-tert-butyloxycarbonyl-N-fluorenylmethoxycarbonyl-N'-methyl-L-lysine (2S)-6-{[(tert-butoxy)carbonyl](methyl)amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]hexanoic acid FMOC-LYS(ME,BOC)-OH Fmoc-Lys(Me,Boc) N6-Boc-N2-Fmoc-N6-methyl-L-lysine N2-(((9H-fluorene-9-yl)methoxy)oxo)-N6-(tertbutyloxyoxo)-N6-methyl-L-lysine Fmoc-Lys(Me,Boc)-OH,95% 951695-85-5 amino acids