Nonathymulin
- CAS No.
- 63958-90-7
- Chemical Name:
- Nonathymulin
- Synonyms
- STF;Nonathymulin;SERUM THYMIC;THYMIC FACTOR;Zinc Thymulin;ThymulinAcetate;Thymalin/Thymulin;Thymulin(Thymalin);Thymic serum factor;THYMIC FACTOR SERUM
- CBNumber:
- CB3485859
- Molecular Formula:
- C33H54N12O15
- Molecular Weight:
- 858.85
- MOL File:
- 63958-90-7.mol
- Modify Date:
- 2024/7/11 17:04:31
| Boiling point | 1658.9±65.0 °C(Predicted) |
|---|---|
| Density | 1.417±0.06 g/cm3(Predicted) |
| storage temp. | −20°C |
| solubility | deionized water: soluble |
| pka | 3.08±0.10(Predicted) |
| form | Lyophilized powder |
| color | white |
| Sequence | Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn-OH |
| InChIKey | LIFNDDBLJFPEAN-BPSSIEEOSA-N |
| SMILES | C(O)(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)CNC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCC(=O)N1 |
Nonathymulin Chemical Properties,Uses,Production
Description
Nonathymulin, also known as Serum Thymic Factor, is a synthetic thymic peptide hormone. It is a thymus-dependent nonapeptide found in normal blood. Stimulates the formation of E rosettes and is believed to be involved in T-cell differentiation. It also acts as an effector on proinflammatory mediators/cytokines.
Uses
As a synthetic nonapeptide hormone, nonathymulin exhibits anti-apoptotic, anti-diabetic, anti-inflammatory, and immunomodulatory activities. In vivo, FTS increases activity of superoxide dismutase (SOD) and decreases activation of ERK, inhibiting cephaloridine-induced kidney damage and dysfunction.
Mechanism of action
The thymus produces a nonapeptide capable of inducing T cell surface markers and T cell functions in immature lymphoid cells. This peptide is found partly bound to a carrier protein in the circulation from where it has been isolated (hence its name of serum thymic factor (nonathymulin, FTS)). Immunofluorescence studies using an antibody raised against synthetic FTS has shown that it is produced by the thymic epithelium. Its mode of action at the cellular level involves the binding to specific high affinity receptors.
Nonathymulin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | China | 1090 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
| Sichuan Tai Hui Biotechnology Co., Ltd | +86-18224031330 +86-18081096520 | China | 24 | 58 | Inquiry |
| Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | China | 9311 | 58 | Inquiry |
| Shanghai Affida new material science and technology center | +undefined15081010295 | China | 114 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12458 | 58 | Inquiry |
| Shanghai Yunao International Trade Co., Ltd | +8617621705551 | China | 265 | 58 | Inquiry |
| qingdao future trading Co., Ltd | +86-13335044410 +86-13335044410 | China | 110 | 58 | Inquiry |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | China | 10978 | 58 | Inquiry |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | China | 616 | 58 | Inquiry |