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Semax

Semax Structure
CAS No.
80714-61-0
Chemical Name:
Semax
Synonyms
Met-Glu-His-Phe-Pro-Gly-Pro;Semax;MEHFPGP;lemod solu;SemaxAcetate;prednol [inj.];Peptides Semax;Semax/ACTH (4-10);ACTH (4-7), Pro-Gly-Pro-;Semax Acetate sermaglutide
CBNumber:
CB81313729
Molecular Formula:
C37H51N9O10S
Molecular Weight:
813.92
MOL File:
80714-61-0.mol
MSDS File:
SDS
Modify Date:
2024/7/1 15:29:05

Semax Properties

Boiling point 1335.2±65.0 °C(Predicted)
Density 1.391±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility H2O: >2mg/mL
pka 3.43±0.20(Predicted)
form powder
color white to tan
Water Solubility Soluble to 2 mg/ml in water
Sequence H-Met-Glu-His-Phe-Pro-Gly-Pro-OH
InChIKey AFEHBIGDWIGTEH-YNWVLKOQNA-N
SMILES N1(CCC[C@H]1C(=O)NCC(=O)N1CCC[C@H]1C(=O)O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CCSC)CC1N=CNC=1)CC1=CC=CC=C1 |&1:4,15,21,25,29,38,r|

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
WGK Germany  3
NFPA 704
0
2 0

Semax price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S8826 Semax ≥98% (HPLC) 80714-61-0 1MG ₹16237.5 2022-06-14 Buy
Product number Packaging Price Buy
S8826 1MG ₹16237.5 Buy

Semax Chemical Properties,Uses,Production

Description

Semax is a synthetic analogue of the adrenocorticotropic hormone, a hormone responsible for the production of cortisol which in turn regulates glucose and lipid metabolism and helps to maintain blood pressure. In the hippocampus, Semax rapidly elevates the levels of brain-derived neurotrophic factor (BDNF), a protein important in encouraging growth and differentiation of new neurons and synapses. BDNF is active in the hippocampus, cortex, and forebrain and is important for memory, coordination, concentration, and learning. Semax also works to activate the dopaminergic and serotonergic systems to help prime the brain for action and to induce a controlled state of mental stress.

benefits

Over continued use, guests have seen benefits such as:Reduces anxiety and depression;Improves mental clarity, memory, and focus

Biological Functions

Semax altered the expression of genes that modulate the amount and mobility of immune cells. It also could enhanced the expression of genes that encode chemokines and immunoglobulins. It can increase attention and short-term memory, improve Non-proliferative Diabetic Neuropathy, and can help during recovery from Stroke/Hypoxia

Uses

Semax has been prescribed for anxiety, memory improvement, ischemic events, stroke, nerve regeneration, ADHD, opioid withdrawal and even chronic diseases such as ALS, Parkinson’s Disease, and Alzheimer’s. Semax has been known to be used as an Adderall alternative.

Mechanism of action

Though the exact mechanism of action of Semax is unclear, there is evidence that it may act through melanocortin receptors. Semax is a neuroprotective peptide, which aims to slow disease progression and secondary injuries by halting/slowing the loss of neurons and is neurorestorative.

Clinical Use

Semax has undergone extensive study in Russia and is on the Russian List of Vital & Essential Drugs approved by the Russian Federation government on December 7, 2011. Medical uses for Semax include treatment of stroke, transient ischemic attack, memory and cognitive disorders, peptic ulcers, optic nerve disease, and to boost the immune system.

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ACTH (4-7), Pro-Gly-Pro- ACTH (4-7), Pro-Gly-Pro trifluoroacetate salt L-Methionyl-L-a-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl-L-proline trifluoroacetate salt Semax (PRO8,GLY9,PRO10)ACTH-(4-10) SemaxAcetate L-METHIONYL-L-Α-GLUTAMYL-L-HISTIDYL-L-PHENYLALANYL-L-PROLYLGLYCYL-L-PROLINE Peptides Semax L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl- succinic acid, 21-monoester with 11beta,17,21-trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione, monosodium s... prednol [inj.] lemod solu ACTH (4-7), Pro-Gly-Pro- ISO 9001:2015 REACH L-Methionyl-L-α-glutamylhistidyl-L-phenylalanyl-L-prolylglycyl-L- proline Met-Glu-His-Phe-Pro-Gly-Pro L-Proline, L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-prolylglycyl- Semax/ACTH (4-10) Semax Acetate sermaglutide MEHFPGP 80714-61-0 C37H51N9O10S 80714-61-0