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(D-Ala2)-Leu-Enkephalin

CAS No.: 64963-01-5

Chemical Name:: (D-Ala2)-Leu-Enkephalin

Synonyms: (D-ALA2)-LEU-ENKEPHALIN;TYR-D-ALA-GLY-PHE-LEU;D-ALA2-LEU5-ENKEPHALIN;(D-Ala)-Leu-Enkephalin;Tyr-D-Ala-Gly-Phe-Leu-OH;Pentapeptide-3/Leuphasyl;H-TYR-D-ALA-GLY-PHE-LEU-OH;Leuphasyl / Pentapeptide-3;[D-ALA2]-LEUCINE ENKEPHALIN;Leuphasyl / Pentapeptide-18

CBNumber:: CB3667734

Molecular Formula:: C29H39N5O7

Molecular Weight:: 569.65

MOL File:: 64963-01-5.mol

Modify Date:: 2024/7/10 17:45:06

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(D-Ala2)-Leu-Enkephalin Properties

Melting point	160-163.5 °C
Boiling point	991.9±65.0 °C(Predicted)
Density	1.257±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	DMF (Slightly), DMSO (Slightly)
form	Solid
pka	3.40±0.10(Predicted)
color	White to Off-White
InChIKey	ZHUJMSMQIPIPTF-JMBSJVKXSA-N
SMILES	C(O)(=O)[C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1=CC=C(O)C=C1)N

SAFETY

Risk and Safety Statements

WGK Germany	3

(D-Ala2)-Leu-Enkephalin price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	E5008	[D-Ala2]-Leucine enkephalin ≥97% (HPLC)	64963-01-5	5MG	₹5390.85	2022-06-14	Buy

Product number	Packaging	Price	Buy
E5008	5MG	₹5390.85	Buy

(D-Ala2)-Leu-Enkephalin Chemical Properties,Uses,Production

Definition

The leucine-enkephalin (Tyr-Gly-Gly-Phe-Leu, Leu-enk) is a natural endogenous ligand for opiate receptors. Leu-enk is rapidly metabolized in vivo and in vitro[1]. (D-Ala2)-Leu-Enkephalin, a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin.

benefits

(D-Ala2)-Leu-Enkephalin is widely distributed in the human body and has essential physiological functions. It has a unique effect on brain cells and can activate sleeping brain cells and have a good recovery effect on the sequelae caused by brain damage. It plays an important role in immune function, including increasing the activity of the immune system, T lymphocytes, NK cells, macrophages, antiviral, and the release of gamma interferon. It can participate in immune regulation by promoting the secretion of endocrine cells by activated immune cells, thereby affecting DNA's gene regulation and expression functions.

References

[1] H. Hasegawa, S. Baba, Y. Shinohara. “Synthesis of [D-Ala2]Leu-enkephalin and [D-Ala2, D-Leu5]Leu-enkephalin with high specific tritiated activity in the leucine residue.” Journal of The Chemical Society-perkin Transactions 1 12 1 (1990): 2641–2644.

(D-Ala2)-Leu-Enkephalin Preparation Products And Raw materials

Raw materials

Preparation Products

(D-Ala2)-Leu-Enkephalin Suppliers

Global( 207)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Cellmano Biotech Limited	0551-65326643 18156095617	China	999	58	Inquiry
Shanghai Yunao International Trade Co., Ltd	+8617621705551	China	265	58	Inquiry
Wuhan Cell Pharmaceutical Co., Ltd	+86-13129979210 +86-13129979210	China	376	58	Inquiry
Wuhan Haorong Biotechnology Co.,ltd	+86-18565342920; +8618565342920	China	292	58	Inquiry
Nantong Guangyuan Chemicl Co,Ltd	+undefined17712220823	China	616	58	Inquiry
Shanghai Affida new material science and technology center	+undefined15081010295	China	114	58	Inquiry
hebei hongtan Biotechnology Co., Ltd	+86-86-1913198-3935 +8617331935328	China	973	58	Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd	+8618740459177	China	1142	58	Inquiry
Shanghai Getian Industrial Co., LTD	+86-15373193816 +86-15373193816	China	274	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
Cellmano Biotech Limited	58
Shanghai Yunao International Trade Co., Ltd	58
Wuhan Cell Pharmaceutical Co., Ltd	58
Wuhan Haorong Biotechnology Co.,ltd	58
Nantong Guangyuan Chemicl Co,Ltd	58
Shanghai Affida new material science and technology center	58
hebei hongtan Biotechnology Co., Ltd	58
Shaanxi TNJONE Pharmaceutical Co., Ltd	58
Shanghai Getian Industrial Co., LTD	58

64963-01-5((D-Ala2)-Leu-Enkephalin)Related Search:

PALMITOYL TETRAPEPTIDE-3 Palmitoyl Pentapeptide Palmitoyl Tripeptide-5 Acetyl Tetrapeptide-5 NONAPEPTIDE-1

Acetyl Octapeptide-3 PALMITOYL TRIPEPTIDE-1 Lipopeptide Acetate Palmitoyl Pentapeptide-3 Matrixyl，PALMITOYL PENTAPEPTIDE-3

TYR-D-ALA-GLY-PHE-MET ACOH H2O Hexapeptide 9 HEXAPEPTIDE-3 Aprotinin Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide

Pentapeptide-25 TYR-D-ALA-GLY-PHE-LEU H-TYR-D-ALA-GLY-PHE-LEU-ARG-ARG-ILE-ARG-OH

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H-TYR-D-ALA-GLY-PHE-LEU-OH D-ALA2-LEU5-ENKEPHALIN [D-ALA2]-LEUCINE ENKEPHALIN TYR-D-ALA-GLY-PHE-LEU N-[N-[N-(N-L-tyrosyl-D-alanyl)glycyl]-L-phenylalanyl]-L-leucine (D-alanine2)leucine enkephalin L-Tyr-D-Ala-Gly-L-Phe-L-Leu-OH Tyr-D-Ala-Gly-Phe-Leu-OH 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoic acid 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenyl-propanoyl]amino]-4-methyl-valeric acid 2-[[2-[2-[2-[[2-azanyl-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]ethanoylamino]-3-phenyl-propanoyl]amino]-4-methyl-pentanoic acid [D-Ala2]-Leucine enkephalin,Tyr-D-Ala-Gly-Phe-Leu Pentapeptide-3/Leuphasyl L-Tyrosyl-D-alanylglycyl-L-phenylalanyl-L-leucine Tyrosyl-D-alanylglycylphenylalanylleucine Leuphasyl / Pentapeptide-3 Lab Supply High Purity Pentapeptide-18 Powder CAS 64963-01-5 with Best Price TYR-D-ALA-GLY-PHE-LEU USP/EP/BP 2-[[2-[[2-[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoylamino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoicaci L-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl- Pentapeptide-18/Leuphasyl with reduce facial muscle Leuphasyl / Pentapeptide-18 [D-Ala2]leucine-enkephalin,Tyr-D-Ala-Gly-Phe-Leu, >99% [D-ALA2]LEUCINE-ENKEPHALIN, >99% (D-Ala)-Leu-Enkephalin (D-Ala2)-Leu-Enkephalin H-Tyr-D-Ala-Gly-Phe-Leu-OH (D-ALA2)-LEU-ENKEPHALIN 64963-01-5 C29H39N5O7 Enkephalins Opioid Peptides Peptides Biochemicals and Reagents Amino Acids and Peptides BioChemical