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Aprotinin

Aprotinin Structure
CAS No.
9087-70-1
Chemical Name:
Aprotinin
Synonyms
BPTI;Bovine pancreatic trypsin inhibitor;fosten;rp-9921;TRASYLOL;onquinin;repulson;riker52g;trazinin;zymofren
CBNumber:
CB3329436
Molecular Formula:
C284H432N84O78R2S7
Molecular Weight:
6495.43988
MOL File:
9087-70-1.mol
MSDS File:
SDS
Modify Date:
2024/4/9 22:15:29
Request For Quotation

Aprotinin Properties

Melting point >234oC (dec.)
storage temp. 2-8°C
solubility glycerol: soluble3mg/mL, clear, colorless (equilibration buffer containing 5% glycerol)
form lyophilized powder
color white
Water Solubility Freely soluble in water and in aqueous buffers of low ionic strength.
Merck 13,761
Sequence H-Pro-Asp-Phe-Cys-Leu-Glu-Pro-Pro-Tyr-Thr-Gly-Pro-Cys-Lys-Ala-Arg-Ile-Ile-Arg-Tyr-Phe-Tyr-Asn-Ala-Lys-Ala-Gly-Leu-Cys-Gln-Thr-Phe-Val-Tyr-Gly-Gly-Cys-Arg-Ala-Lys-Arg-Asn-Asn-Phe-Lys-Ser-Ala-Glu-Asp-Cys-Met-Arg-Thr-Cys-Gly-Gly-Ala-OH
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey RWLBZZCCAZDWSE-BNRYNCRGNA-N

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xn,Xi
Risk Statements  42/43-36/37/38-20/21/22
Safety Statements  22-45-36/37-36-26
WGK Germany  1
RTECS  YN5080000
F  10-21
HS Code  35040000
Toxicity LD50 i.v. in mice: 2500000 kallikrein inhibitor units/kg (Trautschold)

Aprotinin price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SRE0078 Aprotinin from bovine lung lyophilized powder, ≥3?TIU/mg solid, Suitable for manufacturing of diagnostic kits and reagents 9087-70-1 10MG ₹14797.78 2022-06-14 Buy
Sigma-Aldrich(India) SRE0078 Aprotinin from bovine lung lyophilized powder, ≥3?TIU/mg solid, Suitable for manufacturing of diagnostic kits and reagents 9087-70-1 100MG ₹88039.73 2022-06-14 Buy
Sigma-Aldrich(India) SRE0050 Aprotinin from bovine lung saline solution, 3-7?TIU/mg protein, Suitable for manufacturing of diagnostic kits and reagents 9087-70-1 5ML ₹21931.45 2022-06-14 Buy
Sigma-Aldrich(India) SRE0078 Aprotinin from bovine lung lyophilized powder, ≥3?TIU/mg solid, Suitable for manufacturing of diagnostic kits and reagents 9087-70-1 250MG ₹232423.58 2022-06-14 Buy
Sigma-Aldrich(India) SRE0050 Aprotinin from bovine lung saline solution, 3-7?TIU/mg protein, Suitable for manufacturing of diagnostic kits and reagents 9087-70-1 10ML ₹31966.23 2022-06-14 Buy
Product number Packaging Price Buy
SRE0078 10MG ₹14797.78 Buy
SRE0078 100MG ₹88039.73 Buy
SRE0050 5ML ₹21931.45 Buy
SRE0078 250MG ₹232423.58 Buy
SRE0050 10ML ₹31966.23 Buy

Aprotinin Chemical Properties,Uses,Production

Description

Aprotinin is a reversible inhibitor of serine proteases such as trypsin (Ki = 0.06 pM), chymotrypsin (Ki = 9.5 nM), and kallikrein (Ki = 0.8 nM). It is a much weaker inhibitor of thrombin (Ki = 0.1-0.8 mM) and trypsinogen (Ki = 2 μM). Aprotinin also competitively inhibits nNOS and iNOS with Ki values of 50 and 78 μM, respectively. Aprotinin is widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest.

Chemical Properties

white powder

Uses

Aprotinin is largely used as an inhibitor of trypsin.

General Description

Trypsin inhibitor, pancreas type from bovine lung. It is known as Pancreatic trypsin inhibitor (BPTI). Aprotinin, also known as pancreatic trypsin inhibitor and trypsin-kallikrein inhibitor, is found to be expressed in lungs, spleen, liver, and pancreas. It is also found to be present in the free form in calf serum.

Safety Profile

Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and SOx.

Aprotinin Preparation Products And Raw materials

Raw materials

Trichloroacetic acid Ammonia Acetic acid Acetone

Preparation Products

Aprotinin Suppliers

Global( 376)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Central Drug House(P) Ltd. 91-11-49404040 New Delhi, India 6160 58 Inquiry
Arun & Co. 91-22-67723000 Maharashtra, India 15 58 Inquiry
Anand Agencies 91-20-24454597 Maharashtra, India 2337 58 Inquiry
Shah TC Overseas Pvt. Ltd. 91-11-27902000 Delhi, India 35 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
Hangzhou Meiya Pharmaceutical Co Ltd +86-021-33686691 +8618001850931 China 58 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Sisco Research Laboratories Pvt. Ltd. 58
Triveni chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Central Drug House(P) Ltd. 58
Arun & Co. 58
Anand Agencies 58
Shah TC Overseas Pvt. Ltd. 58
Pharma Affiliates 58
Hangzhou Meiya Pharmaceutical Co Ltd 58

Aprotinin Spectrum

Aprotinin(9087-70-1)MS

9087-70-1(Aprotinin)Related Search:

Proteinase K ENTEROKINASE Trypsin Chymotrypsin Pepstatin
TYR-D-ALA-GLY-PHE-LEU Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide Pentapeptide-25 TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Aluminum acetylacetonate
TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) COBALT(II) ACETYLACETONATE Benzyl isocyanide Ferric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III)
TERT-BUTYL ISOCYANIDE Cupric acetylacetonate KUNITZ SOYBEAN TRYPSIN INHIBITOR,IMMOBILIZED SOYBEAN TRYPSIN INHIBITOR,SOYBEAN TRYPSIN INHIBITOR
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TRYPSIN INHIBITOR, PANCREAS TYPE TRYPSIN INHIBITOR (BASIC) TRYPSIN INHIBITOR, BOVINE LUNG TRASYLOL antikrein antilysin antilysine aprotininfrombovinelung basicpancreatictrypsininhibitor RecoMbinant aprotinin APROTININ-AGAROSE APROTININ, BOVINE APROTININ, BOVINE AGAROSE CONJUGATE APROTININ BOVINE LUNG Aprotinin froM bovine lung, ca. 140 U/Mg lyophil. Monoclonal Anti-Acetylated Lysine antibody produced in mouse Anti-Acetylated Lysine: Biotin Anti-Acetylated Lysine-Biotin antibody produced in rabbit Anti-Acetylated Lysine antibody produced in rabbit Aprotinin from bovine lung, >=5400 KIU/mg EZNA KIT ENDO-FREE PLASMID GIGA H-ARG-PRO-ASP-PHE-CYS-LEU-GLU-PRO-PRO-TYR-THR-GLY-PRO-CYS-LYS-ALA-ARG-ILE-ILE-ARG-TYR-PHE-TYR-ASN-ALA-LYS-ALA-GLY-LEU-CYS-GLN-THR-PHE-VAL-TYR-GLY-GLY-CYS-ARG-ALA-LYS-ARG-ASN-ASN-PHE-LYS-SER-ALA-GLU-ASP-CYS-MET-ARG-THR-CYS-GLY-GLY-ALA-OH EC: 3.4.21.9 APROTININ bayera-128 fosten kallikrein-trypsininactivator kirrichter onquinin pancreaticbasictrypsininhibitor pancreatictrypsininhibitor pancreatictrypsininhibitor(kunitz) repulson riker52g rp-9921 trazinin trypsininhibitor,pancreaticbasic trypsin-kallikreininhibitor(kunitz) zymofren Aprotinin solution Anti-Acetylated Lysine:HRP Anti-Acetylated Lysine-Peroxidase antibody produced in rabbit APROTININ FROM BOVINE LUNGAFFINITY PURIF IED APROTININ FROM BOVINE LUNG CELL CULTURE TESTED APROTININ FROM BOVINE LUNG, ~8000 U/MG P ROTEIN APROTININ, BOVINE LUNG FOR GELFILTRATION CHROMATOG APROTININ-AGAROSE FROM BOVINE LUNG APROTININ, BOVINE, RECOMBINANT APROTININ FROM BOVINE LUNG, LYOPH.,~7000 U/MG* Aprotinin from bovine lung, ca. 140 U/mg Antilysi. Trypsin Inhibitor, pankreatisch basisch Kunitz protease inhibitor Aids043659 Aids-043659 Rpdfcleppytgpckariiryfynakaglcqtfvyggcrakrnnfksaedcmrtcgga Kunity Trypsin Inhibitor of Aprotinium Aprotinin from bovine lung,Trypsin inhibitor (basic)