Palmitoyl Tripeptide-5
- CAS No.
- 623172-56-5
- Chemical Name:
- Palmitoyl Tripeptide-5
- Synonyms
- SYN-COLL;Pal-KVK;Pal-Lys-Val-Lys-OH;PalMtioyl Tripeptide-5;Palmitoyl Tripepitde-5;Palmitoyl Tripeptide-5(Pal-KVK);PT5P;Palm-KVK;3,SYN-COLL;UNII-4IV5XO4TGK
- CBNumber:
- CB42490021
- Molecular Formula:
- C35H66F3N5O7
- Molecular Weight:
- 725.94
- MOL File:
- 623172-56-5.mol
- Modify Date:
- 2024/7/2 17:33:06
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
|---|---|
| solubility | DMF: 30mg/mL; DMSO: 30mg/mL; Ethanol: 30mg/mL; Ethanol:PBS (pH 7.2) (1:3): 0.25mg/mL |
| form | A crystalline solid |
| Sequence | Pal-Lys-Val-Lys |
| InChIKey | BSPABZINJHASIV-PRQXCCHZNA-N |
| SMILES | C(F)(F)(F)C(=O)O.[C@@H](CCCCN)(NC(=O)CCCCCCCCCCCCCCC)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(=O)O)CCCCN |&1:7,34,41,r| |
Palmitoyl Tripeptide-5 Chemical Properties,Uses,Production
Description
Palmitoyl tripeptide-5 is a synthetic peptide and consists of 3 chains of amino acids link together with fatty acids. Palmitoyl tripeptide can enter epidermis and can penetrate deep into the dermis, where it can help to stimulate collagen production and helps to grow healthy tissue growth.
Uses
Palmitoyl Tripeptide-5 is made up of chains of amino acids and can penetrate the epidermis and enter deep into the dermis, where may help to stimulate collagen production and healthy tissue growth.
Application
Palmitoyl Tripeptide-5 is a component of cell transduction, and promotes the production of collagen. It is commonly used in anti-aging and anti-wrinkle cosmetics.
Definition
Palmitoyl tripeptide-5 is a Thrombospondin I (TSP-1) fragment presenting the sequence N-(1-oxohexadecyl)-L-lysyl-L-valyl-L-lysine. Palmitoyl tripeptide-5 was used in a cosmetic ingredient mix from a raw material supplier, containing spent grain wax and conjugated linoleic acid (CLA), to reduce skin redness in type I rosacea. This peptide has been used in patented cosmetic formulations for sensitive skin. Palmitoyl tripeptide-5 is used in anti-aging cosmetic products due to its ability to reduce MMP'S, promote the synthesis of type I and type II collagen from extracellular matrix, and inhibit melanin production by reducing tyrosinase activity[1].
Mechanism of action
Palmitoyl tripeptide-5 acts on the specific skin receptors and stimulates the production of collagen in our skin cells. It firms our skin, reduces the appearance of wrinkles and fine-lines. It makes your skin look healthier and fresh.Palmitoyl Tripeptide-5 also interact with hyaluronic acid and elastin production system. The combine effect is increased water content, reduce wrinkling of skin and enhance the firmness of skin.
Safety
Palmitoyl Tripeptide-5 is a new ingredient and there are few researchers on it. But according to skincare specialist, Palmitoyl Tripeptide-5 is safe to use on any skin. It can’t react to your skin. There are no reported issue of any toxicity, allergy, sensitivity and hormone disruption. If you have a sensitive skin, you may react to anti-aging creams. You common skin reactions are redness, itching, stinging at the site of application.
References
[1] Resende, Diana I. S. P, et al. "Usage of Synthetic Peptides in Cosmetics for Sensitive Skin." Pharmaceuticals (Basel) (2021).
Palmitoyl Tripeptide-5 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Shaanxi LonierHerb Bio Technology Co Ltd | +86-86-+86-86-029-87551862 +8617702909819 | China | 2605 | 58 | Inquiry |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | China | 999 | 58 | Inquiry |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49999 | 58 | Inquiry |
| Hebei Anlijie Biotechnology Co., Ltd | +8619031013551 | China | 145 | 58 | Inquiry |
| Apeloa production Co.,Limited | +8619933239880 | China | 853 | 58 | Inquiry |
| Shandong Hanjiang Chemical Co., Ltd | +86-0533-2066820 +8618369939125 | China | 974 | 58 | Inquiry |
| Shanghai Likang New Materials Co., Limited | +86-16631818819 +86-17736933208 | China | 9311 | 58 | Inquiry |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | China | 6938 | 58 | Inquiry |
| Shanghai Yunao International Trade Co., Ltd | +8617621705551 | China | 265 | 58 | Inquiry |