ChemicalBook > Product Catalog >API >Antibiotics >Peptides drug >Palmitoyl tetrapeptide-7

Palmitoyl tetrapeptide-7

Palmitoyl tetrapeptide-7 Structure
CAS No.
221227-05-0
Chemical Name:
Palmitoyl tetrapeptide-7
Synonyms
Pal-Gly-Gln-Pro-Arg-OH;Pal-Tetrapeptide-7;Palm-GQPR;Pal-GQPR-OH;Palmitoyl-GQPR;N-Palmitoylrigin;Pal-tetrapeptide-3;Pal-tetrapeptide-3/7;Palm-Gly-Gln-Pro-Arg;Palmitic four peptide -7
CBNumber:
CB01481648
Molecular Formula:
C34H62N8O7
Molecular Weight:
694.91
MOL File:
221227-05-0.mol
Modify Date:
2025/6/24 21:05:35

Palmitoyl tetrapeptide-7 Properties

Density 1.26±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 3.60±0.21(Predicted)
form Solid
color White to off-white
Sequence pal-Gly-Gln-Pro-Arg-OH
InChIKey IHRKJQSLKLYWBQ-QKDODKLFSA-N
SMILES C(O)(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)CCCCCCCCCCCCCCC

Palmitoyl tetrapeptide-7 Chemical Properties,Uses,Production

Description

Palmitoyl tetrapeptide-7, part of Matrixyl 3000, is a skin repair ingredient with anti-aging properties. It has anti-aging and stabilizing effects and is often used in cosmetics. It is a synthetic peptide composed of four amino acids (glycine-glutamine-proline-arginine) and palmitic acid. The addition of the fatty acid palmitic acid enhances the stability and permeability of the ingredient to the skin.

benefits

Palmitoyl tetrapeptide-7 is known to trigger the regeneration of collagen fibres in the skin, so it induces the natural production of collagen in the skin. After regular application, skin appearance can be changed considerably. It also restores moisture and also reduces roughness, fine lines, and wrinkles formed on the skin. It can penetrate deep layers of the skin and reduce the production of interleukins (IL). Interleukins are markers of any inflammation within the body. They are produced as a response to damage caused by external factors, like pollutants, free radicals, or other chemicals to the skin. Palmitoyl tetrapeptide-7 heals the skin and reduces the effect of inflammation. It conditions and rejuvenates the skin and makes it healthier.

Mechanism of action

Palmitoyl tetrapeptide-7 reduces the production of interleukin-6 (IL-6) by keratinocytes and fibroblasts, key cells in the skin. Interleukin-6 is a mediator of inflammation that causes faster degradation of extracellular matrix components, promotes wrinkle formation and reduces skin firmness and elasticity. Reduces IL-6 and other pro-inflammatory agents palmitoyl tetrapeptide-7, protecting extracellular matrix components from degradation, thus making the skin look younger.

Side effects

Palmitoyl tetrapeptide-7 is used in beauty products and cosmetics to suppress the production of excess interleukins, the chemical messengers that trigger the body's acute inflammatory response. This can lead to glycation damage, or the process by which glucose links with proteins and causes them to bind together, stiffening tissues. This negatively affects the skin's support system, comprised of collagen, elastin, and other proteins, and leads to wrinkles, sagging, and uneven skin tone.

References

[1] M. Ferreira. “Trending Anti-Aging Peptides.” Cosmetics (2020).

Palmitoyl tetrapeptide-7 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 291)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
GIHI CHEMICALS CO.,LIMITED +8618058761490 China 49983 58 Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd +86-17396673057 China 1143 58 Inquiry
Hebei Fengjia New Material Co., Ltd +86-0311-87836622 +86-18712993135 China 8051 58 Inquiry
Shandong Huizhihan Supply Chain Co., Ltd +86-13363081709 +86-13363000288 China 300 58 Inquiry
Changsha MOL Changes Biotechnology Co., Ltd. +8619375158599 China 5221 58 Inquiry
American HealthyMorph LLC +85269498027 China 169 58 Inquiry
BJV BIOTECH LTD +86-0755-23089946 +8619006605307 China 67 58 Inquiry
Changzhou Xuanming Pharmaceutical Technology Co., Ltd. +86-519-85525359 +86-15995072465 China 893 58 Inquiry
Shanghai UCHEM Inc. +862156762820 +86-13564624040 China 8151 58 Inquiry

Related articles

Matrixyl 3000/Palmitoyl Tetrapeptide-3 N-Palmitoylrigin Pal-tetrapeptide-3(7)+ Dipeptide-2 Palmitoyl Tetrapeptide-7(Pal-GQPR) N-(1-Oxohexadecyl)glycyl-L-glutaminyl-L-prolyl-L-arginine Palmitoyl Tetrapeptide-7, Matrixyl 3000 Palmitoyl Tetrapeptide-7/Palmitoyl Tetrapeptide-3 Palmitoyl Tetrapeptide-7/Matrixyl 3000/Palmitoyl Tetrapeptide-3 Palm-GQPR Palmitoyl-GQPR (S)-2-[(S)-1-[(S)-5-Amino-5-oxo-2-(2-palmitamidoacetamido)pentanoyl]pyrrolidine-2-carboxamido]-5-[(diaminomethylene)amino]pentanoic Acid L-Arginine, N-(1-oxohexadecyl)glycyl-L-glutaminyl-L-prolyl- Palmitoyl Tetrapeptide-3/7 Pal-tetrapeptide-3/7 Palmitic four peptide -7 Pal-tetrapeptide-3 Palmitoyl Tetrapeptide-7 Powder Pal-GQPR (Palmitoyl-TetraPeptide-7) Pal-Tetrapeptide-7 /Pal-Tetrapeptide-3 PALMITOYL TETRAPEPTIDE 3 USP/EP/BP Cosmetic Peptide Pharmaceutical Grade CAS?221227-05-0?99% Purity Palmitoyl Tetrapeptide-7/Palmitoyl Tetrapeptide-3 Powder (2S)-2-[[(2S)-1-[(2S)-5-amino-2-[[2-(hexadecanoylamino)acetyl]amino]-5-oxopentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid Pal-GQPR-OH Palm-Gly-Gln-Pro-Arg Pal-Gly-Gln-Pro-Arg-OH Pal-Tetrapeptide-7 Palmitoyl Tetrapeptide-7 inhibit,Inhibitor,Palmitoyl Tetrapeptide-3,Palmitoyl Tetrapeptide3,Palmitoyl Tetrapeptide 3 Palmotoyl Tetrapeptide-3/7 Palmitoyl Tetrapeptide-3/Palmitoyl Tetrapeptide-7 (Reference:Rigin) Pal-Gly-Gln-Pro-Arg-OH TFA Palmitoyl tetrapeptide 7 trifluoroacetate Palmitoyl Tetrapeptide-7、Palmitoyl-Rigin Oil Palmitoyl Tetrapeptide-7 221227-05-0 C34H62N8O7 BEAUTY PEPTIDES APIs 221227-05-0