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Superoxide dismutase

Superoxide dismutase Structure
CAS No.
9054-89-1
Chemical Name:
Superoxide dismutase
Synonyms
SOD;ORGOTEIN;SOD1;EC: 1.15.1.1;SOD-3;hrSOD;EC-SOD;Cuprein;rh-SOD1;Ontosein
CBNumber:
CB6401661
Molecular Formula:
NULL
Molecular Weight:
0
MOL File:
Mol file
MSDS File:
SDS
Modify Date:
2024/7/24 17:31:20

Superoxide dismutase Properties

storage temp. -20°C
solubility Dissolves readily at 5 mg/mL in 0.05 M potassium phosphate buffer, pH 7.8, containing 0.1 mM EDTA.
form powder
color blue-gray

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280-P271
Hazard Codes  B
Risk Statements  36/37/38
Safety Statements  26-36-24/25-22-23
WGK Germany  3
10-21
HS Code  35079090

Superoxide dismutase price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S9697 Superoxide Dismutase bovine recombinant, expressed in E. coli, lyophilized powder, ≥2500?units/mg protein, ≥90% (SDS-PAGE) 9054-89-1 15000UNITS ₹9312.9 2022-06-14 Buy
Sigma-Aldrich(India) S9697 Superoxide Dismutase bovine recombinant, expressed in E. coli, lyophilized powder, ≥2500?units/mg protein, ≥90% (SDS-PAGE) 9054-89-1 30000UNITS ₹12698.4 2022-06-14 Buy
Sigma-Aldrich(India) S9697 Superoxide Dismutase bovine recombinant, expressed in E. coli, lyophilized powder, ≥2500?units/mg protein, ≥90% (SDS-PAGE) 9054-89-1 75000UNITS ₹25918.5 2022-06-14 Buy
Sigma-Aldrich(India) SAB1303104 ANTI-SOD3 (N-TERM) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution 9054-89-1 400μL ₹47796.6 2022-06-14 Buy
Sigma-Aldrich(India) S9697 Superoxide Dismutase bovine recombinant, expressed in E. coli, lyophilized powder, ≥2500?units/mg protein, ≥90% (SDS-PAGE) 9054-89-1 300000UNITS ₹100954.5 2022-06-14 Buy
Product number Packaging Price Buy
S9697 15000UNITS ₹9312.9 Buy
S9697 30000UNITS ₹12698.4 Buy
S9697 75000UNITS ₹25918.5 Buy
SAB1303104 400μL ₹47796.6 Buy
S9697 300000UNITS ₹100954.5 Buy

Superoxide dismutase Chemical Properties,Uses,Production

Definition

Any of a type of antioxidant metalloenzymes that occur in aerobic and facultatitive bacteria and in eukarotes. They catalyze a reaction in which two molecules of the highly toxic, highly reactive, superoxide anion is converted into one molecule each of hydrogen peroxide and molecular oxygen.

benefits

Based on the metal cofactors present in the active sites, Superoxide dismutases (SODs) can be classified into four distinct groups: Copper-Zinc-SOD (Cu, Zn-SOD), Iron SOD (Fe-SOD), Manganese SOD (Mn-SOD), and Nickel SOD. The enzyme can serve as an anti-inflammatory agent and can also prevent precancerous cell changes. SOD is used in cosmetics and personal care products as an anti-aging ingredient and antioxidant due to its ability to reduce free radical damage to the skin, therefore preventing wrinkles, fine lines, and age spots, and it also helps with wound healing, softens scar tissue, protects against UV rays, and reduces other signs of aging. It has been reported that SOD has an important link in several human health problems including RBC-related disorders, cystic fibrosis (CF), postcholecystectomy pain syndrome, malignant breast disease, steroid-sensitive nephrotic syndrome, amyotrophic lateral sclerosis, neuronal apoptosis, AIDS, and cancer. In many animal models having myocardial ischemia-reperfusion injury, inflammation, cerebral ischemia-reperfusion injury, etc., SOD enzymes are found to be very effective. Furthermore, a strong association between the activity of SOD and Alzheimer's disease has been suggested by some researchers[1-2].

General Description

Superoxide dismutases are a group of low molecular weight metalloproteins present in all aerobic cells of plants, animals and micro-organisms. They provide protection against damaging reactions with the superoxide radical anion (O2-) by catalyzing its disproportionation into oxygen and hydrogen peroxide.

General Description

Superoxide dismutase (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications.

References

[1] Younus H. "Therapeutic potentials of superoxide dismutase" Int J Health Sci (Qassim)12(2018).
[2] Batinic-Haberle, Ines, et al. "Rational Design of Superoxide Dismutase (SOD) Mimics: The Evaluation of the Therapeutic Potential of New Cationic Mn Porphyrins with Linear and Cyclic Substituents." Inorganic Chemistry: A Research Journal that Includes Bioinorganic, Catalytic, Organometallic, Solid-State, and Synthetic Chemistry and Reaction Dynamics(2014).

Superoxide dismutase Preparation Products And Raw materials

Global( 360)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Sinoway Industrial co., ltd. 0592-5800732; +8613806035118 China 990 58 Inquiry
Shijiazhuang Dingmin Pharmaceutical Sciences Co., Ltd. +86-0311-67591193 +8613931880626 China 238 58 Inquiry
Hebei Guanlang Biotechnology Co,.LTD +86-19930503253; +8619930503252 China 5835 58 Inquiry
Hebei Kingfiner Technology Development Co.Ltd +86-15532196582 +86-15373005021 China 2989 58 Inquiry
Shaanxi Haibo Biotechnology Co., Ltd +undefined18602966907 China 1000 58 Inquiry
Wuhan Quanjinci New Material Co.,Ltd. +8615271838296 China 1534 58 Inquiry
Chongqing Zhihe Biopharmaceutical Co., Ltd. +86-18580541567 +86-17782035140 China 301 58 Inquiry
Hebei Saisier Technology Co., LTD +86-18400010335 +86-18034520335 China 989 58 Inquiry

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