HEMOGLOBIN
- CAS No.
- 9008-02-0
- Chemical Name:
- HEMOGLOBIN
- Synonyms
- MU;HB;GST1;GTH4;GTM1;PMSA2;PSMA2;C01708;HB, BABOON;HEMOGLOBIN
- CBNumber:
- CB3741179
- Molecular Formula:
- C13H10N2O2
- Molecular Weight:
- 226.2307
- MOL File:
- 9008-02-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/24 15:52:23
| storage temp. | 2-8°C |
|---|---|
| solubility | 0.6 M HCl: soluble20mg/mL |
| form | substrate powder |
| color | Dark brown powder |
| Water Solubility | Soluble in water. |
| EPA Substance Registry System | Hemoglobins (9008-02-0) |
HEMOGLOBIN price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | H7379 | Hemoglobin human lyophilized powder | 9008-02-0 | 1G | ₹7381.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H7379 | Hemoglobin human lyophilized powder | 9008-02-0 | 5G | ₹21411.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | WH0002944M1 | Monoclonal Anti-GSTM1 antibody produced in mouse clone 3B10, purified immunoglobulin, buffered aqueous solution | 9008-02-0 | 100μG | ₹48018.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H7379 | Hemoglobin human lyophilized powder | 9008-02-0 | 10G | ₹36785.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | H4131 | Hemoglobin porcine lyophilized powder | 9008-02-0 | 1G | ₹3674.1 | 2022-06-14 | Buy |
HEMOGLOBIN Chemical Properties,Uses,Production
Description
Haemoglobin, the oxygen-transport protein in the red blood cells, is a tetramer and each of the four chains
contains a haeme group. It is interesting to note that the four haeme groups in haemoglobin do not operate
independently. The release (and binding) of oxygen is a cooperative process, which means that the loss
(uptake) of the first oxygen molecule triggers the release of the remaining three.
The current model for oxygen binding in haemoglobin and myoglobin can be explained in the following
way. The deoxy form contains a high-spin Fe(II) centre, which, because of its size, does not form a plane with
its four nitrogen donor atoms. Instead, it is located slightly above the plane, drawn towards the His residue.
Once oxygen enters trans to the His residue, the iron centre is oxidised to a low-spin Fe3+ centre and O2 is
reduced to [O2]-. Both species contain an unpaired electron. The low-spin Fe3+ moves into the plane and
pulls the His residue down. This affects the remaining protein chain and triggers the uptake/release of oxygen
in the other three haeme groups.
Uses
Medicine, usually called hemoglobin.
Definition
The respiratory protein of the red blood cells, it transfers oxygen from the lungs to the tissues and carbon dioxide from the tissues to the lungs. Its affinity for carbon monoxide is >200 times that for oxygen. Hemoglobin is a conjugated protein of molec
General Description
Native hemoglobin from bovine erythrocytes. A major oxygen-transporting component of red blood cells that is also nitric oxide scavenger. Blocks carbachol-stimulated cGMP production. This preparation contains primarily Ferric-hemoglobin and must be reduced to the ferrous form to bind molecular oxygen. Note: this preparation contains primarily ferric-hemoglobin and must be reduced to the ferrous form to bind molecular oxygen.
Purification Methods
Purify it from blood using CM-32 cellulose column chromatography. [Matsukawa et al. J Am Chem Soc 107 1108 1985.] For the purification of the and chains see Hill et al. Biochemical Preparations 10 55 1963. Histones (from S4A mouse lymphoma). The purification of histones uses a macroprocess column, heptafluorobutyric acid as solubilising and ion-pairing agent and an acetonitrile gradient. [McCroskey et al. Anal Biochem 163 427 1987.]
HEMOGLOBIN Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Loba Chemie Pvt Ltd | +91-22-6663 6663 | Mumbai, India | 498 | 58 | Inquiry |
| Arun & Co. | 91-22-67723000 | Maharashtra, India | 15 | 58 | Inquiry |
| Arun & Company | +91-22-6772 3000 | Mumbai, India | 5 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Central Drug House(P) Ltd. | 58 |
| LOBA CHEMIE PVT.LTD. | 58 |
| Triveni chemicals | 58 |
| Loba Chemie Pvt Ltd | 58 |
| Arun & Co. | 58 |
| Arun & Company | 58 |
| CLEARSYNTH LABS LTD. | 58 |
Related articles
- Hemoglobin synthesis and Low effects of hemoglobin
- Hemoglobin is a protein containing iron that facilitates the transport of oxygen in red blood cells. Almost all vertebrates co....
- Jul 24，2024
- Hemoglobin: Unveiling Allosteric Mechanisms for Enhanced Oxygen Transport
- Hemoglobin transports oxygen in vertebrates, modulated by allosteric effects and structural changes, essential for developing ....
- Mar 20，2024
- What is a Normal Hemoglobin Level?
- A hemoglobin test measures the amount of hemoglobin in the blood. Hemoglobin is a protein in red blood cells that transports o....
- Dec 28，2022
9008-02-0(HEMOGLOBIN)Related Search:
1of4
chevron_right