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Chorionic Gonadotropin

Chorionic Gonadotropin Structure
CAS No.
9002-61-3
Chemical Name:
Chorionic Gonadotropin
Synonyms
HCG;HUMAN CHORIONIC GONADOTROPIN;LHA;HUMAN CHORIONIC GONADOTROPHIN;apl;pregnyl;HCG 5000IU;choragon;CHORIONIC GONADOTROPIN HUMAN;HGG
CBNumber:
CB8353322
Molecular Formula:
C17H28
Molecular Weight:
232.40422
MOL File:
9002-61-3.mol
Modify Date:
2024/7/2 8:55:27

Chorionic Gonadotropin Properties

storage temp. 2-8°C
solubility H2O: soluble1ML/vial
form lyophilized powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P281
Hazard Codes  B,Xn
Risk Statements  63-62
Safety Statements  22-36-36/37
WGK Germany  3
RTECS  MD6953000
HS Code  2937190000

Chorionic Gonadotropin price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) CG5 Chorionic gonadotropin human lyophilized powder, vial of ~5,000?IU 9002-61-3 1VIAL ₹15685.43 2022-06-14 Buy
Sigma-Aldrich(India) CG5 Chorionic gonadotropin human lyophilized powder, vial of ~5,000?IU 9002-61-3 10VIALS ₹94610.5 2022-06-14 Buy
Sigma-Aldrich(India) CG10 Chorionic gonadotropin human lyophilized powder, vial of ~10,000?IU 9002-61-3 1VIAL ₹20708.23 2022-06-14 Buy
Sigma-Aldrich(India) CG10 Chorionic gonadotropin human lyophilized powder, vial of ~10,000?IU 9002-61-3 10VIALS ₹130116.5 2022-06-14 Buy
Sigma-Aldrich(India) C8554 Chorionic gonadotropin human lyophilized powder, suitable for mouse embryo cell culture 9002-61-3 50IU ₹7848.13 2022-06-14 Buy
Product number Packaging Price Buy
CG5 1VIAL ₹15685.43 Buy
CG5 10VIALS ₹94610.5 Buy
CG10 1VIAL ₹20708.23 Buy
CG10 10VIALS ₹130116.5 Buy
C8554 50IU ₹7848.13 Buy

Chorionic Gonadotropin Chemical Properties,Uses,Production

Chemical Properties

White or yellowish-white, amorphous powder.

Uses

Chorionic gonadotropin human has been used:

  • to induce oocyte maturation in cultured follicles
  • along with pregnant mare serum gonadotropin (PMSG) to induce superovulation in mice
  • as medium component for fetal testes culture to aid steroidogenic responsiveness

Production Methods

CG is produced in the chorion.

Application

Human chorionic gonadotropin (hCG) is a chemical produced by the trophoblast tissue, which is usually present in the early embryo and will eventually become part of the placenta. Measuring hCG levels helps to identify normal, pathological and miscarried pregnancies. Measuring hCG is also beneficial for many cancers including choriocarcinoma and extrauterine malignancies.

General Description

Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.

Clinical Use

Choriogonadotropin alfa is obtained by rDNA technology and is biologically and chemically identical to hCG of natural origin. It is used, like hCG of natural origin, for inducing ovulation in women with anovulatory infertility. Following proper pretreatment with a GnRH antagonist or superagonist to desensitize the pituitary, women participating in ART are treated with a folliclestimulating agent (e.g., menotropins) to effect the final maturation of the follicles within the ovaries. Ultrasonograms are used to determine proper follicle maturation before the administration of choriogonadotropin alfa to induce ovulation. A distinct advantage of this product is that it can be self-administered by the patient via SC injection.

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