NEMONAPRIDE
![NEMONAPRIDE Structure](CAS/GIF/75272-39-8.gif)
- CAS No.
- 75272-39-8
- Chemical Name:
- NEMONAPRIDE
- Synonyms
- C12915;Emilace;ym-09151;emonapride;YM 09151-2;NEMONAPRIDE;nobenzamide;inobenzamide;(2R,3R)-nemonapride;cis-(+-)-rrolidinyl)
- CBNumber:
- CB3492220
- Molecular Formula:
- C21H26ClN3O2
- Molecular Weight:
- 387.9
- MOL File:
- 75272-39-8.mol
- Modify Date:
- 2023/6/30 15:45:59
Melting point | 152-153°C |
---|---|
storage temp. | Store at RT |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
color | White to Off-White |
CAS DataBase Reference | 75272-39-8 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
NFPA 704 |
|
NEMONAPRIDE Chemical Properties,Uses,Production
Description
Nemonapride is a potent dopamine D2receptor antagonist antipsychotic reported to have superior efficacy against hallucinations and delusions and also to be effective in the treatment of negative symptoms. The compound is a benzamide diastereomer and, although more potent than haloperidol, side effects are reported to be few primarily akinesia and some muscle rigidity with extrapyramidal symptoms being rare.
Chemical Properties
Colourless Crystalline Solid
Uses
Nemonapride is a selective dopamine D2 receptor antagonist. Nemonapride is used as an antipsychotic.
Biological Activity
Highly potent dopamine D 2 -like receptor antagonist; selective over D 1 -like receptors (K i values are 0.1 and 740 nM for D 2 -like and D 1 -like receptors respectively). Also potent 5-HT 1A receptor agonist (IC 50 = 34 nM) and has affinity for sigma receptors.
NEMONAPRIDE Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
Nantong Hanfang Biotechnology Co. , Ltd. | 18616537568 | China | 30968 | 58 | Inquiry |
TargetMol Chemicals Inc. | 4008200310 | China | 23962 | 58 | Inquiry |
Cayman Chemical Company | (800) 364-9897 | United States | 6618 | 81 | Inquiry |
Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | China | 8739 | 58 | Inquiry |
BOC Sciences | USA | 0 | 65 | Inquiry | |
BIOTREND Chemicals AG | +41 44 805 76 76 | Germany | 1250 | 62 | Inquiry |
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