N,N-DIETHYLNICOTINAMIDE
- CAS No.
- 59-26-7
- Chemical Name:
- N,N-DIETHYLNICOTINAMIDE
- Synonyms
- NIKETHAMIDE;Nikotin;CORVOTONE;Tonocard;nicor;Ni-Cor;Ecoran;Corivo;Cormed;Cormid
- CBNumber:
- CB3677171
- Molecular Formula:
- C10H14N2O
- Molecular Weight:
- 178.23
- MOL File:
- 59-26-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/12 15:32:57
| Melting point | 23 °C (lit.) |
|---|---|
| Boiling point | 296-300 °C (lit.) |
| Density | 1.06 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | pKa 3.46(H2O,t =20) (Uncertain) |
| form | Liquid |
| color | Clear colorless to yellow |
| Merck | 14,6543 |
| BRN | 5743 |
| InChI | InChI=1S/C10H14N2O/c1-3-12(4-2)10(13)9-6-5-7-11-8-9/h5-8H,3-4H2,1-2H3 |
| InChIKey | NCYVXEGFNDZQCU-UHFFFAOYSA-N |
| SMILES | C1=NC=CC=C1C(N(CC)CC)=O |
| CAS DataBase Reference | 59-26-7(CAS DataBase Reference) |
| EPA Substance Registry System | Nikethamide (59-26-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H319 |
| Precautionary statements | P264-P270-P280-P301+P310-P305+P351+P338-P337+P313 |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38-23/24/25 |
| Safety Statements | 26-45-36/37/39 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | QS4375000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 29333999 |
| Toxicity | LD50 i.p. in rats: 272 mg/kg (Goldenthal) |
N,N-DIETHYLNICOTINAMIDE price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D98807 | N,N-Diethylnicotinamide 99% | 59-26-7 | 25G | ₹3864.53 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D98807 | N,N-Diethylnicotinamide 99% | 59-26-7 | 100G | ₹8519.28 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | D98807 | N,N-Diethylnicotinamide 99% | 59-26-7 | 500G | ₹31933.75 | 2022-06-14 | Buy |
N,N-DIETHYLNICOTINAMIDE Chemical Properties,Uses,Production
Description
A further Corydalis alkaloid, coramine has been obtained from C. pseudoadunca M. Pop. It forms colourless needles from EtOH and is optically active with a specific rotation of [α]D - 391 ° (c 0.2, MeOH). Both the hydrochloride, m.p. 216-9°C and the hydrobromide, m.p. 223-6°C have been described.
Chemical Properties
clear colorless to yellow liquid
Uses
analeptic
Application
N,N-Diethylnicotinamide (DENA) is one of the central respiratory stimulants and is used in the study of respiratory failure. DENA is also an excellent hydrophilic agent for paclitaxel (PTX) and improves the water solubility of PTX.
General Description
Clear light yellow viscous liquid or crystalline solid. Slightly bitter taste followed by a faint sensation of the warmth.
Air & Water Reactions
Water soluble.
Reactivity Profile
N,N-DIETHYLNICOTINAMIDE is incompatible with sodium carbonate solutions which cause precipitation. .
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition N,N-DIETHYLNICOTINAMIDE emits toxic fumes.
Fire Hazard
N,N-DIETHYLNICOTINAMIDE is combustible.
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic fumes of NOx.
References
Yunusov, Akramov, Yunusov, Dokl. Akad. Nauk. USSR, 162,607 (1965)
Yunusov, Akramov, Yunusov, Khim. Prir. Soedin., 2, 340 (1966)
Ibragimova, Yunusov, Yunusov, ibid, 6,438 (1970)
Yunusov, et al., ibid, 7, 380 (1971)
N,N-DIETHYLNICOTINAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Sai Siddhi | 07942551420 | Gujarat, India | 95 | 58 | Inquiry |
| Laksh Finechem Private Limited | +91-8048600905 | Gujarat, India | 195 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Pharmaffiliates Analytics & Synthetics (P) Ltd. | 91-172-5066494 | Haryana, India | 631 | 58 | Inquiry |
| Argos International | 08048372395Ext 118 | Mumbai, India | 154 | 58 | Inquiry |
59-26-7(N,N-DIETHYLNICOTINAMIDE)Related Search:
1of4
chevron_right