Fenoldopam mesylate
- CAS No.
- 67227-57-0
- Chemical Name:
- Fenoldopam mesylate
- Synonyms
- SKF R-82526;9CL-CORLOPAM;(S)-SKF-82526;(R)-SKF-82526;CORLOPAM MESYLATE;Fenodopam mesylate;SKF-82526 mesylate;FENOLDOPAM MESYLATE;FENOLDIPAM MESYLATE;FENOLDOPAM METHANESULFONATE
- CBNumber:
- CB3729841
- Molecular Formula:
- C17H20ClNO6S
- Molecular Weight:
- 401.86
- MOL File:
- 67227-57-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/8 9:02:20
| Melting point | 274° (dec) |
|---|---|
| storage temp. | room temp |
| solubility | DMSO: ≥15mg/mL at ~60°C |
| form | powder |
| color | white to tan |
| InChIKey | WOFIIEUMIDZJEJ-UHFFFAOYSA-N |
| CAS DataBase Reference | 67227-57-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317-H319 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P305+P351+P338 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36-42/43 | |||||||||
| Safety Statements | 22-26-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 2933995300 | |||||||||
| NFPA 704 |
|
Fenoldopam mesylate price More Price(2)
Fenoldopam mesylate Chemical Properties,Uses,Production
Description
Fenoldopam, first approved in the Netherlands in 1992, ended by reaching its first market, the US, for the short-term management of severe hypertension, including malignant hypertension, in the hospital setting. Fenoldopam can be prepared in 3 steps from the corresponding phenethylamine and aryloxiran, the pivotal step being the cyclisation in benzazepine in acidic medium. Fenoldopam is a potent dopamine D1 receptor agonist acting peripherally to produce systemic vasodilation.As it does not cross the bloodbrain barrier, it does not exert significant central dopaminergic activity. Fenoldopam also interacts significantly with 5HT1c and 5HT2 receptors. In comparative trials with the most common drug used for this condition in Europe, Fenoldopam was found to be appreciably more potent than nifedipine. Furthermore, Fenoldopam is fast acting and maintains a long-lasting antihypertensive effect.
Chemical Properties
White to Off-White Solid
Uses
Fenoldopam mesylate may be used to study dopamine D1-mediated cell signaling.
Fenoldopam mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Sharma Medicare Private Limited | 09810526765 | Uttar Pradesh, India | 2 | 58 | Inquiry |
| WESTON MEDICAL STORES | 08048250474Ext 432 | Punjab, India | 9 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29888 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49392 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |