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ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Analytical Standards >CLORAZEPATE DIPOTASSIUM SALT

CLORAZEPATE DIPOTASSIUM SALT

CLORAZEPATE DIPOTASSIUM SALT Structure
CAS No.
57109-90-7
Chemical Name:
CLORAZEPATE DIPOTASSIUM SALT
Synonyms
Azene;cm4306;cb4306;4306cb;ah3232;mendon;ab35616;latekoh;tr19119;belseren
CBNumber:
CB3737547
Molecular Formula:
C16H13ClK2N2O4
Molecular Weight:
410.94
MOL File:
57109-90-7.mol
Modify Date:
2023/5/15 10:44:01
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CLORAZEPATE DIPOTASSIUM SALT Properties

Melting point 228-235°C
Flash point 11 °C
storage temp. 2-8°C
solubility Freely soluble to very soluble in water, very slightly soluble in alcohol, practically insoluble in methylene chloride. Solutions in water and in alcohol are unstable and are to be used immediately.
form Solid
color White to Pale Yellow
EPA Substance Registry System Clorazepate dipotassium (57109-90-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H302-H361
Precautionary statements  P280-P301+P312+P330
Hazard Codes  Xn,T,F
Risk Statements  22-63-39/23/24/25-23/24/25-11
Safety Statements  22-36/37/39-45-36/37-16-7
RIDADR  3249
WGK Germany  3
RTECS  DE8750000
HazardClass  6.1(b)
PackingGroup  III
HS Code  2933910000
Toxicity LD50 in mice (mg/kg): 700 orally; 290 i.p.; LD50 orally in rats: >1000 mg/kg (Brunaud)

CLORAZEPATE DIPOTASSIUM SALT Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid

Uses

Anxiolytic. Controlled substance (depressant).

Definition

ChEBI: The compound of monopotassium clorazepate with potassium hydroxide. It is used for the management of anxiety disorders, for the short-term relief of anxiety, as adjunctive therapy in the management of epilepsy, and for the symptomatic relief of acute alcoh l withdrawal.

General Description

Clorazepate dipotassium,7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid dipotassium salt monohydrate(Tranxene), can be considered a prodrug. Inactive itself, itundergoes rapid decarboxylation by the acidity of thestomach to nordazepam (a major active metabolite of diazepam),which has a long half-life and undergoes hepaticconversion to active oxazepam. Despite the polar characterof the drug as administered, because it is quickly convertedin the GI tract to an active nonpolar compound, it has aquick onset, overall long half-life, and shares similar clinicaland pharmacokinetic properties to chlordiazepoxideand diazepam.

CLORAZEPATE DIPOTASSIUM SALT Preparation Products And Raw materials

Raw materials

Potassium hydroxide 2-Amino-5-chlorobenzonitrile Magnesium

Preparation Products

57109-90-7(CLORAZEPATE DIPOTASSIUM SALT)Related Search:

Clorazepate-metabolite Clorazepate (break down) Benzophenone imine 2,3-Diaminopropionic acid N-BENZYLIDENEISOPROPYLAMINE
3-Amino-L-alanine hydrochloride 3-PHENYLAMINO-PROPIONIC ACID CLORAZEPATE DIPOTASSIUM SALT Oxalic acid Potassium oxalate monohydrate
Oxalic acid dihydrate 3-[(4-chlorophenyl)amino]propanoic acid (+/-)-BMAA HYDROCHLORIDE (SYNTHETIC) SYN THETIC PREPARATION BENZHYDRYLIDENE METHYLAMINE clorazepate monopotassium,Clorazepate depot,Monopotassium clorazepate
CLORAZEPATE DIPOTASSIUM CLORAZEPATE -*LIST IV DIPOTASSIUM CLORAZEPATE - REFERENCE SPECTRUM
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Chlorazepate dipotassic Potassium hydroxide (K(OH)), compd. with 7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid monopotassium salt (1:1) (9CI) Potassium hydroxide, compd. with 7-chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid monopotassium salt (1:1) chlorazepate chlorazepatedipotassium clorazepatedipotassium cm4306 Clorazepate dipotassium salt solution Clorazepate Dipotassium CIV (125 mg) belseren bipotassiumchlorazepate cb4306 chlorazepam 7-Chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid Apo-Clorazepate Azene Clorazepate potassium Gen-xene Novo-Clopate Nu-Clopate Tranzene CLORAZEPATE DIPOTASSIUM METHANOL*SOLUTIO N CLORAZEPATE DIPOTASSIUM--DEA SCHEDULE I& 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, monopotassium salt, compd. with potassium hydroxide (K(OH)) (1:1) [2-Phenyl-2-(2-amino-5-chlorophenyl)-1-azavinyl]malonic acid 1H-1,4-Benzodiazepine-3-carboxylic acid, 7-chloro-2,3-dihydro-2-oxo-5-phenyl-, monopotassium salt, compd. with potassium hydroxide (1:1) tranxene tranxilen tranxilene tranxilium Clorazepate dipotassium solution 7-CHLORO-2,3-DIHYDRO-2,2-DIHYDROXY-5-PHENYL-1H-1,4-BENZODIAZEPINE-3-CARBOXYLIC ACID DIPOTASSIUM SALT Clorazepic acid dipotassium salt Clorazepate dipotassium salt,7-Chloro-2,3-dihydro-2,2-dihydroxy-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid Clorazepic Acid DipotasiuM Salt CLORAZEPATE CLORAZEPATE DIPOTASSIUM SALT 4306cb ab35616 abbott-35616 ah3232 dipotassiumchlorazepate dipotassiumclorazepate latekoh mendon monopotassiumsalt,compd.withpotassiumhydroxide nevracten potassium7-chloro-2,3-dihydro-2-oxo-5-phenyl-1h-1,4-benzodiazepine-3-carboxy tencilan tr19119 transene transilium QCHSEDTUUKDTIG-UHFFFAOYSA-L Potassium (3RS)-7-chloro-2-oxo-5-phenyl-2,3-dihydro-1H- 1,4-benzodiazepine-3-carboxylate compound with potassium hydroxide (1:1) Dipotsium Clorazepate Dipotassium Clorazepate API 57109-90-7 C16H11ClN2O4K2