EC 1.6.4.2

EC 1.6.4.2 Structure
CAS No.
9001-48-3
Chemical Name:
EC 1.6.4.2
Synonyms
GR;GLUTATHIONE REDUCTASE;GR TYPE VI;GR TYPE II;EC 1.8.1.7;EC 1.6.4.2;EC: 1.6.4.2;E.C. 1.8.1.7;GSH reductase;GSSG reductase
CBNumber:
CB3770126
Molecular Formula:
NULL
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2023/4/23 13:52:06

EC 1.6.4.2 Properties

storage temp. 2-8°C
form suspension (aqueous)
color yellow
EPA Substance Registry System Reductase, glutathione (9001-48-3)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P284-P501
Safety Statements  24/25
WGK Germany  3
10

EC 1.6.4.2 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) G3664 Glutathione Reductase from baker''s yeast (S. cerevisiae) ammonium sulfate suspension, 100-300?units/mg protein (biuret) 9001-48-3 100UNITS ₹3108 2022-06-14 Buy
Sigma-Aldrich(India) G3664 Glutathione Reductase from baker''s yeast (S. cerevisiae) ammonium sulfate suspension, 100-300?units/mg protein (biuret) 9001-48-3 500UNITS ₹11222.1 2022-06-14 Buy
Sigma-Aldrich(India) G9297 Glutathione Reductase human buffered aqueous solution, ≥10?units/mg protein, recombinant, expressed in E. coli 9001-48-3 500μG ₹34809.6 2022-06-14 Buy
Sigma-Aldrich(India) G3664 Glutathione Reductase from baker''s yeast (S. cerevisiae) ammonium sulfate suspension, 100-300?units/mg protein (biuret) 9001-48-3 2500UNITS ₹42180 2022-06-14 Buy
Product number Packaging Price Buy
G3664 100UNITS ₹3108 Buy
G3664 500UNITS ₹11222.1 Buy
G9297 500μG ₹34809.6 Buy
G3664 2500UNITS ₹42180 Buy

EC 1.6.4.2 Chemical Properties,Uses,Production

Uses

Human glutathione reductase has been used in:

  • glutathione reductase activity assay
  • oxidative stress analysis
  • redox assays

General Description

Glutathione reductase (GLR1) exists in mitochondrial and cytoplasmic isoforms. It shares sequence and structural homology to thioredoxin reductase, and is a flavin-containing oxidoreductase. Its active site is composed of a redox-active disulphide, and it requires NADPH for its catalytic activity. It is a widely present enzyme and is found in plants, bacteria, yeast, mice and humans.

Biochem/physiol Actions

Glutathione reductase IGR) is a crucial flavoenzyme in the antioxidant defense system. Reduced glutathione (GSH) is used by glutathione peroxidase to detoxify hydrogen peroxide and in the process is converted to oxidized glutathione (GSSG). The GSSG is then recycled back to GSH by glutathione reductase (GR) using NADPH that is then converted to NADP+. The regenerated GSH is then available to detoxify more hydrogen peroxide. The enzyme uses FAD as a cofactor. GR and glutathione peroxidase may inhibit lipid peroxidation by functioning as antioxidant enzymes in sperm. Glutathione reductase shares a structural motif with a number of other proteins including aspartyl proteases, citrate synthase, EF hands, hemoglobins, lipocalins, and α/β hydrolases. GR is stimulated by melatonin and is reportedly irreversibly inhibited by a number of oxygen radical generating systems.

EC 1.6.4.2 Preparation Products And Raw materials

Raw materials

Preparation Products

EC 1.6.4.2 Suppliers

Global( 109)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
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NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE II NAD[P]H: OXIDIZED-GLUTATHIONE OXIDOREDUCTASE TYPE VI GR TYPE II GR TYPE VI NADP-dependent glutathione reductase NADPH-glutathione reductase NADPH-GSSG reductase E.C. 1.8.1.7 EC 1.8.1.7 Glutathione disulfide oxidoreductase Glutathione S-reductase GSH reductase GLUTATHIONE REDUCTASE TYPE II GLUTATHIONE REDUCTASE TYPE VI GLUTATHIONE REDUCTASE, YEAST EC 1.6.4.2 EC: 1.6.4.2 Glutathione Reductase bakers yeast (S. cerevisiae) glutathione reductase from baker'S yeast Reductase, glutathione GLUTATHIONE REDUCTASE TYPE VI FROM*SPINA CH GLUTATHIONE REDUCTASE TYPE II CRUDE*FROM WHEAT GERM GLUTATHIONE REDUCTASE FROM BAKER'S YEAST , ~100 U/MG GLUTATHIONE REDUCTASE FROM BAKER'S & GlutathioneReductaseExYeast(E.C.1.6.4.2) Glutathionereductaseexyeast glutathione reductase from baker's yeast (s. cerevisiae) glutathione reductase from spinach glutathione reductase from wheat germ Glutathione Reductase from baker's yeast (S. cerevisiae),GR, NAD(P)H:oxidized-glutathione oxidoreductase Glutathione Reductase from spinach,GR, NAD(P)H: oxidized-glutathione oxidoreductase Glutathione reductase (NAD(P)H) from Yeast, 50% glycerol solution GR, (NAD(P)H): oxidized-glutathione oxidoreductase GR/Glutathione Reductase froM baker's yeast Glutathione Reductase human GSSG reductase Glutathione Reductase from bovine intestinal mucosa Glutathione reductase from E. coli, Recombinant Native Spinach Glutathione Reductase Native Wheat germ Glutathione Reductase Native Bakers yeast (S. cerevisiae) Glutathione Reductase Glutathione Reductase from Human, Recombinant Glutathione Reductase, from Yeast[GR] Glutathionereductase, 189units/mg protein GR GLUTATHIONE REDUCTASE Glutathione Reductase from baker's yeast 9001-48-3 General Metabolic Enzymes A-H General Metabolic Enzymes Metabolomics BioChemical enzyme