oxophenarsine

oxophenarsine Structure
CAS No.
306-12-7
Chemical Name:
oxophenarsine
Synonyms
Oxarsan;Phenarsen;Brn 3235865;oxophenarsine;Einecs 206-178-8;2-Amino-4-arsenosophenol;Phenol, 2-amino-4-arsenoso-;538-03-4 (Mono-hydrochloride);3-Amino-4-hydroxyphenylarsinoxide;63951-03-1 (Mono-hydrochloride salt)
CBNumber:
CB3907632
Molecular Formula:
C6H6AsNO2
Molecular Weight:
199.04
MOL File:
306-12-7.mol
Modify Date:
2023/5/4 17:34:37

oxophenarsine Properties

Melting point 133°C (rough estimate)
Boiling point 117.4°C
form solid
color Bright-yellow deliquescent powder or white crystals

SAFETY

Risk and Safety Statements

Toxicity LDLo orl-mus: 150 mg/kg JPETAB 76,358,42

oxophenarsine Chemical Properties,Uses,Production

Industrial uses

Palladium dissolves in hot oxidising acids. Palladium is used as a hydrogenation catalyst, for H2/D2/T2separation and purification as well as a catalyst in the Wacker process. The Wacker process, which facilitates the oxidation of ethylene to acetaldehyde, was the first organopalladium reaction that was applied on an industrial scale.

Safety Profile

Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of NOx and As

Enzyme inhibitor

This sulfhydryl-reactive arsenical (FW = 199.04 g/mol; CAS 306-12-7), variously named Mapharsen, Ehrlich-5, oxyphenarsine, oxarsan, arsinoxide, 3-amino-4-hydroxybenzenearsenoxide, and 2-amino-4-arsenosophenol, was originally developed by Nobelist Paul Ehrlich as an anti-syphilis drug. (Note: do not confuse this compound with oxophenylarsine, also known phenylarsine oxide). It is now used as an antiprotozomal agent, particularly against Trypanosoma. Oxophenarsine is typically supplied as the hydrochloride (FW = 235.50 g/mol) and is readily soluble in water. (See also Dichlorophenarsine) Target(s): acetyl-CoA acyltransferase; actomyosin ATPase; aldehyde dehydrogenase; alkaline phosphatase; asparagine synthetase; ATPase, rat brain; ATPase, trypanosomal; cathepsin; cholinesterase; deoxyribonuclease; diisopropylfluorophosphatase; γ-glutamyl hydrolase, or pteroylglutamate conjugase; glyceraldehyde-3-phosphate dehydrogenase; a-glycerophosphate oxidase; hexokinase; myosin ATPase; pyrophosphatase; pyruvate decarboxylase; pyruvate oxidase; ribose-5-phosphate isomerase; succinate dehydrogenase; succinate oxidase; urease.

oxophenarsine Preparation Products And Raw materials

Raw materials

Preparation Products

oxophenarsine Suppliers

Global( 4)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Shanghai New Union Textra Import & Export Co., Ltd +861-348-227-9455 China 2752 60 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Portail Substances Chimiques 10 20 0000 France 6027 58 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051 China 9968 58 Inquiry
2-Amino-4-arsenosophenol Oxarsan Phenarsen (3-Amino-4-hydroxyphenyl)arsenous acid 3-Amino-4-hydroxyphenylarsinoxide 538-03-4 (Mono-hydrochloride) 63951-03-1 (Mono-hydrochloride salt) Brn 3235865 Einecs 206-178-8 oxophenarsine Phenol, 2-amino-4-arsenoso- 306-12-7 C6H6AsNO2