ACETARSONE
- CAS No.
- 97-44-9
- Chemical Name:
- ACETARSONE
- Synonyms
- svc;190f;f190;goyl;mexyl;amasan;Oracid;Amassn;Qsarsal;Qrarsan
- CBNumber:
- CB3485369
- Molecular Formula:
- C8H10AsNO5
- Molecular Weight:
- 275.09
- MOL File:
- 97-44-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/21 10:59:17
| Melting point | 220.5°C |
|---|---|
| Boiling point | 72.17°C |
| Density | 1.0325 g/cm3(Temp: 15 °C) |
| storage temp. | Store at RT |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | solid |
| pka | pKa 3.73 (H2O t=26) (Uncertain);7.9 (Uncertain); 9.3(H2O) (Uncertain) |
| color | Crystalline material |
| Merck | 13,53 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS09,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H410-H301+H331 |
| Precautionary statements | P273-P391-P501 |
| Hazard Codes | T,N |
| Risk Statements | 23/25-50/53 |
| Safety Statements | 20/21-28-45-60-61 |
| RIDADR | UN 3465 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | CF8400000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | MLD in rabbits, cats (mg/kg): 125-150, 150-175 orally (Anderson, Leake) |
ACETARSONE Chemical Properties,Uses,Production
Uses
antiprotozoal; diethylamine salt as antiphilitic
World Health Organization (WHO)
Acetarsol, which has antiprotozoal and antitrichomonal activity, has largely been discarded for systemic use because of its potential to cause systemic poisoning. However, topical preparations for vaginal trichomoniasis are still available and it is included in low concentrations (equal to or less than 0.45%) in some medicated toothpastes.
Safety Profile
Poison by ingestion and intravenous routes. Human systemic effects by ingestion: respiratory system, endocrine system, dermatitis, and fever. Human systemic effects by intravagmal route: hallucinations, dlstorted perceptions, convulsions, nausea or vomiting, decreased urine volume, and fever. Mutation data reported. See also ARSENIC COMPOUNDS. When heated to decomposition it emits very toxic fumes of NOx, and As
Purification Methods
It crystallises from water in colourless prisms. It decomposes slowly on prolonged boiling in H2O or dilute alkalis. The N-propionyl derivative recrystallises from H2O with m 228-229o(dec). [Raiziss & Fisher J Am Chem Soc 48 1323 1926, Hewitt & King J Chem Soc 823 1926, Beilstein 16 I 491, 16 II 521, 16 III 1129.]
ACETARSONE Preparation Products And Raw materials
Raw materials
Preparation Products
ACETARSONE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| DeFINE CHEMICALS | +91-8010769889 +91-9320057099 | Maharashtra, India | 120 | 58 | Inquiry |
| Montage Chemicals Pvt Ltd | +91-9320157886 +91-9320157886 | Maharashtra, India | 27 | 58 | Inquiry |
| Montage Chemicals Pvt. Ltd. | 08048372747Ext 551 | Maharashtra, India | 33 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | China | 6934 | 58 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 26165 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Wuhan Yuanxing Biomedical Technology Co., Ltd | 027-8558552 15927172400 | China | 2937 | 58 | Inquiry |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | China | 10529 | 58 | Inquiry |
| Wuhan lanabai Pharmaceutical Chemical Co., Ltd | 15307151931 | China | 8149 | 58 | Inquiry |
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