piperylone

piperylone Structure
CAS No.
2531-04-6
Chemical Name:
piperylone
Synonyms
PR66;piperylone;Piperylonum;4-ethyl-2-(1-methyl-4-piperidyl)-5-phenyl-1H-pyrazol-3-one;4-ethyl-2-(1-methylpiperidin-4-yl)-5-phenyl-1H-pyrazol-3-one;4-Ethyl-1,2-dihydro-2-(1-methylpiperidin-4-yl)-5-phenyl-3H-pyrazol-3-one;3H-Pyrazol-3-one, 4-ethyl-1,2-dihydro-2-(1-methyl-4-piperidinyl)-5-phenyl-
CBNumber:
CB3941405
Molecular Formula:
C17H23N3O
Molecular Weight:
285.38
MOL File:
2531-04-6.mol
MSDS File:
SDS
Modify Date:
2023/5/21 10:59:17

piperylone Properties

Boiling point 413.0±55.0 °C(Predicted)
Density 1.121±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka pK1 5.90; pK2 9.15(at 25℃)

piperylone Chemical Properties,Uses,Production

Originator

Palerol, Novartis

Manufacturing Process

A mixture of 8.8 parts of α-ethylbenzoylacetic acid ethyl ester and 5,3 parts of N-methyl-piperidyl-4-hydrazine is allowed to stand for 30 min at 22°C, after which the mixture is heated for 5 hours to 130°C under a pressure of 12 mm. After 4 hours 1-(N-methylpiperidyl-4)-3-phenyl-4-ethylpyrazolone-5 begins crystallize out. The reaction mixture is allowed to cool, after which the crystal mass is triturated with ether and then recrystallized from methanol-ether or from acetone. Melting point 159-161°C.

Therapeutic Function

Analgesic

piperylone Preparation Products And Raw materials

Raw materials

Preparation Products

piperylone Suppliers

Global( 9)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
kemikalieimport + 45 - 2034 3359 Europe 6699 47 Inquiry
ecochem international chemical broker +45 45 42 34 36 Europe 6385 66 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
MedChemExpress 021-58955995 United States 6398 58 Inquiry
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223; China 29778 58 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 17691182729 18161915376 China 10011 58 Inquiry
piperylone Piperylonum 4-Ethyl-1,2-dihydro-2-(1-methylpiperidin-4-yl)-5-phenyl-3H-pyrazol-3-one 4-ethyl-2-(1-methyl-4-piperidyl)-5-phenyl-1H-pyrazol-3-one 4-ethyl-2-(1-methylpiperidin-4-yl)-5-phenyl-1H-pyrazol-3-one PR66 3H-Pyrazol-3-one, 4-ethyl-1,2-dihydro-2-(1-methyl-4-piperidinyl)-5-phenyl- 2531-04-6