PROCATEROL HYDROCHLORIDE
![PROCATEROL HYDROCHLORIDE Structure](CAS/GIF/62929-91-3.gif)
- CAS No.
- 62929-91-3
- Chemical Name:
- PROCATEROL HYDROCHLORIDE
- Synonyms
- meptin;opc2009;Epcalol;Cateptin;Astoprotin;Carvedilol-d;PROCATEROL HCL;Einecs 263-763-0;Aficamten Impurity 26;Procaterol hydrochlorid
- CBNumber:
- CB4120391
- Molecular Formula:
- C16H23ClN2O3
- Molecular Weight:
- 326.82
- MOL File:
- 62929-91-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H361 |
Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
WGK Germany | 2 |
RTECS | VC8296000 |
PROCATEROL HYDROCHLORIDE Chemical Properties,Uses,Production
Description
Procaterol is an agonist of β2-adrenergic receptors (β2-ARs). It binds to (Kd = 46 pM), and is selective for, β2-ARs over β1-ARs (Kd = 4,000 pM). Procaterol binds more potently to β2-ARs in isolated guinea pig lung than to β1-ARs in isolated guinea pig cardiac ventricle in the presence (IC50s = 175 and 1,660 nM, respectively) and absence of GTP (; IC50s = 55.1 and 1,660 nM, respectively). It inhibits contractions induced by acetylcholine in isolated guinea pig trachea (EC50 = 10.5 nM). In vivo, procaterol inhibits histamine-induced airflow obstruction in a guinea pig model of ovalbumin-sensitized asthma when administered via inhalation at a dose of 10 μg/ml.
Uses
Procaterol Hydrochloride is a short-acting pulmonary β2-agonist for asthma treatment.
General Description
Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.
Biological Activity
Specific and very potent β 2 agonist.
PROCATEROL HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29897 | 58 | Inquiry |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | China | 6387 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
SIMAGCHEM CORP | +86-13806087780 | China | 17367 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 25298 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |