(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Structure
CAS No.
3862-25-7
Chemical Name:
(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Synonyms
7α-hydroxy-4-Cholesten-3-one;7alpha-hydroxycholest-4-en-3-one;7HCO;alpha-HC;7α-hydroxycholestenone;Δ4-7α-hydrocholesterol;7α-hydroxy cholestenone;4-CHOLESTEN-7α-OL-3-ONE;7a-Hydroxy-cholestene-3-one;7-Hydroxy-4-cholesten-3-one
CBNumber:
CB41235636
Molecular Formula:
C27H44O2
Molecular Weight:
400.64
MOL File:
3862-25-7.mol
Modify Date:
2023/5/18 11:31:04

(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Properties

Melting point 182-184°C
Boiling point 516.7±29.0 °C(Predicted)
Density 1.03±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka 14.49±0.70(Predicted)
color White to Off-White

(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Chemical Properties,Uses,Production

Description

7α-hydroxy-4-Cholesten-3-one is a metabolite of 7α-hydroxy cholesterol and an intermediate in the biosynthesis of bile acids. Plasma levels of 7α-hydroxy-4-cholesten-3-one positively correlate with the rate of bile acid synthesis in humans and are increased in patients following ileal resection.

Chemical Properties

White Solid

Uses

7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501).

Definition

ChEBI: A cholestanoid consisting of a cholesterol core having an oxo group at the 3-position, a C2C bond at the 4,5-position and an alpha-hydroxy group at the 7-position.

(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Preparation Products And Raw materials

(7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one Suppliers

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3862-25-7((7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one)Related Search:

7a-Hydroxy-cholestene-3-one 7 alpha-hydroxy-4-cholesten-3-one (7a)-7-Hydroxycholest-4-en-3-one 7a-Hydroxy-4-cholesten-3-one 7a-Hydroxycholest-4-en-3-one (7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one (7R,8S,9S,10R,13R,14S,17R)-7-hydroxy-10,13-diMethyl-17-((R)-6-Methylheptan-2-yl)-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one 7HCO 7Α-HYDROXY-4-CHOLESTEN-3-ONE;7Α-HYDROXYCHOLESTENONE;7HCO;ALPHA-HC;Α-HC 7α-hydroxycholestenone alpha-HC 7-Hydroxy-4-cholesten-3-one Δ4-7α-hydrocholesterol Cholest-4-en-3-one, 7-hydroxy-, (7α)- 7alpha-hydroxycholest-4-en-3-one 7α-hydroxy-4-Cholesten-3-one 7α-hydroxy cholestenone 2H7]-7-α-Hydroxy-4-cholesten-3-one 7α Hydroxy 4 cholesten 3 one,7αHydroxy4cholesten3one 4-CHOLESTEN-7α-OL-3-ONE 3862-25-7 Various Metabolites and Impurities Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals Steroids