4-Cholesten-3-one
- CAS No.
- 601-57-0
- Chemical Name:
- 4-Cholesten-3-one
- Synonyms
- CHOLESTENONE;4-Cholestenone;4-CHOLESTEN-3-ONE;3-Oxocholest-4-ene;3-OXO-4-CHOLESTENE;cholest-4-en-3-one;4-Cholestene-3-one;CHOLEST-4-ENE-3-ONE;3-KETO-4-CHOLESTENE;(+)-4-CHOLESTEN-3-ONE
- CBNumber:
- CB3222827
- Molecular Formula:
- C27H44O
- Molecular Weight:
- 384.64
- MOL File:
- 601-57-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/11/3 16:33:47
| Melting point | 79-82 °C |
|---|---|
| alpha | 92.5 º (c=2, CHCl3) |
| Boiling point | 451.27°C (rough estimate) |
| Density | 0.9717 (rough estimate) |
| refractive index | 1.5100 (estimate) |
| storage temp. | -20°C |
| solubility | Chloroform (Sparingly), Methanol (Slightly, Heated) |
| form | Solid |
| color | White to Off-White |
| optical activity | [α]23/D +91.0°, c = 2 in chloroform |
| Water Solubility | <0.5 g/L |
| BRN | 4707774 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 601-57-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Cholest-4-en-3-one(601-57-0) |
| EPA Substance Registry System | Cholest-4-en-3-one (601-57-0) |
SAFETY
Risk and Safety Statements
| Hazard statements | H413 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FZ7700000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29142900 | |||||||||
| NFPA 704 |
|
4-Cholesten-3-one price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 188174 | (+)-4-Cholesten-3-one 98% | 601-57-0 | 1G | ₹1948.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 188174 | (+)-4-Cholesten-3-one 98% | 601-57-0 | 10G | ₹7144.5 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C1366 | (+)-4-Cholesten-3-one min. 95.0 % | 601-57-0 | 5G | ₹5900 | 2022-05-26 | Buy |
4-Cholesten-3-one Chemical Properties,Uses,Production
Description
Cholestanone is a cholesterol metabolite that has a keto group in place of the 3-hydroxy group on cholesterol. It decreases TGF-β-induced Smad2 phosphorylation and TGF-β expression and prevents inhibition of DNA synthesis by TGF-β in Mv1Lu cells when used at a concentration of 50 μg/ml. Increased fecal excretion of cholestenone is correlated with an increased risk of colorectal cancer. Cholestenone reduces serum cholesterol levels in a variety of animal models but is toxic to rats when administered at doses of 700-1,000 mg/kg per day, inducing hypertrophy in and reducing the activity of the adrenal gland. It has been used as synthetic intermediate in the synthesis of steroids.
Chemical Properties
white to light yellow crystals or powder
Uses
4-Cholesten-3-one is used as a chiral building block for proteomics research. It is an intestinal metabolite of cholesterol and exhibits an anti-obesity effect on animals.
General Description
Cholestenone is a cholesterol metabolite and analog, which substitutes membrane cholesterol and elevates membrane fluidity.
4-Cholesten-3-one Preparation Products And Raw materials
4-Cholesten-3-one Suppliers
Global( 184)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Sri Neelima Laboratories | +91-7981733602 +91-9849736989 | Telangana, India | 205 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| Symax Fine Chemicals | 08068442240Ext 881 | Hyderabad, India | 51 | 58 | Inquiry |
| Sainor Laboratories Private Limited | 09666644167 | Hyderabad, India | 66 | 58 | Inquiry |
| Evans Fine Chem | 08048602255 | Hyderabad, India | 289 | 58 | Inquiry |
| Anji Biosciences | +91 40 40154989 | Hyderabad, India | 201 | 58 | Inquiry |
| Hritik Chemicals Pvt., Ltd. | 91-22-26313359 | Maharashtra, India | 88 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Sri Neelima Laboratories | 58 |
| CHEMSWORTH | 30 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Reax Chemicals | 58 |
| Symax Fine Chemicals | 58 |
| Sainor Laboratories Private Limited | 58 |
| Evans Fine Chem | 58 |
| Anji Biosciences | 58 |
| Hritik Chemicals Pvt., Ltd. | 58 |
| Clearsynth Labs | 58 |
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4-Cholestene-3-one
(+)-4-Cholesten-3-one >
(+)-4-Cholesten-3-one
(+)-3-Oxo-4-Cholestene
601-57-0
Complex Molecules
Chiral Building Blocks
Asymmetric Synthesis
Steroids
Steroids (Others)
Steroids
Steroids (Others)
Biochemistry