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Phosphodiesterase I

Phosphodiesterase I  Structure
CAS No.
9025-82-5
Chemical Name:
Phosphodiesterase I
Synonyms
EC 3.1.4.1;Power phos;IUB: 3.1.4.1;5'-EXONUCLEASE;PHOSPHODIESTERAS;EC 3.1.4.1 TYPE V;VENOM EXONUCLEASE;PHOSPHODIESTERASE;EC 3.1.4.1 TYPE VI;EC 3.1.4.1 TYPE IV
CBNumber:
CB4133193
Molecular Formula:
NULL
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2024/7/2 8:55:07

Phosphodiesterase I Properties

storage temp. -20°C
form crude dried venom
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H334
Precautionary statements  P261-P284-P304+P340-P342+P311a-P501a
Hazard Codes  T+
Risk Statements  26/27/28
Safety Statements  36/37/39-45
RIDADR  2811
WGK Germany  3
RTECS  SZ5999500
HazardClass  6.1(a)
PackingGroup  II

Phosphodiesterase I price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P4506 Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake) Type IV, crude dried venom 9025-82-5 100MG ₹8913.3 2022-06-14 Buy
Sigma-Aldrich(India) P4506 Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake) Type IV, crude dried venom 9025-82-5 500MG ₹28438.2 2022-06-14 Buy
Sigma-Aldrich(India) P3243 Phosphodiesterase I from Crotalus adamanteus venom vial of ≥100?units, Purified 9025-82-5 1VIAL ₹19691.4 2022-06-14 Buy
Sigma-Aldrich(India) P3134 Phosphodiesterase I from Crotalus adamanteus venom Type VI, crude dried venom 9025-82-5 100MG ₹23964.9 2022-06-14 Buy
Product number Packaging Price Buy
P4506 100MG ₹8913.3 Buy
P4506 500MG ₹28438.2 Buy
P3243 1VIAL ₹19691.4 Buy
P3134 100MG ₹23964.9 Buy

Phosphodiesterase I Chemical Properties,Uses,Production

Description

The food enzyme phosphodiesterase I (oligonucleotide 5′‐nucleotidohydrolase; EC 3.1.4.1) is produced with the non‐genetically modified Leptographium procerum strain FDA by DSM Food Specialties B.V. The food enzyme is free from viable cells of the production organism. It is intended to be used to process yeast and yeast products. Phosphodiesterase I exhibits phosphohydrolase activity against NAD, nucleoside diphosphate sugars, and nucleoside tniphosphates. The enzyme was first isolated from rattlesnake venom and has been the subject of several reviews. Razzell partially purified a mammalian PDE I from a porcine kidney, and subsequent cell fractionation studies by other workers demonstrated the enzyme in the plasma membrane of rat liver cells[1-2].

References

[1] D J Morley. “Distribution of phosphodiesterase I in normal human tissues.” Journal of Histochemistry & Cytochemistry 35 1 (1987): 75–82.
[2] on Food Contact Materials, EFSA Panel Enzymes and Processing Aids (CEP). “Safety evaluation of the food enzyme phosphodiesterase I from the non-genetically modified Leptographium procerum strain FDA.” EFSA Journal 22 4 (2024).

Biochem/physiol Actions

Phosphodiesterase I breaks phosphodiester bonds and catalyzes the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase I is released from eucaryotic plasma membranes by phosphatidylinositol-specific phospholipase C.

Phosphodiesterase I Preparation Products And Raw materials

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EC 3.1.4.1 TYPE IV EC 3.1.4.1 TYPE V EC 3.1.4.1 TYPE VI EC 3.1.4.1 IUB: 3.1.4.1 5'-EXONUCLEASE 5'-EXONUCLEASE TYPE IV 5'-EXONUCLEASE TYPE V 5'-EXONUCLEASE TYPE VI PHOSPHODIESTERASE I TYPE IV PHOSPHODIESTERASE I TYPE V PHOSPHODIESTERASE I TYPE VI OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE IV OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE V OLIGONUCLEATE 5'-NUCLEOTIDOHYDROLASE TYPE VI VENOM EXONUCLEASE 5'-phosphodiesterases phosphodiesterase I from bovine*intestinal mucosa phosphodiesterase I type vii*from crotalus atrox PUTRESCINE DIHYDROCHLORIDE PLANT CELL*CU LTURE TESTE PHOSPHODIESTERASE I TYPE V FROM*BOTHROPS ATROX Phosphodiesteraseifromcrotalusadamanteus phosphodiesterase i from crotalus adamanteus venom PHOSPHODIESTERASE (FROM CROTALUS DURISSUS) 5μ-Exonuclease, Oligonucleate 5μ-nucleotidohydrolase Phosphodiesterase I from Bothrops atrox Phosphodiesterase I from Crotalus atrox (Western Diamondback Rattlesnake) Phosphodiesterase I from Crotalus adamanteus venom,5′-Exonuclease, Oligonucleate 5′-nucleotidohydrolase Power phos PHOSPHODIESTERASE I Native Crotalus adamanteus venom Phosphodiesterase I Native Crotalus atrox (Western Diamondback Rattlesnake) Phosphodiesterase I Native Bothrops atrox Phosphodiesterase I phosphodiesterases PHOSPHODIESTERASE I USP/EP/BP Phosphodiesterase I From Crotalus Adamanteus Venom BR,20U/mg PHOSPHODIESTERAS Phosphodiesterase Ⅰ PHOSPHODIESTERASE 9025-82-5 Cyclic Nucleotide Metabolism Metabolomics Nucleotide Metabolism Biochemicals and Reagents BioChemical Cell Biology Cell Signaling and Neuroscience Enzymes General Metabolic Enzymes G Proteins and Cyclic Nucleotides General Metabolic Enzymes I-Z Enzymes, Inhibitors, and Substrates Enzyme Class Index 3.1.x.x Acting on esters 3.x.x.x Hydrolases