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PHOSPHODIESTERASE II

PHOSPHODIESTERASE II Structure
CAS No.
9068-54-6
Chemical Name:
PHOSPHODIESTERASE II
Synonyms
PDEII;EC 3.1.16.1;IUB: 3.1.16.1;3'-exonuclease;SPLEEN EXONUCLEASE;PhosphodiesteraseⅡ;PHOSPHODIESTERASE II;EXONUCLEASE I, E COLI;EC 3.1.16.1 TYPE I-SA;3'-EXONUCLEASE TYPE I-SA
CBNumber:
CB9131891
Molecular Formula:
Molecular Weight:
0
MOL File:
Mol file
Modify Date:
2024/7/2 8:55:40

PHOSPHODIESTERASE II Properties

storage temp. -20°C
form lyophilized powder
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P285-P304+P341-P342+P311-P501
WGK Germany  3

PHOSPHODIESTERASE II price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P9041 Phosphodiesterase II from bovine spleen lyophilized powder, ≥5.0?units/mg protein 9068-54-6 10UNITS ₹20379.6 2022-06-14 Buy
Sigma-Aldrich(India) P9041 Phosphodiesterase II from bovine spleen lyophilized powder, ≥5.0?units/mg protein 9068-54-6 25UNITS ₹34887.3 2022-06-14 Buy
Product number Packaging Price Buy
P9041 10UNITS ₹20379.6 Buy
P9041 25UNITS ₹34887.3 Buy

PHOSPHODIESTERASE II Chemical Properties,Uses,Production

Uses

The product has been used in the characterization of polynucleotide chain length, base composition, and identity of terminal nucleotide. The enzyme has also been used in excision of pyridyloxobutyl (POB) base adducts from DNA. Furthermore, it has been used along with micrococcal endonuclease to hydrolyze purified DNA to 3 -nucleoside monophosphates.

General Description

Phosphodiesterase (PDE) II belong to the PDE superfamily and includes subtypes from one to 11. They exists as a dimer and comprise a N-terminal regulatory domain, C-terminal prenylated domain and a Zn2+ containing catalytic domain. The bovine spleen PDE2 corresponds to a molecular weight of 65 kDa. It requires divalent cations for its enzymatic activity and has an optimum pH of 7.5.

Biochem/physiol Actions

Phosphodiesterase (PDE) breaks phosphodiester bonds. 3-Isobutyl-methylxanthine (IBMX) is a potential PDE2 inhibitor.

PHOSPHODIESTERASE II Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-EXONUCLEASE TYPE I-SA SPLEEN EXONUCLEASE SPLEEN PHOSPHODIESTERASE TYPE I-SA PDEII PHOSPHODIESTERASE, TYPE II, CALF SPLEEN PHOSPHODIESTERASE, TYPE II PHOSPHODIESTERASE II TYPE I-SA IUB: 3.1.16.1 EC 3.1.16.1 EC 3.1.16.1 TYPE I-SA EXONUCLEASE I, E COLI phosphodiesterase ii from calf spleen phosphodiesterase ii type I-sa from*bovine spleen POLYOXYETHYLENE (20) SORBITAN MONOLAURATE SOLUTION, 10% WATER PhosphodiesteraseIiExBovineSpleen PhosphodiesteraseIIfrombovinespleen 3'-exonuclease PHOSPHODIESTERASE II FROM BOVINE SPLEEN(10 - 15UNITS/VIAL) 3μ-Exonuclease, Spleen exonuclease, Spleen phosphodiesterase Spleen phosphodiesterase PHOSPHODIESTERASE II PhosphodiesteraseⅡ Native Bovine Phosphodiesterase II Phosphodiesterase II from bovine spleen lyophilized powder, >=5.0 units/mg protein 9068-54-6 BioChemical Nucleotide Metabolism General Metabolic Enzymes Metabolomics