Ribonuclease A
Melting point | 243 °C (dec.) |
---|---|
alpha | D25 (per mg N) -0.47° (c = 5) |
storage temp. | -20°C |
solubility | Reconstitute in 10mM acetate, pH 5.0 with or without 15mM calcium chloride |
form | solid |
color | white |
PH | pH : 8.0 |
biological source | protein from bovine pancreas |
Water Solubility | Soluble in water. |
Sensitive | Moisture Sensitive |
Specific Activity | 85-140Kunitz units/mg protein |
EPA Substance Registry System | Nuclease, ribo- (9001-99-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
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Signal word | Danger |
Hazard statements | H334 |
Precautionary statements | P261-P284-P501 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
RTECS | RF0760000 |
F | 10-21 |
TSCA | Yes |
HS Code | 35079090 |
Ribonuclease A price More Price(50)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | R6513 | Ribonuclease A from bovine pancreas for molecular biology, ≥70?Kunitz units/mg protein, lyophilized | 9001-99-4 | 10MG | ₹5117.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R7884 | Ribonuclease B from bovine pancreas BioReagent, ≥50?Kunitz units/mg protein, ≥80% (SDS-PAGE) | 9001-99-4 | 500μG | ₹4340.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R6513 | Ribonuclease A from bovine pancreas for molecular biology, ≥70?Kunitz units/mg protein, lyophilized | 9001-99-4 | 50MG | ₹13997.1 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R6513 | Ribonuclease A from bovine pancreas for molecular biology, ≥70?Kunitz units/mg protein, lyophilized | 9001-99-4 | 250MG | ₹52769.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | R7884 | Ribonuclease B from bovine pancreas BioReagent, ≥50?Kunitz units/mg protein, ≥80% (SDS-PAGE) | 9001-99-4 | 100MG | ₹66688.8 | 2022-06-14 | Buy |
Ribonuclease A Chemical Properties,Uses,Production
Chemical Properties
Lyophilized
General Description
Human chromosome 14q11.2 shows the presence of all human RNases. Only eight (RNase 1-8) of them were true called as canonical RNases. And the rest nine to thirteen are called as noncanonical RNases. Human RNase 1 is called as HP-RNase or human pancreatic RNase. Human RNase 2 is also called as EDN (eosinophils derived neurotoxin) that is isolated from eosinophils.
Purification Methods
Purify it by (NH4)2SO4 fractionation, followed by PC cellulose chromatography and affinity chromatography (using Sepharose 4B to which (G)n is covalently bonded). [Schmukler et al. J Biol Chem 250 2206 1975.] Ribozymes. These are ribonucleic acids which act like protein enzyme in catalyzing the making and breaking of peptide bonds as well as catalyzing reactions and cleavage of DNA and RNA molecules. The short RNAs are being intensively studied (see RNAi below). MicroRNAs (miRNA, see also below) are ubiquitous and are also genetically produced. They are involved in numerous reactions from splicing RNA, e.g. mRNA (messenger RNA) to controlling transcription of DNA to RNA, and translation of RNA to protein. Each miRNA is capable of being involved in a small number to hundreds of interactions with nucleic acids and with proteins.
Ribonuclease A Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4315 | 58 | Inquiry |
Transiom Genomics | 08068441066Ext 367 | Gujarat, India | 10 | 58 | Inquiry |
Select Sabkuch Online Traders Private Limited | 08048361370Ext 158 | Delhi, India | 2 | 58 | Inquiry |
Aarti Dye Chem | 08069023939Ext 853 | Gujarat, India | 12 | 58 | Inquiry |
Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6088 | 58 | Inquiry |
Jiangsu Boquan Biotechnology Co., Ltd. | +86-18168774353 | China | 248 | 58 | Inquiry |
Wuhan Fortuna Chemical Co., Ltd | +86-027-59207850 | China | 5971 | 58 | Inquiry |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | China | 19809 | 58 | Inquiry |
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