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Isocorynoxeine

Isocorynoxeine Structure
CAS No.
51014-29-0
Chemical Name:
Isocorynoxeine
Synonyms
Isocorynoxeine;Isocorynoxeine, BR;Isocorynoxeine USP/EP/BP;Isocorynoxeine (7-Isocorynoxeine);(16E,20α)-16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester;Methyl (E)-3-methoxy-2-((3S,6'R,7'S,8a'S)-2-oxo-6'-vinyl-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)acrylate;Methyl (E)-3-methoxy-2-((3S,6'R,7'S,8a'S)-2-oxo-6'-vinyl-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)acrylate;methyl (E)-2-[(3S,6'R,7'S,8'aS)-6'-ethenyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate;Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'S,6'R,7'S,8'aS)-;(alphaE,1'S,6'R,7'S,8'aS)-6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-alpha-(methoxymethylene)-2-oxospiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid methyl ester
CBNumber:
CB41483206
Molecular Formula:
C22H26N2O4
Molecular Weight:
382.46
MOL File:
51014-29-0.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:08

Isocorynoxeine Properties

Boiling point 562.7±50.0 °C(Predicted)
Density 1.25
solubility DMSO : 50 mg/mL (130.74 mM; Need ultrasonic)
form Powder
pka 13.54±0.60(Predicted)
color White to off-white

Isocorynoxeine Chemical Properties,Uses,Production

Description

The leaves of Mitragyna rotundlfolia grown in Burma have recently been found to contain this alkaloid. This is the first reported occurrence of the base in nature. The structure has been established from spectroscopic investigations.

Uses

7-Isocorynoxeine is a bioactive oxindole alkaloid in the Uncaria species. Displays wide array of beneficial cardiovascular and cardiocerebral vascular system effects.

References

Houghton, Shellard, Planta Med., 26, 104 (1974)

Isocorynoxeine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 145)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Chengdu Greenpure Biopharma CO.,Ltd 18283602253; +8618283602253 China 953 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29888 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3772 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
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ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23555 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 24099 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Henan Alfa Chemical Co., Ltd +8618339805032 China 13183 58 Inquiry
Isocorynoxeine (16E,20α)-16,17,18,19-Tetradehydro-17-methoxy-2-oxocorynoxan-16-carboxylic acid methyl ester (alphaE,1'S,6'R,7'S,8'aS)-6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-alpha-(methoxymethylene)-2-oxospiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid methyl ester Isocorynoxeine, BR Isocorynoxeine (7-Isocorynoxeine) Spiro[3H-indole-3,1'(5'H)-indolizine]-7'-acetic acid, 6'-ethenyl-1,2,2',3',6',7',8',8'a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1'S,6'R,7'S,8'aS)- Isocorynoxeine USP/EP/BP methyl (E)-2-[(3S,6'R,7'S,8'aS)-6'-ethenyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate Methyl (E)-3-methoxy-2-((3S,6'R,7'S,8a'S)-2-oxo-6'-vinyl-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)acrylate Methyl (E)-3-methoxy-2-((3S,6'R,7'S,8a'S)-2-oxo-6'-vinyl-2',3',6',7',8',8a'-hexahydro-5'H-spiro[indoline-3,1'-indolizin]-7'-yl)acrylate 51014-29-0 chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract