Isochlorogenic acid A
![Isochlorogenic acid A Structure](CAS/GIF/2450-53-5.gif)
- CAS No.
- 2450-53-5
- Chemical Name:
- Isochlorogenic acid A
- Synonyms
- 3,5-Dicaffeoylquinic acid;3,5-CQA;CJ 4-16-4;Isochloric acid A;Isochlorogenic acid A;3,5-Dicaffeylquinic acid;ISOCHLOROGENIC ACID A(SH);3',5'-Isochlorogenic acid A;Quinic acid 3,5-di-O-caffeate;Isochlorogenic acid A, froM Lonicera japonica
- CBNumber:
- CB81040694
- Molecular Formula:
- C25H24O12
- Molecular Weight:
- 516.46
- MOL File:
- 2450-53-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/9 9:30:51
Melting point | >175°C (dec.) |
---|---|
Boiling point | 826.2±65.0 °C(Predicted) |
Density | 1?+-.0.1 g/cm3(Predicted) |
storage temp. | -20°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
pka | 3.54±0.50(Predicted) |
form | Off-white to yellow/brown crystalline solid. |
color | Off-White to Pale Yellow |
Stability | Hygroscopic |
InChIKey | KRZBCHWVBQOTNZ-PSEXTPKNSA-N |
SAFETY
Risk and Safety Statements
Safety Statements | 24/25 |
---|---|
WGK Germany | 3 |
RTECS | GU8403966 |
HS Code | 29189900 |
Isochlorogenic acid A Chemical Properties,Uses,Production
Description
3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC50 = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC50 = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF).
Uses
Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent.
Isochlorogenic acid A Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | CHINA | 1824 | 58 | Inquiry |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | China | 9338 | 55 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29901 | 58 | Inquiry |
Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | China | 3424 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | China | 12261 | 58 | Inquiry |
Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
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