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Isochlorogenic acid A

Isochlorogenic acid A Structure
CAS No.
2450-53-5
Chemical Name:
Isochlorogenic acid A
Synonyms
3,5-Dicaffeoylquinic acid;3,5-CQA;CJ 4-16-4;Isochloric acid A;Isochlorogenic acid A;3,5-Dicaffeylquinic acid;ISOCHLOROGENIC ACID A(SH);3',5'-Isochlorogenic acid A;Quinic acid 3,5-di-O-caffeate;Isochlorogenic acid A, froM Lonicera japonica
CBNumber:
CB81040694
Molecular Formula:
C25H24O12
Molecular Weight:
516.46
MOL File:
2450-53-5.mol
MSDS File:
SDS
Modify Date:
2023/5/9 9:30:51

Isochlorogenic acid A Properties

Melting point >175°C (dec.)
Boiling point 826.2±65.0 °C(Predicted)
Density 1?+-.0.1 g/cm3(Predicted)
storage temp. -20°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 3.54±0.50(Predicted)
form Off-white to yellow/brown crystalline solid.
color Off-White to Pale Yellow
Stability Hygroscopic
InChIKey KRZBCHWVBQOTNZ-PSEXTPKNSA-N

SAFETY

Risk and Safety Statements

Safety Statements  24/25
WGK Germany  3
RTECS  GU8403966
HS Code  29189900

Isochlorogenic acid A price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SMB00131 3,5-Di-caffeoylquinic acid ≥95% (LC/MS-ELSD) 2450-53-5 1MG ₹27582.1 2022-06-14 Buy
Product number Packaging Price Buy
SMB00131 1MG ₹27582.1 Buy

Isochlorogenic acid A Chemical Properties,Uses,Production

Description

3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants. It has antioxidant, anti-inflammatory, and antiviral biological activities. 3,5-DCQA scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay (IC50 = 71.8 μM) and inhibits superoxide production in human neutrophils activated by N-formyl-Met-Leu-Phe (fMLF) and cytochalasin B (IC50 = 1.92 μM). It inhibits HIV-1 integrase 3''-end processing, strand transfer, and disintegration in a cell-free assay (IC50s = 0.33, 0.34, and 0.66 μg/ml, respectively) and inhibits HIV-1-induced cytotoxicity in MT-2 cells (ED50 = 1 μg/ml). In vivo, 3,5-DCQA (25 mg/kg) protects mice from acute lung injury induced by LPS and decreases neutrophil count in bronchoalveolar lavage fluid (BALF).

Uses

Isochlorogenic Acid A is a phenolic compound shown to provide protection against oxidative stress cells. DNA protective agent.

Isochlorogenic acid A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 219)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3424 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 12261 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry

Isochlorogenic acid A Spectrum

Isochlorogenic acid A Isochlorogenic acid A,3,5-Dicaffeoylquinic acid 3α,5β-Bis[[1-oxo-3-(3,4-dihydroxyphenyl)-2-propenyl]oxy]-1α,4α-dihydroxycyclohexane-1-carboxylic acid 1α,4α-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid 1β,4β-Dihydroxy-3β,5α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1α-cyclohexanecarboxylic acid 1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)acryloyloxy]cyclohexane-1-carboxylic acid 1β,4β-Dihydroxy-3β,5α-bis[3-(3,4-dihydroxyphenyl)propenoyloxy]cyclohexanecarboxylic acid 3β,5α-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β,4β-dihydroxycyclohexanecarboxylic acid 3,5-Dicaffeylquinic acid CJ 4-16-4 Quinic acid 3,5-di-O-caffeate ISOCHLOROGENIC ACID A(SH) Isochlorogenic acid A, froM Lonicera japonica Isochlorogenic acid A, 98%, from Lonicera japonica Thunb. 3,5-Di-O-caffeoylquinic acid,Isochlorogenic acid A Isochlorogenic acid A, 98%, from Lonicera japonica 3,5-CQA Cyclohexanecarboxylic acid, 3,5-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4-dihydroxy-, (1α,3R,4α,5R)- 3',5'-Isochlorogenic acid A 3,5-Dicaffeoylquinic acid (3R,5R)-3,5-Bis{[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoyl]oxy}-1,4-dihydroxycyclohexanecarboxylic acid Isochloric acid A (1R,3R,4S,5R)-3,5-Bis((3-(3,4-dihydroxyphenyl)acryloyl)oxy)-1,4-dihydroxy-3-methylcyclohexane-1-carboxylic acid 2450-53-5 The group of Chlorogenic acid chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Aromatic Phenols