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Isoalantolactone

Isoalantolactone Structure
CAS No.
470-17-7
Chemical Name:
Isoalantolactone
Synonyms
ISOHELENIN;ISOALANTOACTONE;isocoxiolactone;ISOALANTOLACTONE;(+)-Isoalantolactone;ISOALANTOLACTONE (RG);Isoalantolactone USP/EP/BP;(+)-Isoalantolactone|||Isohelenin;Naphtho[2,3-b]furan-2(3H)-one,decahydro-8a-;methyl-3,5-bis(methylene)-,(3aR,4aS,8aR,9aR)-
CBNumber:
CB9234785
Molecular Formula:
C15H20O2
Molecular Weight:
232.32
MOL File:
470-17-7.mol
MSDS File:
SDS
Modify Date:
2023/8/25 11:46:16

Isoalantolactone Properties

Melting point 115℃
Boiling point 364.9±42.0 °C(Predicted)
Density 1.07±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Soluble in DMSO (up to 50 mg/ml) or ethanol (30 mg/ml)
form solid
color White
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
LogP 3.420
CAS DataBase Reference 470-17-7(CAS DataBase Reference)
NIST Chemistry Reference Naphtho(2,3-b)furan-2(3h)-one, decahydro-8a-methyl-3,5-bis(methylene)-, (3ar-(3a«alpha»,4a«alpha»,8a«beta»,9a«alpha»))-(470-17-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P261-P272-P280-P302+P352-P333+P313-P321-P363-P501
Hazard Codes  Xn
Risk Statements  40
Safety Statements  22-36
HS Code  29322090

Isoalantolactone Chemical Properties,Uses,Production

Uses

Isoalantolactone is a sesquiterpene lactone used in the treatment of cancer. It can inhibit tumor cell growth and induce apoptosis.

Definition

ChEBI: A sesquiterpene lactone of the eudesmanolide group. It has been isolated from Inula helenium.

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11(13)-dien-12-oicacid,8-beta-hydroxy-eudesma-4(14gamma-lactone ISOALANTOACTONE ISOALANTOLACTONE ISOHELENIN (3ar,4as,8ar,9ar)-8a-methyl-3,5-dimethylene-decahydro-naphtho[2,3-b]furan-2-one methyl-3,5-bis(methylene)-,(3aR,4aS,8aR,9aR)- Naphtho[2,3-b]furan-2(3H)-one,decahydro-8a- (3aR)-3aα,4,4aα,5,6,7,8,8a,9,9aα-Decahydro-3,5-bismethylene-8aβ-methylnaphtho[2,3-b]furan-2(3H)-one (3aR,4aα,9aα)-3a,4,4a,5,6,7,8,8a,9,9a-Decahydro-8aβ-methyl-3,5-bis(methylene)naphtho[2,3-b]furan-2(3H)-one ISOALANTOLACTONE (RG) Isoalantolactone (3aR,4aS,8aR,9aR)-8a-Methyl-3,5-dimethylene-decahydro-naphtho[2,3-b]furan-2-one (3AR,4aS,8aR,9aR)-8a-methyl-3,5-dimethylenedecahydronaphtho[2,3-b]furan-2(3H)-one Isoalantolactone, 98%, from Inula helenium L. Naphtho[2,3-b]furan-2(3H)-one, decahydro-8a-methyl-3,5-bis(methylene)-, (3aR,4aS,8aR,9aR)- Isoalantolactone USP/EP/BP (+)-Isoalantolactone isocoxiolactone (+)-Isoalantolactone|||Isohelenin 470-17-7 Inhibitors Miscellaneous Natural Products chiral chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract