ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >Quinoline compounds >2-CHLORO-4-PHENYLQUINAZOLINE

2-CHLORO-4-PHENYLQUINAZOLINE

2-CHLORO-4-PHENYLQUINAZOLINE Structure
CAS No.
29874-83-7
Chemical Name:
2-CHLORO-4-PHENYLQUINAZOLINE
Synonyms
quinazoL;oro-4-phenyL;2-CHLORO-4-PHENYLQUIZOLINE;2-CHLORO-4-PHENYLQUINAZOLIN;2-Chloro-4-phenylq inazollne;2-CHLORO-4-PHENYLQUINAZOLINE;Quinazoline,2-chloro-4-phenyl-;2-CHLORO-4-PHENYLQUINAZOLINE ISO 9001:2015 REACH
CBNumber:
CB41490329
Molecular Formula:
C14H9ClN2
Molecular Weight:
240.69
MOL File:
29874-83-7.mol
MSDS File:
SDS
Modify Date:
2024/7/8 20:25:11

2-CHLORO-4-PHENYLQUINAZOLINE Properties

Melting point 113.0 to 117.0 °C
Boiling point 347.4±30.0 °C(Predicted)
Density 1.285±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
form powder to crystal
pka 0.24±0.30(Predicted)
color White to Orange to Green

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2933998090

2-CHLORO-4-PHENYLQUINAZOLINE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) C3173 2-Chloro-4-phenylquinazoline min. 98.0 % 29874-83-7 1G ₹7300 2022-05-26 Buy
TCI Chemicals (India) C3173 2-Chloro-4-phenylquinazoline min. 98.0 % 29874-83-7 5G ₹19500 2022-05-26 Buy
Product number Packaging Price Buy
C3173 1G ₹7300 Buy
C3173 5G ₹19500 Buy

2-CHLORO-4-PHENYLQUINAZOLINE Chemical Properties,Uses,Production

Uses

2-Chloro-4-phenylquinazoline acts as a reagent in the synthesis of MTH1 inhibitors that are potential cancer eradicators.

Synthesis

Synthesis_29874-83-7
A 2 L flask was charged with 35.0 g (175.8 mmol) of 2,4-dichloroquinoline,22.5 g (184.6 mmol) of phenylboronic acid, 6.1 g (5.3 mmol) of tetrakis(triphenylphosphine)palladium(0) were added to 800 mL of tetrahydrofuran and 400 mL of water, and the mixture was heated to 60 ?? C for 12 hours under a nitrogen stream. . The resulting mixture was added to methanol (3000 mL), and the crystallized solid was filtered and dissolved in toluene, filtered through silica gel / celite, and the organic solvent was removed in an appropriate amount, and then recrystallization from methanol gave Intermediate I-A52-1 (36.8 g, 87% yield).

2-CHLORO-4-PHENYLQUINAZOLINE Preparation Products And Raw materials

Global( 183)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Springchem New Material Technology Co.,Limited +86-021-62885108 +8613917661608 China 2068 57 Inquiry
Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20361 58 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16220 58 Inquiry
Hangzhou FandaChem Co.,Ltd. 008657128800458; +8615858145714 China 9338 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Speranza Chemical Co., Ltd. +86-86-075521030354 +8618688942810 China 723 55 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
2-CHLORO-4-PHENYLQUIZOLINE Quinazoline,2-chloro-4-phenyl- 2-CHLORO-4-PHENYLQUINAZOLIN oro-4-phenyL quinazoL 2-CHLORO-4-PHENYLQUINAZOLINE ISO 9001:2015 REACH 2-CHLORO-4-PHENYLQUINAZOLINE 2-Chloro-4-phenylq inazollne 29874-83-7 quinazoline