PUROMYCIN DIHYDROCHLORIDE
- CAS No.
- 58-58-2
- Chemical Name:
- PUROMYCIN DIHYDROCHLORIDE
- Synonyms
- pdh;PUROMYCIN;PUROMYCIN 2HCL;l-2hc;abs9143;Purinomycin;-9H-purin-9-yl);Puromycin dihydrochL;P638 dihydrochloride;-5-(6-(dimethylamino)
- CBNumber:
- CB4152905
- Molecular Formula:
- C22H30ClN7O5
- Molecular Weight:
- 507.98
- MOL File:
- 58-58-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2025/3/4 21:26:23
| Melting point | 168-170℃ |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | H2O: soluble50mg/mL (Sterilize stock solution by filtration using 0.22 μm filter then store in aliquots at 20 °C.) |
| form | solution |
| color | yellow-white |
| Water Solubility | Soluble in water |
| Merck | 14,7943 |
| BRN | 3853613 |
| Stability | Stable. Heat sensitive. Incompatible with strong oxidizing agents. |
| InChIKey | MKSVFGKWZLUTTO-NGOAXYITSA-N |
| EPA Substance Registry System | Adenosine, 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, dihydrochloride (58-58-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-40 | |||||||||
| Safety Statements | 24/25 | |||||||||
| RIDADR | 3249 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AU7355000 | |||||||||
| F | 3-8-10 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29419090 | |||||||||
| Toxicity | LD50 oral in guinea pig: 600mg/kg | |||||||||
| NFPA 704 |
|
PUROMYCIN DIHYDROCHLORIDE price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | P8833 | Puromycin dihydrochloride from Streptomyces alboniger powder, BioReagent, suitable for cell culture | 58-58-2 | 10MG | ₹5239.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P7255 | Puromycin dihydrochloride from Streptomyces alboniger ≥98% (HPLC), powder | 58-58-2 | 25MG | ₹8963.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P8833 | Puromycin dihydrochloride from Streptomyces alboniger powder, BioReagent, suitable for cell culture | 58-58-2 | 25MG | ₹9774.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P9620 | Puromycin dihydrochloride Ready Made Solution, from Streptomyces alboniger, 10?mg/mL in H2O | 58-58-2 | 10ML | ₹32550.78 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | P8833 | Puromycin dihydrochloride from Streptomyces alboniger powder, BioReagent, suitable for cell culture | 58-58-2 | 100MG | ₹34326.08 | 2022-06-14 | Buy |
PUROMYCIN DIHYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
white powder
Uses
Puromycin dihydrochloride is the salt of puromycin, a nucleoside antibiotic isolated from Streptomyces alboniger in the 1950s as an anti-trypansomal agent with antibiotic activity. While the salt shares the same pharmacological properties as puromycin free base, its greater water solubility offers advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems, the free base and salt may behave differently.
General Description
White powder.
Air & Water Reactions
Water soluble.
Reactivity Profile
PUROMYCIN DIHYDROCHLORIDE is sensitive to prolonged exposure to heat. . Behaves as a very weak acid in solution.
Fire Hazard
Flash point data for PUROMYCIN DIHYDROCHLORIDE are not available, but PUROMYCIN DIHYDROCHLORIDE is probably combustible.
Purification Methods
Puromycin dihydrochloride is purified by recrystallisation from H2O. The free base, [58-60-6] M 294.3, has m 175.5-177o (172-173o) (from H2O). The sulfate has m 180-187o dec (from H2O), and the picrate monohydrate has m 146-149o (from H2O). [Baker et al. J Am Chem Soc 77 1 1955, Fryth et al. J Am Chem Soc 80 3736 1958.] It is an inhibitor of aminopeptidase and terminates protein synthesis [Reboud et al. Biochemistry 20 5281 1981]. [Beilstein 26 III/IV 3704.]
PUROMYCIN DIHYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 323)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4315 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6088 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1841 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
| Anand Agencies | 91-20-24454597 | Maharashtra, India | 2332 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29859 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| Otto Chemie Pvt. Ltd. | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Triveni chemicals | 58 |
| HiMedia Laboratories | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Anand Agencies | 58 |
| Maas Pharma Chemicals | 58 |
| career henan chemical co | 58 |
58-58-2(PUROMYCIN DIHYDROCHLORIDE)Related Search:
PUROMYCIN(RG),PUROMYCIN
(S)-TETRAHYDROFURAN-3-AMINE HYDROCHLORIDE
(S)-3-AMINOTETRAHYDROFURAN
TETRAHYDRO-FURAN-3-YLAMINE HCL
Adenine hydrochloride hemihydrate
Adenine hydrochloride
Adenine Sulfate
N-(3-Aminopropyl)-imidazole
6-Dimethylaminopurine
PUROMYCIN DIHYDROCHLORIDE,PUROMYCIN 2HCL,PUROMYCIN DIHYDROCHLORIDE,PUROMYCIN
chevron_left
1of4
chevron_right
Puromycin dihydrochloride hydrate,99%
3’-(alpha-amino-p-methoxyhydrocinnamamido)-3’-deoxy-n,n-dimethyl-adenosin
adenosine,3’-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3’-deoxy-n,n-dim
dihydrochloride,(s)-ethyl
PUROMYCIN Dihydrochloride Dihydrate 96%
3'-[[12-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYL-ADENOSINE 2HCL
3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYL-ADENOSINE 2HCL
3'-(A-AMINO-P-METHOXYHYDROCINNAMAMIDO)-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
3'-(A-AMINO-P-METHOXY-HYDOCINNAMAMIDO)-3'-DEXOY-N,N-DIMETHYLADENOSINE 2HCL
3'-(ALPHA-AMINO-P-METHOXY-HYDROCINNAMINO-3'-DEOXY-N,N-DIMETHY-ADENOSINE) 2HCL
3'-(ALPHA-AMINO-P-METHOXY-HYDROCINNAMIDO-3'-DEOXY-N,N-DIMETHYL-ADENOSINE) 2HCL
3'-[ALPHA-AMINO-P-METHOXYHYDROCINNAMAMIDO]-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
3'-(ALPHA-AMINO-P-METHOXYHYDROCINNAMAMIDO)-3'-DEOXY-N,N-DIMETHYLADENOSINE, 2HCL
3'-(ALPHA-AMINO-P-METHOXYHYDROCINNAMADIO)-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
PUROMYCIN, CELL CULTURE TESTED
Puromycin, 3-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3-deoxy-N,N-dimethyladenosine dihydrochloride
Puromycin hydrate dihydrochloride
PuroMycin dihydrochloride hydrate, 99% 10MG
PuroMycin dihydrochlorid
Puromycin dihydrochloride (animal free)
StyloMycin dihydrochloride, CL 13900 dihydrochloride, CL16536, NSC 3055, P638 dihydrochloride.
3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine,hydrochloride (1:2)
Puromycin 2HCl (S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
Puromycin dihydrochloride
(S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
Puromycin 2hydrochloride
-2-Amino-N-((2S,3S,4R,5R)
-4-hydroxy-2-(hydroxymethyl)
-5-(6-(dimethylamino)
-9H-purin-9-yl)
propanamide dihydrochloride
tetrahydrofuran-3-yl)
PUROMYCIN DIHYDROCHLORIDE
(S) 3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYLADENOSINE 2HCL
(S)-3'-[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYLADENOSINE
l-2hc
puromycinhydrochloride
stylomycinhydrochloride
PUROMYCIN DIHYDROCHLORIDE CELL*CULTURE T ESTED
PUROMYCIN READY MADE SOLUTION
PUROMYCIN DIHYDROCHLORIDE FROM STREPTO-M YCES ALBO-NIGER
(S)-3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
PUROMYCIN DIHYDROCHLORIDE CELL CULTURE REAGENT
PUROMYCIN DIHYDROCHLORIDE ULTRA PURE GRADE 98+%
Puromycin.Cellculturedtested
Puromycin,Solution,CellCultureTested
Adenosine, 3-(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropylamino-3-deoxy-N,N-dimethyl-, dihydrochloride
3'-[α-amino-p-methoxyhydrocinnamamido]-3'-deoxy-n,n-dimethyladenosine dihydrochloride
PUROMYCINDIHYROCHLORIDE
DIHYDROGEN PUROMYCIN DICHLORIDE
Puromycin dihydrochL
CL 13900 dihydrochloride
P638 dihydrochloride
STYLOMYCIN HYDROCHLORIDE; CL 13900 DIHYDROCHLORIDE; CL16536; NSC 3055; P638 DIHYDROCHLORIDE
PUROMYCIN DIHYDROCHLORIDE USP/EP/BP
abs9143
(S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamide dihydrochloride
Puromycin 2HCl (CL13900)