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PUROMYCIN

PUROMYCIN Structure
CAS No.
53-79-2
Chemical Name:
PUROMYCIN
Synonyms
achromycin;Stylomycin;1-mm;3123l;p-638;C01610;cl16536;cl13,900;nsc-3055;PUROMYCIN
CBNumber:
CB7152906
Molecular Formula:
C22H29N7O5
Molecular Weight:
471.51
MOL File:
53-79-2.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

PUROMYCIN Properties

Melting point 175.5-177°
alpha D25 -11° (ethanol)
Boiling point 572.65°C (rough estimate)
Density 1.3119 (rough estimate)
refractive index 1.7010 (estimate)
RTECS AU7350000
pka 6.8, 7.2(at 25℃)
form Liquid
Water Solubility Soluble in water (50 mg/ml at 20°C).
EPA Substance Registry System Adenosine, 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl- (53-79-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312a-P330-P501a
RIDADR  3249
HazardClass  6.1(b)
PackingGroup  III
Toxicity LD50 in mice (mg/kg): 350 i.v.; 525 i.p.; 675 orally (Porter, 1952)

PUROMYCIN Chemical Properties,Uses,Production

Chemical Properties

Crystals.

Uses

Puromycin is a nucleoside antibiotic isolated from Streptomyces alboniger in the 1950s as an anti-trypansomal agent with antibiotic activity. Puromycin is non-selective, inhibiting RNA by blocking ribosomal translation. Puromycin is used in cell biology to select mammalian cell lines that have been transformed by vectors that express puromycin-N-acetyl-transferase.

Definition

ChEBI: An aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that causes premature chain termination during translation taking place in the ribosome.

Hazard

Toxic to living cells of all kinds.

PUROMYCIN Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 87)Suppliers
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InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
PUROMYCIN(RG) C01610 PHENYLANTHROLINE Hydrate, 1,10-(RG) AchroMycin, StilloMycin, StyloMycin, CL 13900, 3123L, P638, BacterenoMycin (s)-3’-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3’-deoxy-n,n-dimethy 1-mm 3’-(alpha-amino-p-methoxyhydrocinnamamido)-3’-deoxy-n,n-dimethyl-adenosinl 3’-(l-alpha-amino-p-methoxyhydrocinnamamido)-3’-deoxy-n,n-dimethyladenosine 3123l 6-dimethylamino-9-(3’-(p-methoxy-l-phenylalanylamino)-beta-d-ribofuranosyl)- achromycin(purinederivative) cl13,900 cl16536 nsc-3055 p-638 stillomycin PUROMYCIN Adenosine, 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl- PUROMYCIN USP/EP/BP Puromycin (CL13900) achromycin Stylomycin 53-79-2 C22H29N7O5