2-Octyl-1-dodecanol
- CAS No.
- 5333-42-6
- Chemical Name:
- 2-Octyl-1-dodecanol
- Synonyms
- 1-Dodecanol, 2-octyl-;OCTYL DODECANOL;2-OctyL;exxal20;BASF OD;eutanolg;Guerbet20;rilanitg20;9-Icosanol;JARCOL 1-20
- CBNumber:
- CB4164735
- Molecular Formula:
- C20H42O
- Molecular Weight:
- 298.55
- MOL File:
- 5333-42-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/30 14:17:11
| Melting point | −1-1 °C(lit.) |
|---|---|
| Boiling point | 234-238 °C/33 mmHg(lit.) |
| Density | 0.838 g/mL at 25 °C(lit.) |
| vapor pressure | 0.1Pa at 148.85℃ |
| refractive index | n20/D 1.453(lit.) |
| Flash point | 113 °C |
| storage temp. | 2-8°C |
| solubility | Practically insoluble in water, miscible with ethanol (96 per cent). |
| pka | 15.03±0.10(Predicted) |
| color | Colourless |
| Water Solubility | 10μg/L at 23℃ |
| InChIKey | LEACJMVNYZDSKR-UHFFFAOYSA-N |
| LogP | 8.63 at 20℃ |
| EPA Substance Registry System | 2-Octyldodecanol (5333-42-6) |
2-Octyl-1-dodecanol price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 464481 | 2-Octyl-1-dodecanol 97% | 5333-42-6 | 25ML | ₹3009.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1155 | Octyldodecanol Pharmaceutical Secondary Standard; Certified Reference Material | 5333-42-6 | 1G | ₹8995.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 464481 | 2-Octyl-1-dodecanol 97% | 5333-42-6 | 100ML | ₹9212.08 | 2022-06-14 | Buy |
| TCI Chemicals (India) | O0429 | 2-n-Octyl-1-dodecanol min. 90.0 % | 5333-42-6 | 25ML | ₹2100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | O0429 | 2-n-Octyl-1-dodecanol min. 90.0 % | 5333-42-6 | 500ML | ₹18500 | 2022-05-26 | Buy |
2-Octyl-1-dodecanol Chemical Properties,Uses,Production
Chemical Properties
2-Octyl-1-dodecanol is clear, colourless or yellowish, oily liquid.
Uses
2-Octyl-1-dodecanol have been used as a emulsion stabilizer for polymer matrix patches.
Production Methods
2-Octyl-1-dodecanol is produced by the condensation of two molecules of decyl alcohol. It also occurs naturally in small quantities in plants.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Pharmaceutical Applications
Octyldodecanol is widely used in cosmetics and pharmaceutical
applications as an emulsifying and opacifying agent. It is primarily
used in topical applications because of its lubricating and emollient
properties.
Octyldodecanol has been used in the preparation of oil/water
microemulsions investigated as the vehicle for the dermal administration
of drugs having no or low skin penetration.Octyldodecanol
has also been evaluated as a solvent for naproxen when
applied topically.Studies of estimated permeability coefficient
suggest that octyldodecanol could be a potential dermal permeation
enhancer.
Safety Profile
An eye and severe skin irritant.When heated to decomposition it emits acrid smoke andirritating vapors.
Safety
Octyldodecanol is widely used in cosmetics and topical pharmaceutical
formulations, and is generally regarded as nontoxic and
nonirritant at the levels employed as an excipient.
In acute oral toxicity studies in rats fed 5 g/kg of undiluted
octyldodecanol, no deaths were observed.In an acute dermal
toxicity study, intact and abraded skin sites of guinea pigs were
treated with 3 g/kg of undiluted octyldodecanol under occlusive
patches; no deaths occurred and no gross skin lesions were
observed.Octyldodecanol caused either no ocular irritation or
minimal, transient irritation in the eyes of rabbits.However, some
sources describe undiluted octyldodecanol as an eye and severe skin
irritant.
storage
The bulk material should be stored in a well-closed container in a cool, dry place, protected from light. In the original unopened container, octyldodecanol can be stored for 2 years protected from moisture at below 30°C.
Incompatibilities
2-Octyl-1-dodecanol is generally compatible with most materials encountered in cosmetic and pharmaceutical formulations.
Regulatory Status
Included in the FDA Inactive Ingredients Database (topical, transdermal, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
2-Octyl-1-dodecanol Preparation Products And Raw materials
Raw materials
Preparation Products
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| Monachem Specialities LLP | +91-0265-2966227 +91-02652966227 | Gujarat, India | 35 | 58 | Inquiry |
| TRUUCHEM TECHNOLOGIES PRIVATE LIMITED | +91-8619349510 +91-8619349510 | Bangalore, India | 82 | 58 | Inquiry |
| Novosynth Healthcare Private Limited | 08048361219Ext 135 | Karnataka, India | 4 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
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| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Anmol Chemicals (Mubychem Group Company) | 91-22-23770100 | Maharashtra, India | 63 | 58 | Inquiry |
| Pharmaffiliates Analytics & Synthetics (P) Ltd. | 91-172-5066494 | Haryana, India | 631 | 58 | Inquiry |
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