CORTISOL-9,11,12,12-D4
- CAS No.
- 73565-87-4
- Chemical Name:
- CORTISOL-9,11,12,12-D4
- Synonyms
- Hycort-d4;Acticort-d4;Hycortol-d4;Texacort-d4;TiMocort-d4;Cortisol-d4;DerMacort-d4;Hydrocortal-d4;[2H4]-Cortisol;Deuterated cortisol
- CBNumber:
- CB4234270
- Molecular Formula:
- C21H26D4O5
- Molecular Weight:
- 366.49
- MOL File:
- 73565-87-4.mol
- Modify Date:
- 2023/5/18 11:31:18
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P280-P308+P313-P405-P501 |
| Hazard Codes | Xn,T,F |
| Risk Statements | 63-39/23/24/25-23/24/25-11 |
| Safety Statements | 36/37-45-16-7 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
CORTISOL-9,11,12,12-D4 price More Price(2)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C-113 | Cortisol-D4 (9,11,12, 12-D4) solution 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant? | 73565-87-4 | 1ML | ₹46233.58 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 705594 | Cortisol-9,11,12,12-d4 ≥98 atom % D, ≥98% (CP) | 73565-87-4 | 5MG | ₹85755.65 | 2022-06-14 | Buy |
CORTISOL-9,11,12,12-D4 Chemical Properties,Uses,Production
Description
Hydrocortisone-d4 is intended for use as an internal standard for the quantification of hydrocortisone/cortisol by GC- or LC-MS. Cortisol, known as hydrocortisone when used as a therapeutic, is a glucocorticoid produced by the adrenal cortex in response to adrenocorticotropic hormone (ACTH). It is an agonist at the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR), with an approximately 6- to 10-fold greater affinity for MR. Cortisol production is increased during periods of stress, and it is a major effector molecule in the hypothalamic-pituitary-adrenal axis (HPA) stress response. Cortisol levels increase with age and are often elevated in major depressive disorder, certain forms of hypertension, and Parkinson''s disease.
Chemical Properties
White Solid
Uses
Anti-inflammatory hormone
General Description
Cortisol, also known as hydrocortisone, is a glucocorticoid produced by the adrenal gland. This stable labeled internal standard is suitable for quantitation of cortisol levels in whole blood by LC-MS/MS for newborn screening of congenital adrenal hyperplasia (CAH) and in serum or plasma by LC-MS/MS for determination of several diseases including Cushing′s syndrome, Addison′s disease, and Sheehan′s syndrome.
CORTISOL-9,11,12,12-D4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SIMSON PHARMA LIMITED | +91-8291074273 | Shanghai, India | 228 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| ABCR GmbH & CO. KG | 49 721 95061 0 | Germany | 6846 | 75 | Inquiry |
| United States Biological | 800.520.3011 or 781.639.5092 | United States | 6256 | 80 | Inquiry |
| Nanjing Shizhou Biology Technology Co.,Ltd | 18351873721 | China | 8298 | 58 | Inquiry |
| Changzhou Bojia Biomedical Technology Co., Ltd. | 2122619822 | China | 18488 | 58 | Inquiry |
| Reer Technology (Shanghai) Co., LTD | 021-64400900 15800436310 | China | 4113 | 58 | Inquiry |
| Shanghai Aladdin Biochemical Technology Co.,Ltd. | +86-18521732826 | China | 48467 | 58 | Inquiry |
| Cato Research Chemicals Inc. | 020-81960175-877 18933936954 | China | 7738 | 58 | Inquiry |